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The map label for this gene is tmk [H]

Identifier: 203284688

GI number: 203284688

Start: 847980

End: 848588

Strand: Reverse

Name: tmk [H]

Synonym: BDU_800

Alternate gene names: 203284688

Gene position: 848588-847980 (Counterclockwise)

Preceding gene: 203284692

Following gene: 203284687

Centisome position: 91.08

GC content: 25.29

Gene sequence:

>609_bases
GTGACTAAGATCCTAAAAAATTTTTATTGTATAGAAGGAATTGATGGAAGCGGCAAAACAAGTATAATCCAAAAATTACA
AAAAATCTGTAACAATAAAATGAAATACCATTTTACAAAAGAACCATCAACAGGAATAATTGGCAAACTCATAAGAAAAC
AACTGACCAACTTTAAAAATCCCTTACGAAAAGTATCATTAGCACATTTATACGTTGCAGATAGATACGAACATTTATAT
AATATACAAAATGGAATAATAGCAATACTAAATAAAAATCAAACAAAAGTAATAAGCGATAGATATTTATTCTCATCTAT
AGCATATCAAGGAGAATTAGGGTATAAACTAAATAAAGATTTCCCATTACCTGAAAAACTTTTTTTTATAAAAACAGACC
CCAATATAGCATTTAAACGTATTCAAAAAAATAGAACACAAGCGGATCTTTTTGAATTTGAAGAAGCTAAATTTAAAGAA
ATAAATTCTAGATACATGGAAATGTTTCAAATTTTTAATCAACTAATTGATATTGTATATATTGAAAACTCAAGTGAACA
CGATCTTGAAATAAGTGCAAGGAAAATTTTTGATTTAATAAAATTTTAA

Upstream 100 bases:

>100_bases
TTATTCCTTATAAAAAACAAATTCATAGATCTATTAATATATATTATATAATATTTACAGTAAGCATCTAATTACTAAAA
TATCTAAGGAGATAATTTTT

Downstream 100 bases:

>100_bases
CATCTAGTATAACAAAAGGAAGGATACAAAACATGTTTCATAATAACTTTTTTGTATTATATTTAATAGTACTTTCAATT
TTACTCATAATTAACGTCAA

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKLIRKQLTNFKNPLRKVSLAHLYVADRYEHLY
NIQNGIIAILNKNQTKVISDRYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPNIAFKRIQKNRTQADLFEFEEAKFKE
INSRYMEMFQIFNQLIDIVYIENSSEHDLEISARKIFDLIKF

Sequences:

>Translated_202_residues
MTKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKLIRKQLTNFKNPLRKVSLAHLYVADRYEHLY
NIQNGIIAILNKNQTKVISDRYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPNIAFKRIQKNRTQADLFEFEEAKFKE
INSRYMEMFQIFNQLIDIVYIENSSEHDLEISARKIFDLIKF
>Mature_201_residues
TKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKLIRKQLTNFKNPLRKVSLAHLYVADRYEHLYN
IQNGIIAILNKNQTKVISDRYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPNIAFKRIQKNRTQADLFEFEEAKFKEI
NSRYMEMFQIFNQLIDIVYIENSSEHDLEISARKIFDLIKF

Specific function: Phosphorylation Of Dtmp To Form Dtdp In Both De Novo And Salvage Pathways Of Dttp Synthesis. [C]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018095
- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 23823; Mature: 23692

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS01331 THYMIDYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKLIRKQLTNFKN
CCHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
PLRKVSLAHLYVADRYEHLYNIQNGIIAILNKNQTKVISDRYLFSSIAYQGELGYKLNKD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCC
FPLPEKLFFIKTDPNIAFKRIQKNRTQADLFEFEEAKFKEINSRYMEMFQIFNQLIDIVY
CCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IENSSEHDLEISARKIFDLIKF
ECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKLIRKQLTNFKN
CHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
PLRKVSLAHLYVADRYEHLYNIQNGIIAILNKNQTKVISDRYLFSSIAYQGELGYKLNKD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCC
FPLPEKLFFIKTDPNIAFKRIQKNRTQADLFEFEEAKFKEINSRYMEMFQIFNQLIDIVY
CCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IENSSEHDLEISARKIFDLIKF
ECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]