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The map label for this gene is TtdA [C]

Identifier: 20806607

GI number: 20806607

Start: 81579

End: 82421

Strand: Direct

Name: TtdA [C]

Synonym: TTE0075

Alternate gene names: 20806607

Gene position: 81579-82421 (Clockwise)

Preceding gene: 20806606

Following gene: 20806608

Centisome position: 3.03

GC content: 39.26

Gene sequence:

>843_bases
TTGAGGGAGATAAAAGCTAGTCAAATTGTGGAAGTTGTCAAAAAGCTGTGTATTGAAGCGAATTATAATTTACCGGATGA
TATATTAAAAGGGCTCAAAATCCGGAAGAAGGAGGAAAAAAGTCCTTTAGGCCAAAAAATTCTTGAAGATATAATTTTAA
ATGCTGAAATAGCTATGCAAGAGAAAATGGCTATATGTCAGGATACAGGAATGGCCGTGGTTTTTGTAGAGATAGGACAA
GAAGTACGCGTTGTAGATGGAGATTTGGAAGAGGCTATAAATGAAGGAGTGAGATTGGGTTATAAAGAGGGATATTTGAG
AAAGTCTGTTGTGAAAAGCCCTATAGAAAGAATTAACACAGATGACAACACTCCTGCTATAATACATTATCGTGTGTGTA
GAGGAGATAGACTCATTATAACTGTAATGCCAAAAGGAGCTGGCAGCGAAAATATGAGTGCTTTGAAGATGTTAAAGCCT
TCAGATGATTTAGAAGGGGTAAAAAGATTTGTAATAGAGACTGTGGAAAAATCCGGTCCTAACGCTTGTCCTCCTCTGAT
TGTGGGGGTTGGTCTTGGAGGAGATTTTGAATATGCAGCCTATCTAGCGAAAAAAGCACTGTTGAGGAAAGTCGGCGAAA
GGCATCAGGATATTTTAATTGCTAGGTTGGAAGAAGAGCTTTTAAATGAGATAAACTCTTTAGGCATTGGGCCGATGGGC
CTTGGAGGGACTACTACTGCCCTAGATGTCCACATAGAAGTATATCCTACCCACATTGCTTCTTTGCCTGTTGCAGTAAA
TTTGGGATGCCATGCTACGAGACACGCTACTTTTGTATTATAA

Upstream 100 bases:

>100_bases
ATTATAAGAGATTTTCAAAGAAATTGCAAAATTGATATTAAAAACAGCGCAAAAAAATAGTATCATAAATCATATAAAAG
GTAATTTAGGGGTGAAAGTT

Downstream 100 bases:

>100_bases
TTATGTTTGGAGGGAAAACATGTACAGAAAATTAAATACACCTTTACTAGATGAAGTAACAGTACAATTGAAAGCAGGGG
ATTTGATTTTGCTCTCAGGA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVEIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTDDNTPAIIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDDLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL

Sequences:

>Translated_280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVEIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTDDNTPAIIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDDLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
>Mature_280_residues
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQEKMAICQDTGMAVVFVEIGQ
EVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINTDDNTPAIIHYRVCRGDRLIITVMPKGAGSENMSALKMLKP
SDDLEGVKRFVIETVEKSGPNACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=283, Percent_Identity=33.2155477031802, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1790564, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787897, Length=241, Percent_Identity=31.1203319502075, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30720; Mature: 30720

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHH
EKMAICQDTGMAVVFVEIGQEVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINT
HHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
DDNTPAIIHYRVCRGDRLIITVMPKGAGSENMSALKMLKPSDDLEGVKRFVIETVEKSGP
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
NACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
CCCCCEEEEEEEEEEECHHHCCCEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MREIKASQIVEVVKKLCIEANYNLPDDILKGLKIRKKEEKSPLGQKILEDIILNAEIAMQ
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCHHHHH
EKMAICQDTGMAVVFVEIGQEVRVVDGDLEEAINEGVRLGYKEGYLRKSVVKSPIERINT
HHHHHHHCCCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
DDNTPAIIHYRVCRGDRLIITVMPKGAGSENMSALKMLKPSDDLEGVKRFVIETVEKSGP
CCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
NACPPLIVGVGLGGDFEYAAYLAKKALLRKVGERHQDILIARLEEELLNEINSLGIGPMG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGGTTTALDVHIEVYPTHIASLPVAVNLGCHATRHATFVL
CCCCCEEEEEEEEEEECHHHCCCEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]