Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 203284625

GI number: 203284625

Start: 781684

End: 783258

Strand: Reverse

Name: pgi [H]

Synonym: BDU_733

Alternate gene names: 203284625

Gene position: 783258-781684 (Counterclockwise)

Preceding gene: 203284626

Following gene: 203284624

Centisome position: 84.07

GC content: 28.44

Gene sequence:

>1575_bases
ATGATTCATTATAATGACCTTAATAAGCTTAAAAGTTTTCAAGAATTAAAACAAATGAATCCCGAAAAACTAAAGACAGT
ATTAAATGAAAACAGAATTCAAGAATATGACATCAAAATAGAAGGAAATCACGTACATTATAACTATGCTACAAAACAAA
TCAATGAAGCTCATTTAAAGTTATTTCAAAATTTAAGCGATGAAGCAAATCTAATAGAAAAGTATAAAGAAATCATTAAT
GGAAAACATATTAATCTTAGTGAAAATAGAAAAGTTTTACATCACTTAACAAGAGGACAACTTGGTACAACAGTTACAGA
TAACAATGAAAATATGCGAGAATTTTTTGAAAGAGAACTTCATAAAATTTTTGAATTTGCACAAAAAATACAAAATGGTA
CTATTAAAAATACAAATGGAAAAGTTTTTAAAAATGTCGTACAAATTGGTATTGGGGGTTCAAGTCTTGGCCCAAAAGCA
CTATACACTACAATTAAAAACTATGCTCAACAAAAAAATTTATACAAAATGAAAGCATATTTTATTTCAAATGTTGACCC
AGATGAAGCAGAAGAGGTTTTAAGCGAAATAAATCTTCAAGAAACTTTATTTATTGTCGTATCAAAAAGTGGAACTACAC
TAGAAACATCATCTAATATGCAATTCTTAATTAAAAAATTAAAAGATAATGGAATTGAAGAATATAAAAAACAAATTATA
ATCATTACATCACAAGGAAGTATGTTGGCACTCGAAAAAGGATACCTTGAGTACTTTTTTATGCATGATTCAATTGGTGG
AAGATTTTCACCAACATCAGCTGTAGGGCTTGCTCTAATAACCCTTTGCTTCACAGAAGATATTACAAAAGAAATATTAA
AGGGAGCTCATGAGGCTGACAAACAGGCACTAAATAAAAATATAAGAGAAAATGCACCCCTTCTAGCATCAATAATTAGT
ATATATGAAAGCAATATACTAAATTATAGCAGCAACTGTATTATTGCATATTCAAAAGCAATGGAAAACTTTTATCTTCA
TTTACAACAACTTGAAATGGAAAGCAATGGAAAAAGCGTAAACAGATTTGGGGAACAAATTGACTATAAAACAGTAAGAA
TAATTTGGGGAGGAATTGGAACAGATGTGCAACATTCATTCTTTCAAATGCTTCATCAAGGAACAGAAATAGTACCAATG
GATTTAATAGGATTTAGCCAATCCCAATTAAAGCAAGATGTTTCTTTAGATGGAACATCAAGTAATGATAAACTAAAAGC
AAATCTAATAGCTCAAATAATTGCATTTGCTATTGGAAAAGAAAATATAAATCAAAATAAAAGTTTTAAAGGAGAGAGAC
CCTCTGCATTAATATACTCTAAAGAGCTCACTCCTTATACAATAGGTGCGATACTCTCTCATTACGAAAATAAAGTAATG
TTTGAAGGATTCCTACTAAATATCAATTCATTTGATCAAGAAGGAGTTCAACTAGGCAAAATTATTGCTAACAAAATTTT
AAAGGACGATAATTCACAAGATAAAATAATCAAATCTTATGATAGACTATTTTAA

Upstream 100 bases:

>100_bases
ATTTATAAAAAAAATAATAATAAAAATAAAAAAAATAATAATAAAAATAAAAAAACAAAATTAAATTTAAATACACAAAA
AAACTATTGGAGGATGCTTA

Downstream 100 bases:

>100_bases
CAAAAAAATAATTATTTTAAATCTATAATTAAGAGGCCAAATCATGAACATGACAATAACATATGTAATATTAAATGTTA
CAATAACGTTTATATTAATA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MIHYNDLNKLKSFQELKQMNPEKLKTVLNENRIQEYDIKIEGNHVHYNYATKQINEAHLKLFQNLSDEANLIEKYKEIIN
GKHINLSENRKVLHHLTRGQLGTTVTDNNENMREFFERELHKIFEFAQKIQNGTIKNTNGKVFKNVVQIGIGGSSLGPKA
LYTTIKNYAQQKNLYKMKAYFISNVDPDEAEEVLSEINLQETLFIVVSKSGTTLETSSNMQFLIKKLKDNGIEEYKKQII
IITSQGSMLALEKGYLEYFFMHDSIGGRFSPTSAVGLALITLCFTEDITKEILKGAHEADKQALNKNIRENAPLLASIIS
IYESNILNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSVNRFGEQIDYKTVRIIWGGIGTDVQHSFFQMLHQGTEIVPM
DLIGFSQSQLKQDVSLDGTSSNDKLKANLIAQIIAFAIGKENINQNKSFKGERPSALIYSKELTPYTIGAILSHYENKVM
FEGFLLNINSFDQEGVQLGKIIANKILKDDNSQDKIIKSYDRLF

Sequences:

>Translated_524_residues
MIHYNDLNKLKSFQELKQMNPEKLKTVLNENRIQEYDIKIEGNHVHYNYATKQINEAHLKLFQNLSDEANLIEKYKEIIN
GKHINLSENRKVLHHLTRGQLGTTVTDNNENMREFFERELHKIFEFAQKIQNGTIKNTNGKVFKNVVQIGIGGSSLGPKA
LYTTIKNYAQQKNLYKMKAYFISNVDPDEAEEVLSEINLQETLFIVVSKSGTTLETSSNMQFLIKKLKDNGIEEYKKQII
IITSQGSMLALEKGYLEYFFMHDSIGGRFSPTSAVGLALITLCFTEDITKEILKGAHEADKQALNKNIRENAPLLASIIS
IYESNILNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSVNRFGEQIDYKTVRIIWGGIGTDVQHSFFQMLHQGTEIVPM
DLIGFSQSQLKQDVSLDGTSSNDKLKANLIAQIIAFAIGKENINQNKSFKGERPSALIYSKELTPYTIGAILSHYENKVM
FEGFLLNINSFDQEGVQLGKIIANKILKDDNSQDKIIKSYDRLF
>Mature_524_residues
MIHYNDLNKLKSFQELKQMNPEKLKTVLNENRIQEYDIKIEGNHVHYNYATKQINEAHLKLFQNLSDEANLIEKYKEIIN
GKHINLSENRKVLHHLTRGQLGTTVTDNNENMREFFERELHKIFEFAQKIQNGTIKNTNGKVFKNVVQIGIGGSSLGPKA
LYTTIKNYAQQKNLYKMKAYFISNVDPDEAEEVLSEINLQETLFIVVSKSGTTLETSSNMQFLIKKLKDNGIEEYKKQII
IITSQGSMLALEKGYLEYFFMHDSIGGRFSPTSAVGLALITLCFTEDITKEILKGAHEADKQALNKNIRENAPLLASIIS
IYESNILNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSVNRFGEQIDYKTVRIIWGGIGTDVQHSFFQMLHQGTEIVPM
DLIGFSQSQLKQDVSLDGTSSNDKLKANLIAQIIAFAIGKENINQNKSFKGERPSALIYSKELTPYTIGAILSHYENKVM
FEGFLLNINSFDQEGVQLGKIIANKILKDDNSQDKIIKSYDRLF

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=533, Percent_Identity=29.4559099437148, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI296080693, Length=533, Percent_Identity=27.2045028142589, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1790457, Length=496, Percent_Identity=35.2822580645161, Blast_Score=271, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI71996708, Length=500, Percent_Identity=31.2, Blast_Score=250, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71996703, Length=500, Percent_Identity=31.2, Blast_Score=249, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6319673, Length=497, Percent_Identity=31.58953722334, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24651916, Length=534, Percent_Identity=30.3370786516854, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24651914, Length=534, Percent_Identity=30.3370786516854, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17737445, Length=534, Percent_Identity=30.3370786516854, Blast_Score=255, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59707; Mature: 59707

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHYNDLNKLKSFQELKQMNPEKLKTVLNENRIQEYDIKIEGNHVHYNYATKQINEAHLK
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEECCEEEEEHHHHHHHHHHHH
LFQNLSDEANLIEKYKEIINGKHINLSENRKVLHHLTRGQLGTTVTDNNENMREFFEREL
HHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
HKIFEFAQKIQNGTIKNTNGKVFKNVVQIGIGGSSLGPKALYTTIKNYAQQKNLYKMKAY
HHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
FISNVDPDEAEEVLSEINLQETLFIVVSKSGTTLETSSNMQFLIKKLKDNGIEEYKKQII
HHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCHHHHHHHHHHCCHHHHCCEEE
IITSQGSMLALEKGYLEYFFMHDSIGGRFSPTSAVGLALITLCFTEDITKEILKGAHEAD
EEECCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
KQALNKNIRENAPLLASIISIYESNILNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHH
NRFGEQIDYKTVRIIWGGIGTDVQHSFFQMLHQGTEIVPMDLIGFSQSQLKQDVSLDGTS
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHCCCCCCCC
SNDKLKANLIAQIIAFAIGKENINQNKSFKGERPSALIYSKELTPYTIGAILSHYENKVM
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEE
FEGFLLNINSFDQEGVQLGKIIANKILKDDNSQDKIIKSYDRLF
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIHYNDLNKLKSFQELKQMNPEKLKTVLNENRIQEYDIKIEGNHVHYNYATKQINEAHLK
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEECCEEEEEHHHHHHHHHHHH
LFQNLSDEANLIEKYKEIINGKHINLSENRKVLHHLTRGQLGTTVTDNNENMREFFEREL
HHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHH
HKIFEFAQKIQNGTIKNTNGKVFKNVVQIGIGGSSLGPKALYTTIKNYAQQKNLYKMKAY
HHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
FISNVDPDEAEEVLSEINLQETLFIVVSKSGTTLETSSNMQFLIKKLKDNGIEEYKKQII
HHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCHHHHHHHHHHCCHHHHCCEEE
IITSQGSMLALEKGYLEYFFMHDSIGGRFSPTSAVGLALITLCFTEDITKEILKGAHEAD
EEECCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
KQALNKNIRENAPLLASIISIYESNILNYSSNCIIAYSKAMENFYLHLQQLEMESNGKSV
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHH
NRFGEQIDYKTVRIIWGGIGTDVQHSFFQMLHQGTEIVPMDLIGFSQSQLKQDVSLDGTS
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHCCCCCCCC
SNDKLKANLIAQIIAFAIGKENINQNKSFKGERPSALIYSKELTPYTIGAILSHYENKVM
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEE
FEGFLLNINSFDQEGVQLGKIIANKILKDDNSQDKIIKSYDRLF
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]