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The map label for this gene is NagA [H]

Identifier: 20806755

GI number: 20806755

Start: 237887

End: 239059

Strand: Direct

Name: NagA [H]

Synonym: TTE0232

Alternate gene names: 20806755

Gene position: 237887-239059 (Clockwise)

Preceding gene: 20806754

Following gene: 20806756

Centisome position: 8.85

GC content: 35.72

Gene sequence:

>1173_bases
ATGGGGAGGATATTAAAAGTGAAAAAGCTTATTTTAAAGAATGCAGAGATATATAAAGAAGAGGAGATACTCTATAATGG
TGATTTGTTAATTGAAGAGGGCAAAATTTCTAAATTAGGCAGAAACATTTCGGAAATAAATGCAGAAGTGATTGATTTAA
AAGGTAAAAAAATAGTACCGGGATTCATTGATATACATATACATGGCGGTGTAGGTTATGATACCATGGATGCAACTTAT
GAAGCGTTAAACAATATTTCTGTGCATTTAGCTAAACATGGAGTTACAAGTTTTTGCCCAACTACTATGACAATGGATAT
TCCTGATATTTTAAGGGCTTTAGAGAATGTAAAAGAAACAATGAAAAAAGGGGTAGAAGGTGCAGAGGTCCTAGGAGCGT
ATGTAGAAGGTCCTTTCATAAGTAAAGAGCATAAAGGAGCTCAAGATGAAAAATACGTTTTAGATCCGGATAAGGAATTG
TTTGATCAATTTTATGAAGTAGCAGGAGGTAATATAAAAGTTATTATTTTGGCTCCGGAAAAAGATCCATCAGGGGACTT
TATAAAACATGTGATAAAAAAAGGAGTTAAAGTCTCTTTAGGGCATACCAGTGCTTCTTATGAAGAGATGAAAAGAGGAG
TAGATTATGGAGCAACAATTGCTGTACACACGTATAATGGCATGAAGGGTTTCCACCACAGAGAGCCAGGAGCGTTGGGA
GAAGTATTTTTAGATGACAGAATATATGGAGAGCTTATATGTGATTTCATACACTCTCACCCTGCAGCAGTTAAATTGCT
TGTGAAAATAAAGGGTGTGGATAAAATTATTTTAATTTCCGATGCTATGGCTGCTTGTGGGCTAGGGGATGGAGAGTATA
GCCTTGGGGGACAAAAAGTGTACGTAAAAAATGGAGAAGCGAGACTTAAAAATGGGACTTTGGCGGGAAGTACCCTGACA
TTAGATAAGGCTTTGCAAAATATGACAAATTTAGGTATTTCCCTTTTTGATGCTGTTAAAATGGTGTCTACTAATGCTTC
CAAAGCGATAGGGATTTATGACAAAAAAGGGAGTATTGCAGTTGGAAAAGATGCGGATATAGTAGTATTAGATAGCGATC
TTAGTGTATATATGACAATTGTAGGTGGGAAAATTGTATATTCAAAAGAATGA

Upstream 100 bases:

>100_bases
AAATTTAAAAAGTTAAAGGTAGGCAAGTTTAAATTGTCTACCTTTAACTTTCTCTTTTTCTTTTTCGTGATATAATTTTT
GTAAGAAATTTAAAATTTAT

Downstream 100 bases:

>100_bases
AGGAGAGAACTACTATCTTAAAAAAGGAACTCCCTATGAAGTAGAAATGTCAAAGGAGATATTAGGCAAGATAGATAAAA
TTGTTCTTAAAGCTATTGAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MGRILKVKKLILKNAEIYKEEEILYNGDLLIEEGKISKLGRNISEINAEVIDLKGKKIVPGFIDIHIHGGVGYDTMDATY
EALNNISVHLAKHGVTSFCPTTMTMDIPDILRALENVKETMKKGVEGAEVLGAYVEGPFISKEHKGAQDEKYVLDPDKEL
FDQFYEVAGGNIKVIILAPEKDPSGDFIKHVIKKGVKVSLGHTSASYEEMKRGVDYGATIAVHTYNGMKGFHHREPGALG
EVFLDDRIYGELICDFIHSHPAAVKLLVKIKGVDKIILISDAMAACGLGDGEYSLGGQKVYVKNGEARLKNGTLAGSTLT
LDKALQNMTNLGISLFDAVKMVSTNASKAIGIYDKKGSIAVGKDADIVVLDSDLSVYMTIVGGKIVYSKE

Sequences:

>Translated_390_residues
MGRILKVKKLILKNAEIYKEEEILYNGDLLIEEGKISKLGRNISEINAEVIDLKGKKIVPGFIDIHIHGGVGYDTMDATY
EALNNISVHLAKHGVTSFCPTTMTMDIPDILRALENVKETMKKGVEGAEVLGAYVEGPFISKEHKGAQDEKYVLDPDKEL
FDQFYEVAGGNIKVIILAPEKDPSGDFIKHVIKKGVKVSLGHTSASYEEMKRGVDYGATIAVHTYNGMKGFHHREPGALG
EVFLDDRIYGELICDFIHSHPAAVKLLVKIKGVDKIILISDAMAACGLGDGEYSLGGQKVYVKNGEARLKNGTLAGSTLT
LDKALQNMTNLGISLFDAVKMVSTNASKAIGIYDKKGSIAVGKDADIVVLDSDLSVYMTIVGGKIVYSKE
>Mature_389_residues
GRILKVKKLILKNAEIYKEEEILYNGDLLIEEGKISKLGRNISEINAEVIDLKGKKIVPGFIDIHIHGGVGYDTMDATYE
ALNNISVHLAKHGVTSFCPTTMTMDIPDILRALENVKETMKKGVEGAEVLGAYVEGPFISKEHKGAQDEKYVLDPDKELF
DQFYEVAGGNIKVIILAPEKDPSGDFIKHVIKKGVKVSLGHTSASYEEMKRGVDYGATIAVHTYNGMKGFHHREPGALGE
VFLDDRIYGELICDFIHSHPAAVKLLVKIKGVDKIILISDAMAACGLGDGEYSLGGQKVYVKNGEARLKNGTLAGSTLTL
DKALQNMTNLGISLFDAVKMVSTNASKAIGIYDKKGSIAVGKDADIVVLDSDLSVYMTIVGGKIVYSKE

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=433, Percent_Identity=30.715935334873, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI224922791, Length=429, Percent_Identity=30.7692307692308, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1786892, Length=385, Percent_Identity=31.4285714285714, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553768, Length=395, Percent_Identity=31.6455696202532, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19920392, Length=405, Percent_Identity=32.8395061728395, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI281361140, Length=411, Percent_Identity=31.6301703163017, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42378; Mature: 42246

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRILKVKKLILKNAEIYKEEEILYNGDLLIEEGKISKLGRNISEINAEVIDLKGKKIVP
CCCHHHHHHHHHHCHHHHCCCEEEECCCEEEECCCHHHHCCCHHHCCCEEEEECCCEECC
GFIDIHIHGGVGYDTMDATYEALNNISVHLAKHGVTSFCPTTMTMDIPDILRALENVKET
CEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHH
MKKGVEGAEVLGAYVEGPFISKEHKGAQDEKYVLDPDKELFDQFYEVAGGNIKVIILAPE
HHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEECC
KDPSGDFIKHVIKKGVKVSLGHTSASYEEMKRGVDYGATIAVHTYNGMKGFHHREPGALG
CCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
EVFLDDRIYGELICDFIHSHPAAVKLLVKIKGVDKIILISDAMAACGLGDGEYSLGGQKV
CEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECHHHHCCCCCCCCCCCCEEE
YVKNGEARLKNGTLAGSTLTLDKALQNMTNLGISLFDAVKMVSTNASKAIGIYDKKGSIA
EEECCCEEECCCEECCCEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCEE
VGKDADIVVLDSDLSVYMTIVGGKIVYSKE
ECCCCCEEEECCCCEEEEEEECCEEEEECC
>Mature Secondary Structure 
GRILKVKKLILKNAEIYKEEEILYNGDLLIEEGKISKLGRNISEINAEVIDLKGKKIVP
CCHHHHHHHHHHCHHHHCCCEEEECCCEEEECCCHHHHCCCHHHCCCEEEEECCCEECC
GFIDIHIHGGVGYDTMDATYEALNNISVHLAKHGVTSFCPTTMTMDIPDILRALENVKET
CEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHH
MKKGVEGAEVLGAYVEGPFISKEHKGAQDEKYVLDPDKELFDQFYEVAGGNIKVIILAPE
HHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEECC
KDPSGDFIKHVIKKGVKVSLGHTSASYEEMKRGVDYGATIAVHTYNGMKGFHHREPGALG
CCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
EVFLDDRIYGELICDFIHSHPAAVKLLVKIKGVDKIILISDAMAACGLGDGEYSLGGQKV
CEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECHHHHCCCCCCCCCCCCEEE
YVKNGEARLKNGTLAGSTLTLDKALQNMTNLGISLFDAVKMVSTNASKAIGIYDKKGSIA
EEECCCEEECCCEECCCEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCEE
VGKDADIVVLDSDLSVYMTIVGGKIVYSKE
ECCCCCEEEECCCCEEEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]