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The map label for this gene is Mrp [H]

Identifier: 20806648

GI number: 20806648

Start: 120891

End: 121967

Strand: Direct

Name: Mrp [H]

Synonym: TTE0119

Alternate gene names: 20806648

Gene position: 120891-121967 (Clockwise)

Preceding gene: 20806643

Following gene: 20806650

Centisome position: 4.5

GC content: 41.32

Gene sequence:

>1077_bases
TTGATTACAAAAGAGCAGATATTATCGGCACTAAAAAAGGTGTATGACCCAGAACTTAGAAGAAATGTAGTAGATTTGGG
GATGGTTAAAAATATTGAGATAGAAGGGGATAAGGTTACAGTTGACATAAATTTGACCGTGAAAGGCTGTCCTCTTCGCG
ACCAGATAAAAAACAATGCTATCAAAGAAATATCAAAAATAGAAGGAGTTTCAGAAGTTGTGGTAAACATTGGGGCCATG
ACGGAAGAGGAAAGGCAGGATTTAGCAAGAAGGCTCAAGGAGGAGAAGAAAAACCTTTTCGAGAATACCAGAGTTATAGT
GGTAGGAAGCGGCAAGGGTGGTGTAGGCAAATCCACTGTTGCAGTAAATTTGGCTGTTGCTCTTTCAAGGTTAGGCTTTG
AAGTAGGACTTTTGGATGCGGATATTTTGGGTTCTAGTGTGCCAAGGCTTTTGGGCATTGTAGGAGAAAAGCCTTACGCT
TTGGACGAACACACTGTCTTGCCTATTGAAAGATTTGGCCTGAAAATTATATCTATGGGAAATTTTGTCGATGAAGATAC
GCCTTTGATATGGAGAGGGCCCCTTTTGACAGGAGTAATAGACCAGTTTTTTAATGAGGTTTTATGGGGAGATTTGGATT
ACTTGGTATTAGATTTGCCGCCAGGCACGGGAGACATACCCCTTACTGTAATGCAAAGGCTGCCTGAGGCAAAATTTATT
CTTGTTACTACTCCTCAAGCATCTGCCTCCCACGTTGCAGGAAGAATAGGACATATGGCGAAAAAGGTCAATGTAGAGGT
TATAGGGATTGTAGAAAACATGTCTTATTTTGAGTGTCCTAAGTGTGGCGAGAGGTACAATATCTTCGGAGAAGGAGAGA
CTGAAAAGCTGGCAGAAGCTTTGCAGACAGAAATACTGGCGAGAATCCCAATAGTGGTGAAGATAAGGGAGTTAAGCGAT
GAAGGCATTCCACCTGCTCTTGATGACACTGAAGAAGGAGCAATCTATGTTGAATTAGCTGAGAAAATTGTAGAAAAAGT
AAGGCCTTTAAGGCATGAAAAAGAGCCCCTAAAATAA

Upstream 100 bases:

>100_bases
ATTATTCGAATTGAAGAAAATTTTTAGGGGTATTCTATTAGTAATGATTATATATTATAATATAGTTGTCAACAAAAAAG
TACCAATAGGGGGTATAAAA

Downstream 100 bases:

>100_bases
GGGGGCTCTCAGACTGTTGACAAAGTCCTTCTTATTTAGGTGGCATTTTGTGTTAATGCTCCAGAGTTGCAAAGCGACTA
AACTAAGGCTCACTTTTCGG

Product: chromosome partitioning ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MITKEQILSALKKVYDPELRRNVVDLGMVKNIEIEGDKVTVDINLTVKGCPLRDQIKNNAIKEISKIEGVSEVVVNIGAM
TEEERQDLARRLKEEKKNLFENTRVIVVGSGKGGVGKSTVAVNLAVALSRLGFEVGLLDADILGSSVPRLLGIVGEKPYA
LDEHTVLPIERFGLKIISMGNFVDEDTPLIWRGPLLTGVIDQFFNEVLWGDLDYLVLDLPPGTGDIPLTVMQRLPEAKFI
LVTTPQASASHVAGRIGHMAKKVNVEVIGIVENMSYFECPKCGERYNIFGEGETEKLAEALQTEILARIPIVVKIRELSD
EGIPPALDDTEEGAIYVELAEKIVEKVRPLRHEKEPLK

Sequences:

>Translated_358_residues
MITKEQILSALKKVYDPELRRNVVDLGMVKNIEIEGDKVTVDINLTVKGCPLRDQIKNNAIKEISKIEGVSEVVVNIGAM
TEEERQDLARRLKEEKKNLFENTRVIVVGSGKGGVGKSTVAVNLAVALSRLGFEVGLLDADILGSSVPRLLGIVGEKPYA
LDEHTVLPIERFGLKIISMGNFVDEDTPLIWRGPLLTGVIDQFFNEVLWGDLDYLVLDLPPGTGDIPLTVMQRLPEAKFI
LVTTPQASASHVAGRIGHMAKKVNVEVIGIVENMSYFECPKCGERYNIFGEGETEKLAEALQTEILARIPIVVKIRELSD
EGIPPALDDTEEGAIYVELAEKIVEKVRPLRHEKEPLK
>Mature_358_residues
MITKEQILSALKKVYDPELRRNVVDLGMVKNIEIEGDKVTVDINLTVKGCPLRDQIKNNAIKEISKIEGVSEVVVNIGAM
TEEERQDLARRLKEEKKNLFENTRVIVVGSGKGGVGKSTVAVNLAVALSRLGFEVGLLDADILGSSVPRLLGIVGEKPYA
LDEHTVLPIERFGLKIISMGNFVDEDTPLIWRGPLLTGVIDQFFNEVLWGDLDYLVLDLPPGTGDIPLTVMQRLPEAKFI
LVTTPQASASHVAGRIGHMAKKVNVEVIGIVENMSYFECPKCGERYNIFGEGETEKLAEALQTEILARIPIVVKIRELSD
EGIPPALDDTEEGAIYVELAEKIVEKVRPLRHEKEPLK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=270, Percent_Identity=40, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI6912540, Length=234, Percent_Identity=38.034188034188, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI118572611, Length=259, Percent_Identity=35.5212355212355, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI87082045, Length=346, Percent_Identity=36.9942196531792, Blast_Score=214, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI25143050, Length=253, Percent_Identity=34.3873517786561, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322188, Length=223, Percent_Identity=40.3587443946188, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321347, Length=224, Percent_Identity=36.1607142857143, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221511043, Length=268, Percent_Identity=38.0597014925373, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24667611, Length=254, Percent_Identity=41.3385826771654, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI19921440, Length=258, Percent_Identity=35.6589147286822, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 39521; Mature: 39521

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKEQILSALKKVYDPELRRNVVDLGMVKNIEIEGDKVTVDINLTVKGCPLRDQIKNNA
CCCHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEEEECCCCHHHHHHHH
IKEISKIEGVSEVVVNIGAMTEEERQDLARRLKEEKKNLFENTRVIVVGSGKGGVGKSTV
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHH
AVNLAVALSRLGFEVGLLDADILGSSVPRLLGIVGEKPYALDEHTVLPIERFGLKIISMG
HHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECC
NFVDEDTPLIWRGPLLTGVIDQFFNEVLWGDLDYLVLDLPPGTGDIPLTVMQRLPEAKFI
CCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEE
LVTTPQASASHVAGRIGHMAKKVNVEVIGIVENMSYFECPKCGERYNIFGEGETEKLAEA
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHH
LQTEILARIPIVVKIRELSDEGIPPALDDTEEGAIYVELAEKIVEKVRPLRHEKEPLK
HHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MITKEQILSALKKVYDPELRRNVVDLGMVKNIEIEGDKVTVDINLTVKGCPLRDQIKNNA
CCCHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCEEEEEEEEEEECCCCHHHHHHHH
IKEISKIEGVSEVVVNIGAMTEEERQDLARRLKEEKKNLFENTRVIVVGSGKGGVGKSTV
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHH
AVNLAVALSRLGFEVGLLDADILGSSVPRLLGIVGEKPYALDEHTVLPIERFGLKIISMG
HHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECC
NFVDEDTPLIWRGPLLTGVIDQFFNEVLWGDLDYLVLDLPPGTGDIPLTVMQRLPEAKFI
CCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEE
LVTTPQASASHVAGRIGHMAKKVNVEVIGIVENMSYFECPKCGERYNIFGEGETEKLAEA
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHH
LQTEILARIPIVVKIRELSDEGIPPALDDTEEGAIYVELAEKIVEKVRPLRHEKEPLK
HHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]