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The map label for this gene is cdd [H]

Identifier: 203284519

GI number: 203284519

Start: 657746

End: 658201

Strand: Reverse

Name: cdd [H]

Synonym: BDU_621

Alternate gene names: 203284519

Gene position: 658201-657746 (Counterclockwise)

Preceding gene: 203284521

Following gene: 203284517

Centisome position: 70.65

GC content: 28.73

Gene sequence:

>456_bases
ATGAATGATAATGGACAGGATGCAATTATAAAAGCATTTCAATTAGCTGAAACTGCAAGAAATAACGCATATTCTCCTTA
CTCAAAATTTAAAGTTGGAGCTTGTATTAAAACTAAAGACAATTTATTTTTTCAAGGTTCAAATATTGAAAACGCAAGCT
TTGGAGCAACTAGATGTGCAGAACAAGCTGCAATAATAAACATGATATCATCTGTTGGAGTCCAAAAAATAGATTTCATA
TTAGTCACAACAATCCCAGCAAGTGTCCCATGCGCAATATGTCGTCAAGTAATGTCAGAATTTTTTGAAGAAGATACTAA
AATATTAATAACAGATCCTAATCAATTTAACATGAATAAAAAAGTTTTTAAAATTTACACACTCAACGATCTACTTAAAT
TTCCATTCAATAAAGAAGAACTATCAAAAATATTTAAAGCAAATAAAACAACATGA

Upstream 100 bases:

>100_bases
ATAATTACATCTCATAATTAAACATTTTACAATATTTTAATATAAAATTATAAACATTATGTTATAATTGAATACGTTAT
AAATTCAAGAGGTTTTATAA

Downstream 100 bases:

>100_bases
CATATAAATCTTATATAAAAAATTAAGTCTCAATATCAACTCAAAATACCAAGAGAAACGATAGCCTTTGCAAACTCGCT
TAACTGATTGGATTTCATAG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIENASFGATRCAEQAAIINMISSVGVQKIDFI
LVTTIPASVPCAICRQVMSEFFEEDTKILITDPNQFNMNKKVFKIYTLNDLLKFPFNKEELSKIFKANKTT

Sequences:

>Translated_151_residues
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIENASFGATRCAEQAAIINMISSVGVQKIDFI
LVTTIPASVPCAICRQVMSEFFEEDTKILITDPNQFNMNKKVFKIYTLNDLLKFPFNKEELSKIFKANKTT
>Mature_151_residues
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIENASFGATRCAEQAAIINMISSVGVQKIDFI
LVTTIPASVPCAICRQVMSEFFEEDTKILITDPNQFNMNKKVFKIYTLNDLLKFPFNKEELSKIFKANKTT

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=131, Percent_Identity=33.587786259542, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540514, Length=135, Percent_Identity=40, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=95, Percent_Identity=45.2631578947368, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=137, Percent_Identity=30.6569343065693, Blast_Score=71, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582744, Length=118, Percent_Identity=37.2881355932203, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582741, Length=101, Percent_Identity=39.6039603960396, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920920, Length=113, Percent_Identity=35.3982300884956, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 16940; Mature: 16940

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIENASFGATRCA
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECEEEEECCCEEEECCCCCCCCCCHHHHH
EQAAIINMISSVGVQKIDFILVTTIPASVPCAICRQVMSEFFEEDTKILITDPNQFNMNK
HHHHHHHHHHHCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
KVFKIYTLNDLLKFPFNKEELSKIFKANKTT
EEEEEEEHHHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIENASFGATRCA
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHEEECEEEEECCCEEEECCCCCCCCCCHHHHH
EQAAIINMISSVGVQKIDFILVTTIPASVPCAICRQVMSEFFEEDTKILITDPNQFNMNK
HHHHHHHHHHHCCHHHEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
KVFKIYTLNDLLKFPFNKEELSKIFKANKTT
EEEEEEEHHHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]