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The map label for this gene is Tdk [H]

Identifier: 20806669

GI number: 20806669

Start: 139249

End: 139830

Strand: Direct

Name: Tdk [H]

Synonym: TTE0140

Alternate gene names: 20806669

Gene position: 139249-139830 (Clockwise)

Preceding gene: 20806668

Following gene: 20806670

Centisome position: 5.18

GC content: 39.86

Gene sequence:

>582_bases
ATGATATACGGTTCACTGGACCACGGTTTTATAGAGGTTATAGTAGGTCCTATGTTCAGTGGAAAAAGCGAAGAGCTGAT
AAGAAGAATTAGGAGAGCCCAGATAGCAAAGCAAAAAGTACAGGTCTTTAAGCCTGCCATTGATGACAGGTATTCTATTG
ACAAAGTGGTATCTCATAACGGAAGCAGTATAAATGCCATCTCTGTCACAAAGGCATCAGAGATATTGGACCTTTTAGAA
GAAGATACACAGGTGGTGGCAATAGATGAGATTCAATTTTTTGACCATTCTCTTGTTGATGTGGTAAGAGAAATAGCTGA
TATGGGGAAAAGGGTTATATGTGCGGGACTGGATATGGATTTTAGGGGAGAGCCTTTTGGAGTTACTCCAGATATAATGG
CGATTGCTGAGTCTGTAGATAAATTAACTGCTATTTGTGTTAAATGTGGCAATCCTGCAACGAGAACACAAAGACTTATA
AATGGTAAACCTGCTAAATATGATGATCCAATTATTTTAGTAGGAGCCCATGAGACTTACGAAGCAAGGTGCAGAAAGTG
CCACGAAGTTCCGCGTACATAA

Upstream 100 bases:

>100_bases
AGAAAGAGATTTAATTTAGAGGAAAAATAATTTGGGGGTTAGAGTGTAAAAGACTCTAACCTTTTGTTTTTAATTTGACA
TTAAAAGAAAGGTGGTTTTT

Downstream 100 bases:

>100_bases
AGATGGGGGTGCAGTGATGAAGAAAACTGATATAGGCGGGCAGGCAGTAATTGAAGGAGTTATGATGAGGGGACATAAAA
GCTATGCTATAGCTTTGAGA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIRRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGSSINAISVTKASEILDLLE
EDTQVVAIDEIQFFDHSLVDVVREIADMGKRVICAGLDMDFRGEPFGVTPDIMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT

Sequences:

>Translated_193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIRRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGSSINAISVTKASEILDLLE
EDTQVVAIDEIQFFDHSLVDVVREIADMGKRVICAGLDMDFRGEPFGVTPDIMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT
>Mature_193_residues
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIRRAQIAKQKVQVFKPAIDDRYSIDKVVSHNGSSINAISVTKASEILDLLE
EDTQVVAIDEIQFFDHSLVDVVREIADMGKRVICAGLDMDFRGEPFGVTPDIMAIAESVDKLTAICVKCGNPATRTQRLI
NGKPAKYDDPIILVGAHETYEARCRKCHEVPRT

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=186, Percent_Identity=40.3225806451613, Blast_Score=120, Evalue=7e-28,
Organism=Escherichia coli, GI1787490, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543396, Length=183, Percent_Identity=36.0655737704918, Blast_Score=106, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21459; Mature: 21459

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIRRAQIAKQKVQVFKPAIDDRYSIDKVVSHN
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSSINAISVTKASEILDLLEEDTQVVAIDEIQFFDHSLVDVVREIADMGKRVICAGLDMD
CCCEEEEEHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FRGEPFGVTPDIMAIAESVDKLTAICVKCGNPATRTQRLINGKPAKYDDPIILVGAHETY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHH
EARCRKCHEVPRT
HHHHHHHHCCCCC
>Mature Secondary Structure
MIYGSLDHGFIEVIVGPMFSGKSEELIRRIRRAQIAKQKVQVFKPAIDDRYSIDKVVSHN
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSSINAISVTKASEILDLLEEDTQVVAIDEIQFFDHSLVDVVREIADMGKRVICAGLDMD
CCCEEEEEHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FRGEPFGVTPDIMAIAESVDKLTAICVKCGNPATRTQRLINGKPAKYDDPIILVGAHETY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHH
EARCRKCHEVPRT
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA