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The map label for this gene is anmK

Identifier: 20806743

GI number: 20806743

Start: 224296

End: 225486

Strand: Direct

Name: anmK

Synonym: TTE0217

Alternate gene names: 20806743

Gene position: 224296-225486 (Clockwise)

Preceding gene: 20806742

Following gene: 20806744

Centisome position: 8.34

GC content: 37.11

Gene sequence:

>1191_bases
ATGGATAGGTTATTGCGTATTTACAATAAAGAAGAAAGATTAGTGGTTGGGTTAATGTCCGGTACTTCTGCTGACGGGAT
TGATGCTGCTCTTGTGAAGGTCAAAGGGAGAGGTTTAGATACAAAGGTTGAACTTTTAGAATTCGAAAAGTTTCCGTACG
AAGAGGAAGTGCAAAAGAAGATATTTGAGCTTTTTGACCCCCATACTGGAACTGTTGAGAAGATATGCCATATGAATTTT
TTACTCGGTGAACTGTTTGCAGAAGCTACCTTAAAACTCATTAAAAAAGCAGGTTTAACCCCGAAAGATATAGATTTAAT
AGGGTCTCACGGGCAGACCATATACCATATTCCTAACTTTATTGAAGATATGGGATATAAAGTCCGTTCTACTCTTCAAA
TAGGGGAACCAGCAGTAATAGCTGAAAGAACTGGAATTGTAACAGTGGCTGATTTTAGGGTAAGAGATGTAGCTGCAGGA
GGGCAAGGAGCTCCTTTAGTACCTTACACTGAATATATCTTGTATAGGTCACCAAATGAAACAATAGCCTTACAAAATAT
AGGTGGAATTGGCAATGTTACTGTTTTGCCTAAAGGAGGTAGTATAGAAGACGTAATTGCATTTGATACAGGTCCTGGAA
ACATGGTGATAGATGAAGTTGTGAAGAGGATTACTCATGGGAAAATGAATTTCGACAAAGATGGTGAATTAGCATCTCGC
GGGAAAGTAAATGAAGAATTTTTAGCAGAGCTGTTAAAAGATGAATTTTTTAAAATGAAGCCTCCAAAGACCACTGGCAG
AGAGCATTTTGGGAAAAATTATGTGGATAATTTGATGAAAAAGGCTTCCTACTTGGAAATAGATAAATACGATTTGGTTG
CTACTGTTACAGCTTTAACTGCTTATTCAGTGGTGAGAAGCTACGAAAAGTTTATATTTCCCTACTACAAAGTTGACAAA
GTAGTAATAGGAGGTGGAGGAAGTTTCAACAAAACCCTTGTACAAATGATAAAAAAACAGTTGCCTCAGGTTAGGGTAAT
AACGCAAGAAGACATAGGATTTAATAGCGATGCCAAAGAAGCTGTTGCTTTTGCAATCCTTGCAAGTGAGACTATAAATG
GCAATTTTAACAATATTCCAAAAGCAACAGGAGCAAAACATCCGGTAGTAATGGGAAAAATTTCTTTATAG

Upstream 100 bases:

>100_bases
ATCCTAAAGCGAATATAAAAAAGCTAGATAAAGATGCGTCTTATGGAGCTGCTATTTTAGCGTTGAATTTTTTAAAAGAA
CGATGAGAGAGGAAAGTGCG

Downstream 100 bases:

>100_bases
TAGGTGGTGTGGCAATGGGTATTGACTATCTGCCGTTGGCAAGAGATAAGGGAGAAGAGATTGTAAGGCTATGGAATAAA
GAATTGGGTAAAGAATTTCC

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MDRLLRIYNKEERLVVGLMSGTSADGIDAALVKVKGRGLDTKVELLEFEKFPYEEEVQKKIFELFDPHTGTVEKICHMNF
LLGELFAEATLKLIKKAGLTPKDIDLIGSHGQTIYHIPNFIEDMGYKVRSTLQIGEPAVIAERTGIVTVADFRVRDVAAG
GQGAPLVPYTEYILYRSPNETIALQNIGGIGNVTVLPKGGSIEDVIAFDTGPGNMVIDEVVKRITHGKMNFDKDGELASR
GKVNEEFLAELLKDEFFKMKPPKTTGREHFGKNYVDNLMKKASYLEIDKYDLVATVTALTAYSVVRSYEKFIFPYYKVDK
VVIGGGGSFNKTLVQMIKKQLPQVRVITQEDIGFNSDAKEAVAFAILASETINGNFNNIPKATGAKHPVVMGKISL

Sequences:

>Translated_396_residues
MDRLLRIYNKEERLVVGLMSGTSADGIDAALVKVKGRGLDTKVELLEFEKFPYEEEVQKKIFELFDPHTGTVEKICHMNF
LLGELFAEATLKLIKKAGLTPKDIDLIGSHGQTIYHIPNFIEDMGYKVRSTLQIGEPAVIAERTGIVTVADFRVRDVAAG
GQGAPLVPYTEYILYRSPNETIALQNIGGIGNVTVLPKGGSIEDVIAFDTGPGNMVIDEVVKRITHGKMNFDKDGELASR
GKVNEEFLAELLKDEFFKMKPPKTTGREHFGKNYVDNLMKKASYLEIDKYDLVATVTALTAYSVVRSYEKFIFPYYKVDK
VVIGGGGSFNKTLVQMIKKQLPQVRVITQEDIGFNSDAKEAVAFAILASETINGNFNNIPKATGAKHPVVMGKISL
>Mature_396_residues
MDRLLRIYNKEERLVVGLMSGTSADGIDAALVKVKGRGLDTKVELLEFEKFPYEEEVQKKIFELFDPHTGTVEKICHMNF
LLGELFAEATLKLIKKAGLTPKDIDLIGSHGQTIYHIPNFIEDMGYKVRSTLQIGEPAVIAERTGIVTVADFRVRDVAAG
GQGAPLVPYTEYILYRSPNETIALQNIGGIGNVTVLPKGGSIEDVIAFDTGPGNMVIDEVVKRITHGKMNFDKDGELASR
GKVNEEFLAELLKDEFFKMKPPKTTGREHFGKNYVDNLMKKASYLEIDKYDLVATVTALTAYSVVRSYEKFIFPYYKVDK
VVIGGGGSFNKTLVQMIKKQLPQVRVITQEDIGFNSDAKEAVAFAILASETINGNFNNIPKATGAKHPVVMGKISL

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=379, Percent_Identity=35.6200527704486, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_THETN (Q8RD30)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_621914.1
- ProteinModelPortal:   Q8RD30
- SMR:   Q8RD30
- GeneID:   997385
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0217
- NMPDR:   fig|273068.3.peg.887
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- ProtClustDB:   PRK09585
- BioCyc:   TTEN273068:TTE0217-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 43805; Mature: 43805

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLLRIYNKEERLVVGLMSGTSADGIDAALVKVKGRGLDTKVELLEFEKFPYEEEVQKK
CCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHH
IFELFDPHTGTVEKICHMNFLLGELFAEATLKLIKKAGLTPKDIDLIGSHGQTIYHIPNF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCEEEECHHH
IEDMGYKVRSTLQIGEPAVIAERTGIVTVADFRVRDVAAGGQGAPLVPYTEYILYRSPNE
HHHCCHHHHHEEECCCCEEEEECCCEEEEECCEEEEECCCCCCCCCCCCEEEEEEECCCC
TIALQNIGGIGNVTVLPKGGSIEDVIAFDTGPGNMVIDEVVKRITHGKMNFDKDGELASR
EEEEEECCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHC
GKVNEEFLAELLKDEFFKMKPPKTTGREHFGKNYVDNLMKKASYLEIDKYDLVATVTALT
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AYSVVRSYEKFIFPYYKVDKVVIGGGGSFNKTLVQMIKKQLPQVRVITQEDIGFNSDAKE
HHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
AVAFAILASETINGNFNNIPKATGAKHPVVMGKISL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MDRLLRIYNKEERLVVGLMSGTSADGIDAALVKVKGRGLDTKVELLEFEKFPYEEEVQKK
CCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCHHHHHHH
IFELFDPHTGTVEKICHMNFLLGELFAEATLKLIKKAGLTPKDIDLIGSHGQTIYHIPNF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCEEEECHHH
IEDMGYKVRSTLQIGEPAVIAERTGIVTVADFRVRDVAAGGQGAPLVPYTEYILYRSPNE
HHHCCHHHHHEEECCCCEEEEECCCEEEEECCEEEEECCCCCCCCCCCCEEEEEEECCCC
TIALQNIGGIGNVTVLPKGGSIEDVIAFDTGPGNMVIDEVVKRITHGKMNFDKDGELASR
EEEEEECCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHC
GKVNEEFLAELLKDEFFKMKPPKTTGREHFGKNYVDNLMKKASYLEIDKYDLVATVTALT
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AYSVVRSYEKFIFPYYKVDKVVIGGGGSFNKTLVQMIKKQLPQVRVITQEDIGFNSDAKE
HHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
AVAFAILASETINGNFNNIPKATGAKHPVVMGKISL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336