Click here to switch to the map view.

The map label for this gene is smc [H]

Identifier: 203283973

GI number: 203283973

Start: 53954

End: 56419

Strand: Reverse

Name: smc [H]

Synonym: BDU_49

Alternate gene names: 203283973

Gene position: 56419-53954 (Counterclockwise)

Preceding gene: 203283975

Following gene: 203283972

Centisome position: 6.06

GC content: 24.29

Gene sequence:

>2466_bases
GTGGGAGTAGTTTTGTTTTTAGAAAAAATAGGACTTTTAGGATTTAAGTCTTTTGTTAAAATGCAAGAATTAAAGTTAAA
TAGTAGTTTAAATTTTATAGTAGGTCCAAATGGTTGTGGAAAAAGTAATTTACTAGATGCAATTCGTTTTTGTATAGGTG
AAGATAATTTAAGTATTTTGAGAATTAAACATATAACAGATTTAATTTCTGTATCAAAATCTAAGGAATCTAATTTTGCT
GAGGTGACTCTTTTTTTTAATAATGAAGATCTCTCTATTGGTGATTTTAGAGATAAATTTTATATTAGAAGAAGGCTTTA
TAAAGATGGTACAAGTGAATATTTTTTAAATAATGATAATTTGAATCTTAAAAATTATATGGATCTTGTTAATAAGCTAA
GATTTAAGAATTCTCCTTATATGTTTATTAATCAGGGGAAGATTGAGAGAATATCTTCAAGTGGCAATATTAATTTAAAA
TCTCTAATAGAAGAGGCTAGTGGAATAGATATGCTTAGAGTTGAAGAGGAACAGGCATATAAGAGCTTAGAAAAATCTAG
AGAAAATTTGACTTCTCTTTTGATGTTGAGAGATGAATTAAATGAAAAATATGAAAAAATTAAGAATGACTTTTTGATTA
AAGATAAATACCAAAAATTAAAGAACGATTTAGAAGTATTGGATAAAAATTTAAGCTTGAAGAAGCTTTTTAATCTTAAC
TTTGAATTAACTAAACTTAAGAATGGCTTGAATATTAAAGATATAGACAATATTTTGCATTTAAGTAGTTTTTCTATTGA
AAGTATTAAGGAAAAATTAGAATTTTATTCTCTTAGAGAAAAGAATGTTATTAAGAATATTGAACTTATTAAAAAAGAAA
TTGAAATGTTAAAATCTAAGTTGCTTACAATGGAAATTAAGATTCAAAAATTAGAACATGATAAGAGGGGAAAATTAAAT
TTAGCAAATATTTTTATGGGCAATAAGTCACAGATTGAATCAGTAAAAGTAAGCATAAATGAAGAGCTTATGAATTTAAA
TAATTCCCTTCAAAGTAAAAAGAAAGATTTTTTCATATTGACTGATGAGATAAATAGGTATACCAGGAGTTTTTTTGAAC
TTGTTGATTTAGTATTGTCGATTGTCAAGGAAAGTAATATAGAAGAATTTGAGCAACTTAAAAAAAACATTTTAAATTCT
TTAAAATTGTTTGAAGATACATTAAGCATCAAATATCTTAAAAATATTAGAGAAAATTTACTTAAATATATAGTCAAGGA
AGATAAACTTTTAAATTTATTAAGAGAGAAAATTGAACCTATTTTTGAACAAAATGTTGATTTAAGAAAATTTTTGCTTA
CGAGAAATAATTCTAAGACTAGTCTTGCAAAGGAAATCACTACTATTGAGAGTTTAGTGTCTGAGAAGACATTAAAATTA
AATGAGATATTGGGTGAGATTGAATATACAGAGCTTTCTAGGCTTAAAAATGAAGATGAAATTAAATTAATTGATAGTAA
TTTAAAATTTTTATTTGAAACTAGGGATGAACTTAAGGAACGCCTTAATAATTTAAATTTAAAACTGGATGAATTAAACT
TGGAACGAAGTGACATTAATGTTAATTTAGACAAGTTTTTAAGTGATGCAAAAGGTAGTGAATTAGTTGGAAATAAAGAG
GTCAATACTTTGAGTGTATTAGATGCTTTTAAAAATTCATCTTATTATGAATACATGAAAAAGCAAGCAGAGTATGATAT
TTTATTGCATTCTAATTTGGATATTAAGGATGAGATAAAAGATTTTAATTTTGTTAATAAGGATATGGAAAAATTTGATC
TTGAAGATGATTTAGTACAGATAGCTTCTTTACGGAAAGAAATGAGTATGATTGAGCATGATAATTATATTTTTTTTAAT
GTTGAGAGGGAATATAATGAAATAAAGGATAAGGTTGAAAAAATAAATTTACAAATAAACGATTTAAATGCTACTAAAGA
ATCTTTAGATAAGCTTAGAAAAAGAATTAAGAGGGAAATTAATAAAAAATTTAATGATGCTTTCGATAAAATTAGTGATC
ATTTTATTTATTTTTTTAGTCGAATATTTAAGGGTAGTGGAAGTTTATTTTATGATAAGGATTTAGATGAAATAGAAATT
AAAATAAATTTTAAGGATAAATTAGTCAAAGGCAATAAAATGCTTTCTGGAGGAGAGCATTCTTTAATTAGTATAGCATT
TTTGTTTGCTTTGTATTATTATTCTCCTGCTTCATTTTGTGTACTTGATGAAATTGATGCTTCTCTTGATTTTGAAAATA
GTAATAAACTTTCAACACTTTTAAATGAACTTGGTCAAAAAGTTCAATTATTGATAATAACTCATAATATGTATGTTGCT
AAGGGAAGTAAGAATTTAATTGGTGTTACTAGTGATAATGGAGAAAGTGTAATATTTAATATATAA

Upstream 100 bases:

>100_bases
CAAAGATACACCCTCTTCCAACCTCATCAATTCCACAAATCATAACTATTTATTATAATACAGAATTATGTTTAGTAAAT
TAATATTGTTTATAATTTAA

Downstream 100 bases:

>100_bases
TTTATTTAGTATATTAGGAAAATTATTATGAGAGAGAAAAAGTTTCATTTTCAACAATATTTTTTAATATTAATATTTTT
ATTAATTATTGTTTCTTTTT

Product: P115 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MGVVLFLEKIGLLGFKSFVKMQELKLNSSLNFIVGPNGCGKSNLLDAIRFCIGEDNLSILRIKHITDLISVSKSKESNFA
EVTLFFNNEDLSIGDFRDKFYIRRRLYKDGTSEYFLNNDNLNLKNYMDLVNKLRFKNSPYMFINQGKIERISSSGNINLK
SLIEEASGIDMLRVEEEQAYKSLEKSRENLTSLLMLRDELNEKYEKIKNDFLIKDKYQKLKNDLEVLDKNLSLKKLFNLN
FELTKLKNGLNIKDIDNILHLSSFSIESIKEKLEFYSLREKNVIKNIELIKKEIEMLKSKLLTMEIKIQKLEHDKRGKLN
LANIFMGNKSQIESVKVSINEELMNLNNSLQSKKKDFFILTDEINRYTRSFFELVDLVLSIVKESNIEEFEQLKKNILNS
LKLFEDTLSIKYLKNIRENLLKYIVKEDKLLNLLREKIEPIFEQNVDLRKFLLTRNNSKTSLAKEITTIESLVSEKTLKL
NEILGEIEYTELSRLKNEDEIKLIDSNLKFLFETRDELKERLNNLNLKLDELNLERSDINVNLDKFLSDAKGSELVGNKE
VNTLSVLDAFKNSSYYEYMKKQAEYDILLHSNLDIKDEIKDFNFVNKDMEKFDLEDDLVQIASLRKEMSMIEHDNYIFFN
VEREYNEIKDKVEKINLQINDLNATKESLDKLRKRIKREINKKFNDAFDKISDHFIYFFSRIFKGSGSLFYDKDLDEIEI
KINFKDKLVKGNKMLSGGEHSLISIAFLFALYYYSPASFCVLDEIDASLDFENSNKLSTLLNELGQKVQLLIITHNMYVA
KGSKNLIGVTSDNGESVIFNI

Sequences:

>Translated_821_residues
MGVVLFLEKIGLLGFKSFVKMQELKLNSSLNFIVGPNGCGKSNLLDAIRFCIGEDNLSILRIKHITDLISVSKSKESNFA
EVTLFFNNEDLSIGDFRDKFYIRRRLYKDGTSEYFLNNDNLNLKNYMDLVNKLRFKNSPYMFINQGKIERISSSGNINLK
SLIEEASGIDMLRVEEEQAYKSLEKSRENLTSLLMLRDELNEKYEKIKNDFLIKDKYQKLKNDLEVLDKNLSLKKLFNLN
FELTKLKNGLNIKDIDNILHLSSFSIESIKEKLEFYSLREKNVIKNIELIKKEIEMLKSKLLTMEIKIQKLEHDKRGKLN
LANIFMGNKSQIESVKVSINEELMNLNNSLQSKKKDFFILTDEINRYTRSFFELVDLVLSIVKESNIEEFEQLKKNILNS
LKLFEDTLSIKYLKNIRENLLKYIVKEDKLLNLLREKIEPIFEQNVDLRKFLLTRNNSKTSLAKEITTIESLVSEKTLKL
NEILGEIEYTELSRLKNEDEIKLIDSNLKFLFETRDELKERLNNLNLKLDELNLERSDINVNLDKFLSDAKGSELVGNKE
VNTLSVLDAFKNSSYYEYMKKQAEYDILLHSNLDIKDEIKDFNFVNKDMEKFDLEDDLVQIASLRKEMSMIEHDNYIFFN
VEREYNEIKDKVEKINLQINDLNATKESLDKLRKRIKREINKKFNDAFDKISDHFIYFFSRIFKGSGSLFYDKDLDEIEI
KINFKDKLVKGNKMLSGGEHSLISIAFLFALYYYSPASFCVLDEIDASLDFENSNKLSTLLNELGQKVQLLIITHNMYVA
KGSKNLIGVTSDNGESVIFNI
>Mature_820_residues
GVVLFLEKIGLLGFKSFVKMQELKLNSSLNFIVGPNGCGKSNLLDAIRFCIGEDNLSILRIKHITDLISVSKSKESNFAE
VTLFFNNEDLSIGDFRDKFYIRRRLYKDGTSEYFLNNDNLNLKNYMDLVNKLRFKNSPYMFINQGKIERISSSGNINLKS
LIEEASGIDMLRVEEEQAYKSLEKSRENLTSLLMLRDELNEKYEKIKNDFLIKDKYQKLKNDLEVLDKNLSLKKLFNLNF
ELTKLKNGLNIKDIDNILHLSSFSIESIKEKLEFYSLREKNVIKNIELIKKEIEMLKSKLLTMEIKIQKLEHDKRGKLNL
ANIFMGNKSQIESVKVSINEELMNLNNSLQSKKKDFFILTDEINRYTRSFFELVDLVLSIVKESNIEEFEQLKKNILNSL
KLFEDTLSIKYLKNIRENLLKYIVKEDKLLNLLREKIEPIFEQNVDLRKFLLTRNNSKTSLAKEITTIESLVSEKTLKLN
EILGEIEYTELSRLKNEDEIKLIDSNLKFLFETRDELKERLNNLNLKLDELNLERSDINVNLDKFLSDAKGSELVGNKEV
NTLSVLDAFKNSSYYEYMKKQAEYDILLHSNLDIKDEIKDFNFVNKDMEKFDLEDDLVQIASLRKEMSMIEHDNYIFFNV
EREYNEIKDKVEKINLQINDLNATKESLDKLRKRIKREINKKFNDAFDKISDHFIYFFSRIFKGSGSLFYDKDLDEIEIK
INFKDKLVKGNKMLSGGEHSLISIAFLFALYYYSPASFCVLDEIDASLDFENSNKLSTLLNELGQKVQLLIITHNMYVAK
GSKNLIGVTSDNGESVIFNI

Specific function: Plays an important role in chromosome structure and partitioning. Essential for chromosome partition [H]

COG id: COG1196

COG function: function code D; Chromosome segregation ATPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family [H]

Homologues:

Organism=Homo sapiens, GI110347425, Length=232, Percent_Identity=29.7413793103448, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI110347420, Length=232, Percent_Identity=29.7413793103448, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI110347418, Length=232, Percent_Identity=29.7413793103448, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI30581135, Length=412, Percent_Identity=26.2135922330097, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4885399, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553272, Length=160, Percent_Identity=33.125, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17535279, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193202684, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321144, Length=356, Percent_Identity=28.0898876404494, Blast_Score=104, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321104, Length=180, Percent_Identity=27.2222222222222, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649535, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922276, Length=232, Percent_Identity=26.2931034482759, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395
- InterPro:   IPR010935
- InterPro:   IPR011890 [H]

Pfam domain/function: PF06470 SMC_hinge; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 95922; Mature: 95791

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVLFLEKIGLLGFKSFVKMQELKLNSSLNFIVGPNGCGKSNLLDAIRFCIGEDNLSIL
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
RIKHITDLISVSKSKESNFAEVTLFFNNEDLSIGDFRDKFYIRRRLYKDGTSEYFLNNDN
EHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
LNLKNYMDLVNKLRFKNSPYMFINQGKIERISSSGNINLKSLIEEASGIDMLRVEEEQAY
CCHHHHHHHHHHHHCCCCCEEEEECCCHHEECCCCCEEHHHHHHHHCCCCEEEECHHHHH
KSLEKSRENLTSLLMLRDELNEKYEKIKNDFLIKDKYQKLKNDLEVLDKNLSLKKLFNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCCHHHHHCCC
FELTKLKNGLNIKDIDNILHLSSFSIESIKEKLEFYSLREKNVIKNIELIKKEIEMLKSK
EEEEHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTMEIKIQKLEHDKRGKLNLANIFMGNKSQIESVKVSINEELMNLNNSLQSKKKDFFIL
HHHHEEEEEECCCCCCCCEEEEEEEECCCHHHHHEEEEHHHHHHHHHHHHHHCCCCEEEE
TDEINRYTRSFFELVDLVLSIVKESNIEEFEQLKKNILNSLKLFEDTLSIKYLKNIRENL
EHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKYIVKEDKLLNLLREKIEPIFEQNVDLRKFLLTRNNSKTSLAKEITTIESLVSEKTLKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NEILGEIEYTELSRLKNEDEIKLIDSNLKFLFETRDELKERLNNLNLKLDELNLERSDIN
HHHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
VNLDKFLSDAKGSELVGNKEVNTLSVLDAFKNSSYYEYMKKQAEYDILLHSNLDIKDEIK
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCHHHHHH
DFNFVNKDMEKFDLEDDLVQIASLRKEMSMIEHDNYIFFNVEREYNEIKDKVEKINLQIN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHEEEEE
DLNATKESLDKLRKRIKREINKKFNDAFDKISDHFIYFFSRIFKGSGSLFYDKDLDEIEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEE
KINFKDKLVKGNKMLSGGEHSLISIAFLFALYYYSPASFCVLDEIDASLDFENSNKLSTL
EEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
LNELGQKVQLLIITHNMYVAKGSKNLIGVTSDNGESVIFNI
HHHHCCCEEEEEEEECEEEECCCCCEEEEECCCCCEEEEEC
>Mature Secondary Structure 
GVVLFLEKIGLLGFKSFVKMQELKLNSSLNFIVGPNGCGKSNLLDAIRFCIGEDNLSIL
CCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
RIKHITDLISVSKSKESNFAEVTLFFNNEDLSIGDFRDKFYIRRRLYKDGTSEYFLNNDN
EHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
LNLKNYMDLVNKLRFKNSPYMFINQGKIERISSSGNINLKSLIEEASGIDMLRVEEEQAY
CCHHHHHHHHHHHHCCCCCEEEEECCCHHEECCCCCEEHHHHHHHHCCCCEEEECHHHHH
KSLEKSRENLTSLLMLRDELNEKYEKIKNDFLIKDKYQKLKNDLEVLDKNLSLKKLFNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHCCCCHHHHHCCC
FELTKLKNGLNIKDIDNILHLSSFSIESIKEKLEFYSLREKNVIKNIELIKKEIEMLKSK
EEEEHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTMEIKIQKLEHDKRGKLNLANIFMGNKSQIESVKVSINEELMNLNNSLQSKKKDFFIL
HHHHEEEEEECCCCCCCCEEEEEEEECCCHHHHHEEEEHHHHHHHHHHHHHHCCCCEEEE
TDEINRYTRSFFELVDLVLSIVKESNIEEFEQLKKNILNSLKLFEDTLSIKYLKNIRENL
EHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKYIVKEDKLLNLLREKIEPIFEQNVDLRKFLLTRNNSKTSLAKEITTIESLVSEKTLKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
NEILGEIEYTELSRLKNEDEIKLIDSNLKFLFETRDELKERLNNLNLKLDELNLERSDIN
HHHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
VNLDKFLSDAKGSELVGNKEVNTLSVLDAFKNSSYYEYMKKQAEYDILLHSNLDIKDEIK
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCHHHHHH
DFNFVNKDMEKFDLEDDLVQIASLRKEMSMIEHDNYIFFNVEREYNEIKDKVEKINLQIN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHEEEEE
DLNATKESLDKLRKRIKREINKKFNDAFDKISDHFIYFFSRIFKGSGSLFYDKDLDEIEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEE
KINFKDKLVKGNKMLSGGEHSLISIAFLFALYYYSPASFCVLDEIDASLDFENSNKLSTL
EEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
LNELGQKVQLLIITHNMYVAKGSKNLIGVTSDNGESVIFNI
HHHHCCCEEEEEEEECEEEECCCCCEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654983; 9384377; 7584053; 9701812; 9573042 [H]