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The map label for this gene is KptA

Identifier: 20094870

GI number: 20094870

Start: 1463176

End: 1463880

Strand: Direct

Name: KptA

Synonym: MK1434

Alternate gene names: 20094870

Gene position: 1463176-1463880 (Clockwise)

Preceding gene: 20094866

Following gene: 20094871

Centisome position: 86.32

GC content: 60.43

Gene sequence:

>705_bases
TTGAAACCTATCCGGGTATGCCCGGAGTGTGGCAAGTACACGGAAAAACATACCTGCGAGCGGTGTGGTCGGCGCACCGA
GGAGTTTTTGGACGGGCGGCGAAGGCTCGCGCTTAGCAAGCTCCTCTCGGGTATCCTCCGGCACTTCCCCGAAGAGGTGA
AGGTGAAACTCGACGACGAGGGTTTCACGGACTGCGACGTACACGAGCTGGCGGAGCGCATCAAGAAGTACTGGAAGAAC
CGCGAGTACTATCGTTGGCTCACTGGCGAGCACATCATCGCGGTTGTAGAGACCTGCCCCAAGGGCCGGTTCGAGATCGA
CGAACATGGCCGTATTCGGGCGAGGTACGGTCATTCGAGGCGTCTCAGTGTCAGGCCGACGCTCCCAGAAGCCGAGAACG
TCAAGGAACTGTACCACGGCACGGCACGTGAGAACCTGGAGTCTATACTCCAGCACGGAATCAAGCCGATGGGCAGACGG
GCGGTGCACCTGACGGACGACGAGCGTGAGGCCCTGATCACGGCGCTCCGTCACACTCGGAATCCGGTGATACTGGTCGT
CGACGCGGAACGGCTTCGACGGCATGGGTTGGTCCCCAGGAAAGCTGGCAAGAACGTCTACGTGGTGGAAGGAACGGTGC
CTCCGGACTGCATCACTCGCGTGATCCGGAACCCAAGGAGGTCCGTCGAGAGTGAAAAGCGCTGA

Upstream 100 bases:

>100_bases
CCTCCACGCGGATTACCCACGACACCGTCGGTTTCCCCCCACTTCGTCGCCAAGAGACACCTCAACATCTTATTAGGTTG
TCCGAACGAGGGGGAGGTCC

Downstream 100 bases:

>100_bases
ATGGTTCGAGGCCAGCACCGAGGAGGAGCGCGTAGAAATTCAGCGGAAGGTAGCCCGTAAGGTCCGACTGGAACCGCTCG
ACGACGTGGACGCCGTCGCT

Product: RNA:NAD 2'-phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKPIRVCPECGKYTEKHTCERCGRRTEEFLDGRRRLALSKLLSGILRHFPEEVKVKLDDEGFTDCDVHELAERIKKYWKN
REYYRWLTGEHIIAVVETCPKGRFEIDEHGRIRARYGHSRRLSVRPTLPEAENVKELYHGTARENLESILQHGIKPMGRR
AVHLTDDEREALITALRHTRNPVILVVDAERLRRHGLVPRKAGKNVYVVEGTVPPDCITRVIRNPRRSVESEKR

Sequences:

>Translated_234_residues
MKPIRVCPECGKYTEKHTCERCGRRTEEFLDGRRRLALSKLLSGILRHFPEEVKVKLDDEGFTDCDVHELAERIKKYWKN
REYYRWLTGEHIIAVVETCPKGRFEIDEHGRIRARYGHSRRLSVRPTLPEAENVKELYHGTARENLESILQHGIKPMGRR
AVHLTDDEREALITALRHTRNPVILVVDAERLRRHGLVPRKAGKNVYVVEGTVPPDCITRVIRNPRRSVESEKR
>Mature_234_residues
MKPIRVCPECGKYTEKHTCERCGRRTEEFLDGRRRLALSKLLSGILRHFPEEVKVKLDDEGFTDCDVHELAERIKKYWKN
REYYRWLTGEHIIAVVETCPKGRFEIDEHGRIRARYGHSRRLSVRPTLPEAENVKELYHGTARENLESILQHGIKPMGRR
AVHLTDDEREALITALRHTRNPVILVVDAERLRRHGLVPRKAGKNVYVVEGTVPPDCITRVIRNPRRSVESEKR

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family

Homologues:

Organism=Escherichia coli, GI87082424, Length=174, Percent_Identity=36.7816091954023, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KPTA_METKA (Q8X261)

Other databases:

- EMBL:   AF311944
- EMBL:   AE009439
- RefSeq:   NP_614717.1
- ProteinModelPortal:   Q8X261
- SMR:   Q8X261
- GeneID:   1478029
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1434
- NMPDR:   fig|190192.1.peg.1430
- HOGENOM:   HBG332834
- OMA:   TESRFLY
- BioCyc:   MKAN190192:MK1434-MONOMER
- HAMAP:   MF_00299
- InterPro:   IPR022928
- InterPro:   IPR002745

Pfam domain/function: PF01885 PTS_2-RNA

EC number: 2.7.-.- [C]

Molecular weight: Translated: 27357; Mature: 27357

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIRVCPECGKYTEKHTCERCGRRTEEFLDGRRRLALSKLLSGILRHFPEEVKVKLDDE
CCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCC
GFTDCDVHELAERIKKYWKNREYYRWLTGEHIIAVVETCPKGRFEIDEHGRIRARYGHSR
CCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCEECCCCCEEEECCCCC
RLSVRPTLPEAENVKELYHGTARENLESILQHGIKPMGRRAVHLTDDEREALITALRHTR
EEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCC
NPVILVVDAERLRRHGLVPRKAGKNVYVVEGTVPPDCITRVIRNPRRSVESEKR
CCEEEEECHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MKPIRVCPECGKYTEKHTCERCGRRTEEFLDGRRRLALSKLLSGILRHFPEEVKVKLDDE
CCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCC
GFTDCDVHELAERIKKYWKNREYYRWLTGEHIIAVVETCPKGRFEIDEHGRIRARYGHSR
CCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCEECCCCCEEEECCCCC
RLSVRPTLPEAENVKELYHGTARENLESILQHGIKPMGRRAVHLTDDEREALITALRHTR
EEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHCC
NPVILVVDAERLRRHGLVPRKAGKNVYVVEGTVPPDCITRVIRNPRRSVESEKR
CCEEEEECHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014