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The map label for this gene is pkcI [C]

Identifier: 203284291

GI number: 203284291

Start: 401204

End: 401635

Strand: Reverse

Name: pkcI [C]

Synonym: BDU_373

Alternate gene names: 203284291

Gene position: 401635-401204 (Counterclockwise)

Preceding gene: 203284292

Following gene: 203284286

Centisome position: 43.11

GC content: 26.85

Gene sequence:

>432_bases
TTGGAGGAAATTTTGAGTGATTGTATTTTTTGTAAGATAGTTAAAAATGAAATTTCATGTTATAAGGTTTATGAGGATAA
TTTAATACTTGCTTTTCTTGATATTAATCCTTTAAATATTGGCCATACTCTTGTTATTCCCAAACAACATAGTAATGATA
TTTTAGATGTGAATGATGAACTTGATGGACAACTATTGGGAGTGTGTAAAAAAGTAGCTTTATCTTTAAAAAAATTGGAC
TTTAATATTTGTCAGGGAGTTAATATTTATAGTGCTATTGGTTCTGAGGCAGGACAAGTTATTTTTCACACTCATTTTCA
TGTTATTCCACGATTTCAAGGTGATAATTTAGGTTTTAAGAGAAATTGTAGTATTGAACTTTCAGGAGATGAATATTTAG
ACTTATCTAAAAAAATAAGTAAAAATATTTGA

Upstream 100 bases:

>100_bases
CTGATGTTGTGACCTTAATTGCTTATTTTAATATAGCAAAATTAGTGTTGTCAAATTATTTTTAATAGGTATGCTTTATA
AGCATTAAGATAGAGTTGAT

Downstream 100 bases:

>100_bases
AATTTTTATCAAAATTGATGATTGAAGTATCATTTTAACTAATAATTGGTGTTAAATTTTATTGTATATTGTGTTTGTTT
ATATATGATATGGCGTTGTT

Product: protein kinase C1 inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQHSNDILDVNDELDGQLLGVCKKVALSLKKLD
FNICQGVNIYSAIGSEAGQVIFHTHFHVIPRFQGDNLGFKRNCSIELSGDEYLDLSKKISKNI

Sequences:

>Translated_143_residues
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQHSNDILDVNDELDGQLLGVCKKVALSLKKLD
FNICQGVNIYSAIGSEAGQVIFHTHFHVIPRFQGDNLGFKRNCSIELSGDEYLDLSKKISKNI
>Mature_143_residues
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQHSNDILDVNDELDGQLLGVCKKVALSLKKLD
FNICQGVNIYSAIGSEAGQVIFHTHFHVIPRFQGDNLGFKRNCSIELSGDEYLDLSKKISKNI

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=38.3177570093458, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=104, Percent_Identity=39.4230769230769, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 16084; Mature: 16084

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQHSNDILDVNDE
CHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCCC
LDGQLLGVCKKVALSLKKLDFNICQGVNIYSAIGSEAGQVIFHTHFHVIPRFQGDNLGFK
CCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCCCEEEEEEEEEEEEEECCCCCCEE
RNCSIELSGDEYLDLSKKISKNI
CCCEEEECCCCCCHHHHHHHCCC
>Mature Secondary Structure
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQHSNDILDVNDE
CHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCEEECCCC
LDGQLLGVCKKVALSLKKLDFNICQGVNIYSAIGSEAGQVIFHTHFHVIPRFQGDNLGFK
CCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHCCCCCEEEEEEEEEEEEEECCCCCCEE
RNCSIELSGDEYLDLSKKISKNI
CCCEEEECCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978084; 9403685 [H]