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The map label for this gene is era

Identifier: 203284558

GI number: 203284558

Start: 711736

End: 712608

Strand: Reverse

Name: era

Synonym: BDU_663

Alternate gene names: 203284558

Gene position: 712608-711736 (Counterclockwise)

Preceding gene: 203284562

Following gene: 203284557

Centisome position: 76.49

GC content: 24.63

Gene sequence:

>873_bases
ATGAAATCAGGATTTGTATCAATCATAGGTAGACCTTCAACAGGGAAATCTACACTTTTAAATTCAATATGTGGACATCA
AATATCAATCACTTCCTCTACACCACAAACAACTAGAAATAAAATAAAAGGAATATTTACAGACAAAAGAGGACAAATCA
TTTTTATAGACACACCAGGATTCCATCTAAGCAAAAAAAATTTCAATATAGCATTAATGAATAACGTATATTCTGCAATT
ATAGAAACAGAATTAATTATCTATGTCATAGACATTCAAGATCAACCTGGAACTGAAGAAAATGAAATATTAACAATCAT
ACAAAGATCCAAAATTAATTTTATAGTGGTCATAAACAAAATTGATATTCACAAAACAAAAGAAAAAGAAATAATGACAT
TTTTAGAAGAAAAAAAAATACAAAAAAACAAAATTATAAAAATCTCTGCTGAAAAGCAAATAAATATTGAGACAATGAAA
GATAAAATTTATGAAAATCTTAATGAAGGACCTCTTTATTATCCAAAAGAATATTATACAGATCAAAAAATAAATTTACG
AATTAGTGAAATAATTAGAGGAGTAACTATTAAAAAACTTAAAGAAGAATTACCATACTCTATATACACAGAAATCGAGA
TCTTAGAAGATAGAGAAAACAAGTTTTTTATTAAGGCAAATATTATTGTAGCTGGAGAGAGTCAAAAGGGAATAATAGTT
GGCAAAGGAGGAAAAGGCATTAAATCAATTGGTGAAGAATCTAGAAAAATAATATCAAAAATACTTGAAAAAAAATGCAA
TTTATTCTTACAAGTAAAATTAAGAAAAAATTGGAATAAAAACGCTAAATTAATTAAAAATTTGATAAATTAA

Upstream 100 bases:

>100_bases
TCAAACCTTAATCCTTGTAACACAATATTTAAAGATAGTATACATTAATTACCATATAAAATATATTAATAATATTAATA
CATTGAAATAGGAAATTAAA

Downstream 100 bases:

>100_bases
TATGATAACATTTTTCAACACTTCTTCATATTGAAATAACAAAAATAGGATGATAAAATTAAGTTTTAACAGAGGAAATA
TTATGAAAACAGCACACTGG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKNFNIALMNNVYSAI
IETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINKIDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMK
DKIYENLNEGPLYYPKEYYTDQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIV
GKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN

Sequences:

>Translated_290_residues
MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKNFNIALMNNVYSAI
IETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINKIDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMK
DKIYENLNEGPLYYPKEYYTDQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIV
GKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN
>Mature_290_residues
MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKNFNIALMNNVYSAI
IETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINKIDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMK
DKIYENLNEGPLYYPKEYYTDQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIV
GKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=324, Percent_Identity=23.1481481481481, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1788919, Length=291, Percent_Identity=36.426116838488, Blast_Score=175, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24646434, Length=303, Percent_Identity=23.4323432343234, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_BORDL (B5RMK6)

Other databases:

- EMBL:   CP000976
- RefSeq:   YP_002222298.1
- EnsemblBacteria:   EBBORT00000001598
- GeneID:   6917889
- GenomeReviews:   CP000976_GR
- KEGG:   bdu:BDU_663
- GeneTree:   EBGT00050000007366
- HOGENOM:   HBG561652
- OMA:   QNATRRK
- ProtClustDB:   PRK00089
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR003593
- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33291; Mature: 33291

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCEEEECCCCCEEEEECCC
FHLSKKNFNIALMNNVYSAIIETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINK
CEEECCCCEEEEHHHHHHHHHCEEEEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEEEE
IDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMKDKIYENLNEGPLYYPKEYYT
EECCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCCCCHHHCC
DQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIV
CCEEEEEHHHHHCCCHHHHHHHHCCEEEEEEEEEEECCCCEEEEEEEEEEECCCCCCEEE
GKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN
ECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCEEEECCCCCEEEEECCC
FHLSKKNFNIALMNNVYSAIIETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVVINK
CEEECCCCEEEEHHHHHHHHHCEEEEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEEEE
IDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMKDKIYENLNEGPLYYPKEYYT
EECCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCCCCHHHCC
DQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIV
CCEEEEEHHHHHCCCHHHHHHHHCCEEEEEEEEEEECCCCEEEEEEEEEEECCCCCCEEE
GKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN
ECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA