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The map label for this gene is NikR [C]

Identifier: 20806771

GI number: 20806771

Start: 254251

End: 254715

Strand: Reverse

Name: NikR [C]

Synonym: TTE0250

Alternate gene names: 20806771

Gene position: 254715-254251 (Counterclockwise)

Preceding gene: 20806782

Following gene: 20806770

Centisome position: 9.47

GC content: 37.2

Gene sequence:

>465_bases
GTGCTATTATTTTCTAAGAAAATAGCACAGCATAAAGGAGGGATTTGTCTGGAAGGCATCGTGCGCTTTGGCGTTTCCAT
GGAGTCAAAGCTTTTAAAACAGTTTGACGAACTGATTAAAAAGAAAAATTATAATAACAGGTCCGAAGCCATAAGAGACC
TCATTAGAGATTTCATAGTAGAAAATCAGTGGGAAGCAGAGGATGTTGAGACAATAGGCACAATAACCTATGTGTTCAAC
CATGAGGTTAGAGAAATTAACGATAAACTCACAGATATGCAGCACAAACACTATAAAAACATCATATCCACTATGCATGT
ACATCTAGATGAGCACAACTGCATAGAAGTCATGATAGTAAGAGGCAAAGCAAAAGAAATTGTGAAGATCGCCGATGAAA
TAATAAGCACAAGGGGAGTAAAGCATGGAAAGCTTGTAATGACTACAACCGGTGAAAATTTATGA

Upstream 100 bases:

>100_bases
TGATGGCCTACCATCAACTTTCAATTTCATTTTATAACCCCAACATTAAAAGAACATTAATGAAAAATTAATTTTTTGAA
ATTGACTCCTCTAAAAAATA

Downstream 100 bases:

>100_bases
GAGGTGAGGATTTATGCATATACCTGACGGGTACTTGAGCCCTCAGACATGCGCTGTAATGGGGGCCGCCATGGTTCCTG
TTCTCTATAAATCCGTAAAA

Product: nickel responsive regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIVENQWEAEDVETIGTITYVFN
HEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIVRGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL

Sequences:

>Translated_154_residues
MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIVENQWEAEDVETIGTITYVFN
HEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIVRGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL
>Mature_154_residues
MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIVENQWEAEDVETIGTITYVFN
HEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIVRGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL

Specific function: Transcriptional regulator (Potential)

COG id: COG0864

COG function: function code K; Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory CopG/NikR family

Homologues:

Organism=Escherichia coli, GI1789892, Length=108, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NIKR_THETN (Q8R5U7)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_621942.1
- ProteinModelPortal:   Q8R5U7
- SMR:   Q8R5U7
- GeneID:   997598
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0250
- NMPDR:   fig|273068.3.peg.1043
- HOGENOM:   HBG646378
- OMA:   CLEVLVV
- ProtClustDB:   PRK04460
- BioCyc:   TTEN273068:TTE0250-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00476
- InterPro:   IPR013321
- InterPro:   IPR002145
- InterPro:   IPR022988
- InterPro:   IPR010985
- InterPro:   IPR014864
- Gene3D:   G3DSA:1.10.1220.10
- Gene3D:   G3DSA:3.30.70.1150

Pfam domain/function: PF08753 NikR_C; PF01402 RHH_1; SSF47598 Met_repress_like

EC number: NA

Molecular weight: Translated: 17834; Mature: 17834

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIV
CCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ENQWEAEDVETIGTITYVFNHEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
RGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIV
CCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ENQWEAEDVETIGTITYVFNHEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
RGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336