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The map label for this gene is rpl7ae

Identifier: 20095034

GI number: 20095034

Start: 1607390

End: 1607761

Strand: Direct

Name: rpl7ae

Synonym: MK1598

Alternate gene names: 20095034

Gene position: 1607390-1607761 (Clockwise)

Preceding gene: 20095031

Following gene: 20095035

Centisome position: 94.83

GC content: 62.63

Gene sequence:

>372_bases
ATGTCCAAGCCCATGTACGTGAAGTTCGAGGTCCCGGAGGAGCTGGCCGAGAAGGCCTACGAGGCCCTCGAGATCGCTCG
GGACACCGGTCGTATCCGTAAGGGCACCAACGAGACCACCAAGGCCGTCGAGCGCGAGGAAGCCGTACTCGTGCTGATCG
CTGAAGACGTGGACCCCGAGGAAGTCGTCGCTCACCTACCGGAGCTCTGCGATGAGAAGGGCATTCCGTACGTGTACGTC
CCGAGCAAGGACGAGCTGGGTGCCGCCGCCGGCATCGACGTAGCCGCAGCCAGCGCGTGCATCATCGATCCCGGAGACGC
CAAGGACCTCGTGGACGAGATCATTGAGAAGGTCGAGGAGCTACGTGAGTAA

Upstream 100 bases:

>100_bases
GACACCGGCGAAACTTTATTTATTTCAACCGAGCGTCGGACGCCGGACGAGGAGATCGACCACGAGGATGAGGATGAACC
GATGAGTGGGGTGATGGTTA

Downstream 100 bases:

>100_bases
GCTGATCCTTTTCCCCGCAGCCCCTATCGTTACAGTTATCGTAACGAATTCTGTACTCAGTTAGGTGGCTCTCGCCGTTG
CGCCCGACGGTATCTTGGTA

Product: 50S ribosomal protein L7Ae

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MSKPMYVKFEVPEELAEKAYEALEIARDTGRIRKGTNETTKAVEREEAVLVLIAEDVDPEEVVAHLPELCDEKGIPYVYV
PSKDELGAAAGIDVAAASACIIDPGDAKDLVDEIIEKVEELRE

Sequences:

>Translated_123_residues
MSKPMYVKFEVPEELAEKAYEALEIARDTGRIRKGTNETTKAVEREEAVLVLIAEDVDPEEVVAHLPELCDEKGIPYVYV
PSKDELGAAAGIDVAAASACIIDPGDAKDLVDEIIEKVEELRE
>Mature_122_residues
SKPMYVKFEVPEELAEKAYEALEIARDTGRIRKGTNETTKAVEREEAVLVLIAEDVDPEEVVAHLPELCDEKGIPYVYVP
SKDELGAAAGIDVAAASACIIDPGDAKDLVDEIIEKVEELRE

Specific function: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs

COG id: COG1358

COG function: function code J; Ribosomal protein HS6-type (S12/L30/L7a)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L7Ae family

Homologues:

Organism=Homo sapiens, GI8923444, Length=107, Percent_Identity=35.5140186915888, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI4826860, Length=80, Percent_Identity=37.5, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI51317376, Length=80, Percent_Identity=37.5, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555988, Length=109, Percent_Identity=34.8623853211009, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32565833, Length=101, Percent_Identity=36.6336633663366, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565827, Length=98, Percent_Identity=36.734693877551, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320809, Length=124, Percent_Identity=33.8709677419355, Blast_Score=75, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319993, Length=108, Percent_Identity=34.2592592592593, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864298, Length=110, Percent_Identity=36.3636363636364, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356151, Length=123, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL7A_METKA (Q8TV03)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614881.1
- ProteinModelPortal:   Q8TV03
- SMR:   Q8TV03
- GeneID:   1478193
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1598
- NMPDR:   fig|190192.1.peg.1594
- HOGENOM:   HBG739027
- OMA:   GTNEATK
- ProtClustDB:   PRK04175
- BioCyc:   MKAN190192:MK1598-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_00326
- InterPro:   IPR004038
- InterPro:   IPR018492
- InterPro:   IPR022481
- InterPro:   IPR004037
- InterPro:   IPR000948
- PRINTS:   PR00881
- PRINTS:   PR00884
- TIGRFAMs:   TIGR03677

Pfam domain/function: PF01248 Ribosomal_L7Ae

EC number: NA

Molecular weight: Translated: 13485; Mature: 13354

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS01082 RIBOSOMAL_L7AE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPMYVKFEVPEELAEKAYEALEIARDTGRIRKGTNETTKAVEREEAVLVLIAEDVDPE
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCHH
EVVAHLPELCDEKGIPYVYVPSKDELGAAAGIDVAAASACIIDPGDAKDLVDEIIEKVEE
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHH
LRE
HCC
>Mature Secondary Structure 
SKPMYVKFEVPEELAEKAYEALEIARDTGRIRKGTNETTKAVEREEAVLVLIAEDVDPE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCHH
EVVAHLPELCDEKGIPYVYVPSKDELGAAAGIDVAAASACIIDPGDAKDLVDEIIEKVEE
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHH
LRE
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014