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The map label for this gene is CsdB [H]

Identifier: 20094873

GI number: 20094873

Start: 1467491

End: 1468675

Strand: Reverse

Name: CsdB [H]

Synonym: MK1437

Alternate gene names: 20094873

Gene position: 1468675-1467491 (Counterclockwise)

Preceding gene: 20094874

Following gene: 20094869

Centisome position: 86.65

GC content: 61.18

Gene sequence:

>1185_bases
TTGGGTTTGGATGAGATCGTGAACGGGTTTCCACTCAAGGAGGAGTGGGTGTACCTCGACAACGCCGCTACGTCGTTGAA
GCACGAACGCGTCATAAGCGCTATGGAGAGGGTCTTGCGGGAGTTCGGCGTGAACGTGGGTCGCGGGGCGCACCCTCCGG
GCGAGTGTGCCACAGAGGAGTTCGAGCGTGCTAGGGATATCGTCGCCTCGTTTCTCGGAGTCGAGCCGGAGTGCCTCGCC
TTCACGCTGAACACGACCCATTCGATCCACTACGTGCTGGCTTCGATCCGCTGGAAGAAAGGCGATGCCGTCGTCACCAC
GGCCCTCGAGCACCACTCGAACCTGGCACCGTGGTTGAGGTTCTCCGAGGTGTTGGGGTTCGAAGTCGAGGTGGTAGGGT
TCGACCGGGAGACCGGCGAGGTTGACATGGCTGAGTTGGAGTCCGTGGTCGACGACAACACACGTCTGATCGCCATAACT
CACGAGAGCAACGCCCTGGGTTCATTGCAGCCCGTGGACGAGATCTTAGAGCTCGCCGAGGAGGTCGGTGCGTACGTGCT
GCTCGACGCGGCCCAGTCGTTGGGCCACATGGATCACGATTGGTCGAGGTATCACTTCCTAGCGGCGCCCGGTCACAAGG
GCCTCTTAGGACCTCACGGTACCGGGATCCTTTACGTCCGCGAGGACGTGATGGAGGAACTGGAGCTACGGCTCCTCGGT
GGAGGGTCGACGGACTACGTAACCCGAGATCTCGAGGTCGTCCCCAGAGAACCCCCGCTCTCCTTCGAATCAGGAACACC
GAACCTTCCGGGTGTGATAGGGCTGGCGGAAGGTGTCAAGATCCTGGAGGAAGTCGGGTTGAACCGCGTGGAGCGGCGTA
TCCGCAAGGTCACCCGTCGGATCCTCAACGGGTTAGAGGAGCTGGAGGGAGTCGAGATTCTAGCACCCGAGGCGGAGAGG
AAGACCATCGTCCCGTTCCTGGTCGACGGCGTGGATTACGCGGAGGTGGGTAAAAAGCTCGGTGAGCGGAACATCTGCGT
GCGAACGGGGAGGCACTGTGCTAGCCTGGTGTTCGAGAGGCTAGGACTCGACGGTTGTGTTCGGGCCTCGGTGGCGTTCT
ACAACGACATCGAGGAAGCGGAGAGGTTCCTGGAGGTTGTAGAGGAGATAGCGCGCGGGTCGTGA

Upstream 100 bases:

>100_bases
TGCACGCCCGCTTAGGCGTCAAAGACGTCCGATAGCGTTAACGTTCCCGGCGGAGCAACGACTTTGAATCCATGATCAAA
GATCGGCCGGAGGGAAGGCG

Downstream 100 bases:

>100_bases
AGTTACCCTCGGAGCTTCCTCCTGATCCTCTCCCTCCTCGACCTACGCTCCTCCACGTACCGTTTGCCCGCGGCCCGGAT
TCGCTCGGCGAGCTTCGGTC

Product: selenocysteine lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MGLDEIVNGFPLKEEWVYLDNAATSLKHERVISAMERVLREFGVNVGRGAHPPGECATEEFERARDIVASFLGVEPECLA
FTLNTTHSIHYVLASIRWKKGDAVVTTALEHHSNLAPWLRFSEVLGFEVEVVGFDRETGEVDMAELESVVDDNTRLIAIT
HESNALGSLQPVDEILELAEEVGAYVLLDAAQSLGHMDHDWSRYHFLAAPGHKGLLGPHGTGILYVREDVMEELELRLLG
GGSTDYVTRDLEVVPREPPLSFESGTPNLPGVIGLAEGVKILEEVGLNRVERRIRKVTRRILNGLEELEGVEILAPEAER
KTIVPFLVDGVDYAEVGKKLGERNICVRTGRHCASLVFERLGLDGCVRASVAFYNDIEEAERFLEVVEEIARGS

Sequences:

>Translated_394_residues
MGLDEIVNGFPLKEEWVYLDNAATSLKHERVISAMERVLREFGVNVGRGAHPPGECATEEFERARDIVASFLGVEPECLA
FTLNTTHSIHYVLASIRWKKGDAVVTTALEHHSNLAPWLRFSEVLGFEVEVVGFDRETGEVDMAELESVVDDNTRLIAIT
HESNALGSLQPVDEILELAEEVGAYVLLDAAQSLGHMDHDWSRYHFLAAPGHKGLLGPHGTGILYVREDVMEELELRLLG
GGSTDYVTRDLEVVPREPPLSFESGTPNLPGVIGLAEGVKILEEVGLNRVERRIRKVTRRILNGLEELEGVEILAPEAER
KTIVPFLVDGVDYAEVGKKLGERNICVRTGRHCASLVFERLGLDGCVRASVAFYNDIEEAERFLEVVEEIARGS
>Mature_393_residues
GLDEIVNGFPLKEEWVYLDNAATSLKHERVISAMERVLREFGVNVGRGAHPPGECATEEFERARDIVASFLGVEPECLAF
TLNTTHSIHYVLASIRWKKGDAVVTTALEHHSNLAPWLRFSEVLGFEVEVVGFDRETGEVDMAELESVVDDNTRLIAITH
ESNALGSLQPVDEILELAEEVGAYVLLDAAQSLGHMDHDWSRYHFLAAPGHKGLLGPHGTGILYVREDVMEELELRLLGG
GSTDYVTRDLEVVPREPPLSFESGTPNLPGVIGLAEGVKILEEVGLNRVERRIRKVTRRILNGLEELEGVEILAPEAERK
TIVPFLVDGVDYAEVGKKLGERNICVRTGRHCASLVFERLGLDGCVRASVAFYNDIEEAERFLEVVEEIARGS

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=294, Percent_Identity=27.2108843537415, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787970, Length=394, Percent_Identity=33.502538071066, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789175, Length=387, Percent_Identity=30.2325581395349, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI48994898, Length=394, Percent_Identity=27.9187817258883, Blast_Score=115, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=304, Percent_Identity=28.9473684210526, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=346, Percent_Identity=21.0982658959538, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319831, Length=391, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI20129463, Length=244, Percent_Identity=32.7868852459016, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43627; Mature: 43496

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLDEIVNGFPLKEEWVYLDNAATSLKHERVISAMERVLREFGVNVGRGAHPPGECATEE
CCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FERARDIVASFLGVEPECLAFTLNTTHSIHYVLASIRWKKGDAVVTTALEHHSNLAPWLR
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHEECCCCEEEEHHHHHCCCCCHHHH
FSEVLGFEVEVVGFDRETGEVDMAELESVVDDNTRLIAITHESNALGSLQPVDEILELAE
HHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
EVGAYVLLDAAQSLGHMDHDWSRYHFLAAPGHKGLLGPHGTGILYVREDVMEELELRLLG
HHCCEEEEHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHEEEEC
GGSTDYVTRDLEVVPREPPLSFESGTPNLPGVIGLAEGVKILEEVGLNRVERRIRKVTRR
CCCCCCEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ILNGLEELEGVEILAPEAERKTIVPFLVDGVDYAEVGKKLGERNICVRTGRHCASLVFER
HHHHHHHHCCCEEECCCCCCCEECHHHCCCCCHHHHHHHHCCCCHHHHCCHHHHHHHHHH
LGLDGCVRASVAFYNDIEEAERFLEVVEEIARGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLDEIVNGFPLKEEWVYLDNAATSLKHERVISAMERVLREFGVNVGRGAHPPGECATEE
CHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FERARDIVASFLGVEPECLAFTLNTTHSIHYVLASIRWKKGDAVVTTALEHHSNLAPWLR
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHEECCCCEEEEHHHHHCCCCCHHHH
FSEVLGFEVEVVGFDRETGEVDMAELESVVDDNTRLIAITHESNALGSLQPVDEILELAE
HHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
EVGAYVLLDAAQSLGHMDHDWSRYHFLAAPGHKGLLGPHGTGILYVREDVMEELELRLLG
HHCCEEEEHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHEEEEC
GGSTDYVTRDLEVVPREPPLSFESGTPNLPGVIGLAEGVKILEEVGLNRVERRIRKVTRR
CCCCCCEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
ILNGLEELEGVEILAPEAERKTIVPFLVDGVDYAEVGKKLGERNICVRTGRHCASLVFER
HHHHHHHHCCCEEECCCCCCCEECHHHCCCCCHHHHHHHHCCCCHHHHCCHHHHHHHHHH
LGLDGCVRASVAFYNDIEEAERFLEVVEEIARGS
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]