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The map label for this gene is hprK [H]

Identifier: 20094948

GI number: 20094948

Start: 1527145

End: 1527771

Strand: Direct

Name: hprK [H]

Synonym: MK1512

Alternate gene names: 20094948

Gene position: 1527145-1527771 (Clockwise)

Preceding gene: 20094947

Following gene: 20094949

Centisome position: 90.1

GC content: 60.45

Gene sequence:

>627_bases
GTGGAGCGGGTCGTCGTACATGGCACACTGATGGACGTGTTCGGGGTAGGGGTGCTTCTGGTAGGTCCACGTGGGGTAGG
GAAGAGCGAGACGGCCTTGGAACTCATACGTCGCGGCCACAGGTTGGTGTCCGACGATGCGGTGATCGTGGAGTGCGATG
ATAGCTACGAGTACCCCGTCGGCAGACCGCCGGAGAACTTAGCCGGGAAAATGGAGATCCGACTCGCCCTGGCGGAGCTG
TACTGCCCCGAGTGCGGTCGAGTGTACACATTCTCCGCCCTCAAGATGAAGGAAGGGTGTGACTGCGGTGGCGACCTGAA
ACTACGTCCTATTCAGGATAAAATCGCCGTGGACGTCGCGGAACTCTACGGCATCCGGGCGCTCCGGAGCCGTAAGGGCA
TCGGTGTGGTCATTAAGATGATCCCGGGCCCCCACCACCCCCATCACGATCCATCCATGAGACCGGATGAACCAGTCTCC
TCCACGCCTTCCGAGGAGGAGAAGGTAGTGAAATGGGTGAAAGAGAGGGATGGAAGGGTGTTCCACCTGGACGTGGTTCC
GGGTCGAGACACCGCCACGCTGATCGAGACCGTGGCACTTCAGGAGAGCTTGAGGCGCAGGAGGTGA

Upstream 100 bases:

>100_bases
CTCCACGGGGCTACCGGCGAGCGCTGGGAGGTGCACGAGACCAAGTGCATGGCCGAAGGTCACGACCACTGTGAGTTCGT
GGCGATACGGAGGGGGTAAC

Downstream 100 bases:

>100_bases
ACTGTGGTGCTGTCGATACCCGATTGGCTCGGTGCCGCACTGTTGCTTTCACTCAGTGACGAGCTGCACACCGGTCTCGT
GTGGGGAGCCCTTCGCAGCC

Product: serine protein kinase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MERVVVHGTLMDVFGVGVLLVGPRGVGKSETALELIRRGHRLVSDDAVIVECDDSYEYPVGRPPENLAGKMEIRLALAEL
YCPECGRVYTFSALKMKEGCDCGGDLKLRPIQDKIAVDVAELYGIRALRSRKGIGVVIKMIPGPHHPHHDPSMRPDEPVS
STPSEEEKVVKWVKERDGRVFHLDVVPGRDTATLIETVALQESLRRRR

Sequences:

>Translated_208_residues
MERVVVHGTLMDVFGVGVLLVGPRGVGKSETALELIRRGHRLVSDDAVIVECDDSYEYPVGRPPENLAGKMEIRLALAEL
YCPECGRVYTFSALKMKEGCDCGGDLKLRPIQDKIAVDVAELYGIRALRSRKGIGVVIKMIPGPHHPHHDPSMRPDEPVS
STPSEEEKVVKWVKERDGRVFHLDVVPGRDTATLIETVALQESLRRRR
>Mature_208_residues
MERVVVHGTLMDVFGVGVLLVGPRGVGKSETALELIRRGHRLVSDDAVIVECDDSYEYPVGRPPENLAGKMEIRLALAEL
YCPECGRVYTFSALKMKEGCDCGGDLKLRPIQDKIAVDVAELYGIRALRSRKGIGVVIKMIPGPHHPHHDPSMRPDEPVS
STPSEEEKVVKWVKERDGRVFHLDVVPGRDTATLIETVALQESLRRRR

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 23128; Mature: 23128

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVVVHGTLMDVFGVGVLLVGPRGVGKSETALELIRRGHRLVSDDAVIVECDDSYEYPV
CCEEEEEHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCEEECCCEEEEEECCCCCCCC
GRPPENLAGKMEIRLALAELYCPECGRVYTFSALKMKEGCDCGGDLKLRPIQDKIAVDVA
CCCCHHHCCHHHHEEEEHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHH
ELYGIRALRSRKGIGVVIKMIPGPHHPHHDPSMRPDEPVSSTPSEEEKVVKWVKERDGRV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
FHLDVVPGRDTATLIETVALQESLRRRR
EEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERVVVHGTLMDVFGVGVLLVGPRGVGKSETALELIRRGHRLVSDDAVIVECDDSYEYPV
CCEEEEEHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCEEECCCEEEEEECCCCCCCC
GRPPENLAGKMEIRLALAELYCPECGRVYTFSALKMKEGCDCGGDLKLRPIQDKIAVDVA
CCCCHHHCCHHHHEEEEHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHH
ELYGIRALRSRKGIGVVIKMIPGPHHPHHDPSMRPDEPVSSTPSEEEKVVKWVKERDGRV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
FHLDVVPGRDTATLIETVALQESLRRRR
EEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA