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The map label for this gene is mshA [H]

Identifier: 20094742

GI number: 20094742

Start: 1316132

End: 1317607

Strand: Reverse

Name: mshA [H]

Synonym: MK1306

Alternate gene names: 20094742

Gene position: 1317607-1316132 (Counterclockwise)

Preceding gene: 20094743

Following gene: 20094741

Centisome position: 77.74

GC content: 65.65

Gene sequence:

>1476_bases
ATGTTGGGTGGGCCCGAGGTCACCATCGTAACGGAGGGAACGTATCCCATCGCGCTCGGGGGAGTCACGACCTGGGTACA
GCGTCTCATCGAGCACTCCCCGAACGTCAGGTTCAACGTGCTCTGCCTGGCGCCCCCGGGGAAGACGGAGCCGGTCGTGG
ACATCCCGGAGAACGTCCGGGACGTGGTCGTCCGAGAGTTGGTACCGAGACGGATGGGGAAGCGCCGCTGGGCGGCCCGC
GTGTTCCCGGTTCACAGGATCCGGTGGCTGCTGGGACGCCGAGGTGAGTGGGCTCCCAGGGGTTTCCGCGTCCTGGAGCG
GGCCTTCGAGTATATACTGGAGGGCGAGCCGCTGGAGGAGGAGATGCTGAAACGGTTGTACGAGGTCTCGGAGAATCCTG
TGAAAGTACTGGAAGGACCGACGGTGTACACGCTGGCCCGGTACGTGGAGGACCAGCTGGGTTCGGACGAGCGGTTCAGC
GACCTGTACTGGGCGGTGTCGAACGTCTGCTCCTTCGTCATGGGGGCGGCATCGGGCGTCCGCCACATGCCCGAGTGCGA
CGTGGCTCACCCGCAGAACTGCGGCGTGTGTGGCTTCCTGTGCGCCATCAGGAAGGCCGTCAAAGGAACCCCGTACATCA
TCACGGAGCACGGCGTCTTGATCCGAGAGCTGGACACACGCCTCGAGGGACTCGGGGACGTAGCCCGGGAGCTGTACCGG
CGGTGCTTCGAGTCGATGATCGAGACCTCCTACCGGTACTGCGACGAGATCCTGGCGATCTCCGACTACCACCGGGAGCA
CGCCGTGAAGCAGGGTGCGCCGGAGGACCGCATCGACGTGATCTACTCGGGGATCGAGACCTGGAGGTTTCCACCGCCCT
CGGACGTGGAGAGGAAGTTCCGCGAGGCGGACAGACTCCACGTGGGGACGGTCGCCCGGGTCGAACCCATCAAGGGGATC
GACGTGTTCGTCCGGATGGCGGCGAGGGTCGCCAAGGAGATGGGACACGACAGGGTCCGGTTCCACGTGGTCGGACCCAT
CGATGACCGGGAGCACTACGAGAGGTGTCGGGAGATCGTAGAGCGGCGGGGGCTGGAGCGTGTCGTGAAGTTCCACGGAT
CCCAGTCTCCGGAGGAGATCCTGCGGTTCTACCACAAGTTCCACGTGTTCGTGCTCTCGAGCAGGTCCGAGGGGCTCCCC
ATGGCCCTCCTCGAGGCGATGAGCACCGGGTGTCCCGTGGTGGCGTCCGAGGTGGGCGCGGTCCCCTACATCGTCAAGGA
AGGGATAGGACGGACGTTCCCGGCGGAGGACCACGAGGCCGGTGCACGGGCCCTCCTGGAACTGCTCCAAGACCCGGAGG
CCCTCCTCCGGATGTCGTACACGGCAACGAGGGAGGCCCGGAGGTTCGACGTCACCAGGATGTGCGAGGAGTACACGCGT
CGATACGCGAAGTACGCGGTCCCCGACCCCGGGTGA

Upstream 100 bases:

>100_bases
AGTTCCGTCAATGCTCGAGTGAGTTAACGTTAGCTAATGTAACCCATATGGGAAATGTACATTATCGAGCTGTATTTTCA
GTAATGAATACCGGGTGATC

Downstream 100 bases:

>100_bases
GATCGAATGGGGTTCCTATCGGACGCCATCGACAAGGTCATCCGGGGCGTGAGGAGGGGAAGGGCGGACCTCAAGTCCGT
CGTCAGATCGGCGTTACTCT

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MLGGPEVTIVTEGTYPIALGGVTTWVQRLIEHSPNVRFNVLCLAPPGKTEPVVDIPENVRDVVVRELVPRRMGKRRWAAR
VFPVHRIRWLLGRRGEWAPRGFRVLERAFEYILEGEPLEEEMLKRLYEVSENPVKVLEGPTVYTLARYVEDQLGSDERFS
DLYWAVSNVCSFVMGAASGVRHMPECDVAHPQNCGVCGFLCAIRKAVKGTPYIITEHGVLIRELDTRLEGLGDVARELYR
RCFESMIETSYRYCDEILAISDYHREHAVKQGAPEDRIDVIYSGIETWRFPPPSDVERKFREADRLHVGTVARVEPIKGI
DVFVRMAARVAKEMGHDRVRFHVVGPIDDREHYERCREIVERRGLERVVKFHGSQSPEEILRFYHKFHVFVLSSRSEGLP
MALLEAMSTGCPVVASEVGAVPYIVKEGIGRTFPAEDHEAGARALLELLQDPEALLRMSYTATREARRFDVTRMCEEYTR
RYAKYAVPDPG

Sequences:

>Translated_491_residues
MLGGPEVTIVTEGTYPIALGGVTTWVQRLIEHSPNVRFNVLCLAPPGKTEPVVDIPENVRDVVVRELVPRRMGKRRWAAR
VFPVHRIRWLLGRRGEWAPRGFRVLERAFEYILEGEPLEEEMLKRLYEVSENPVKVLEGPTVYTLARYVEDQLGSDERFS
DLYWAVSNVCSFVMGAASGVRHMPECDVAHPQNCGVCGFLCAIRKAVKGTPYIITEHGVLIRELDTRLEGLGDVARELYR
RCFESMIETSYRYCDEILAISDYHREHAVKQGAPEDRIDVIYSGIETWRFPPPSDVERKFREADRLHVGTVARVEPIKGI
DVFVRMAARVAKEMGHDRVRFHVVGPIDDREHYERCREIVERRGLERVVKFHGSQSPEEILRFYHKFHVFVLSSRSEGLP
MALLEAMSTGCPVVASEVGAVPYIVKEGIGRTFPAEDHEAGARALLELLQDPEALLRMSYTATREARRFDVTRMCEEYTR
RYAKYAVPDPG
>Mature_491_residues
MLGGPEVTIVTEGTYPIALGGVTTWVQRLIEHSPNVRFNVLCLAPPGKTEPVVDIPENVRDVVVRELVPRRMGKRRWAAR
VFPVHRIRWLLGRRGEWAPRGFRVLERAFEYILEGEPLEEEMLKRLYEVSENPVKVLEGPTVYTLARYVEDQLGSDERFS
DLYWAVSNVCSFVMGAASGVRHMPECDVAHPQNCGVCGFLCAIRKAVKGTPYIITEHGVLIRELDTRLEGLGDVARELYR
RCFESMIETSYRYCDEILAISDYHREHAVKQGAPEDRIDVIYSGIETWRFPPPSDVERKFREADRLHVGTVARVEPIKGI
DVFVRMAARVAKEMGHDRVRFHVVGPIDDREHYERCREIVERRGLERVVKFHGSQSPEEILRFYHKFHVFVLSSRSEGLP
MALLEAMSTGCPVVASEVGAVPYIVKEGIGRTFPAEDHEAGARALLELLQDPEALLRMSYTATREARRFDVTRMCEEYTR
RYAKYAVPDPG

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=225, Percent_Identity=30.2222222222222, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 56097; Mature: 56097

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGGPEVTIVTEGTYPIALGGVTTWVQRLIEHSPNVRFNVLCLAPPGKTEPVVDIPENVR
CCCCCCEEEEECCCCCEEECHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHH
DVVVRELVPRRMGKRRWAARVFPVHRIRWLLGRRGEWAPRGFRVLERAFEYILEGEPLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
EMLKRLYEVSENPVKVLEGPTVYTLARYVEDQLGSDERFSDLYWAVSNVCSFVMGAASGV
HHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RHMPECDVAHPQNCGVCGFLCAIRKAVKGTPYIITEHGVLIRELDTRLEGLGDVARELYR
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RCFESMIETSYRYCDEILAISDYHREHAVKQGAPEDRIDVIYSGIETWRFPPPSDVERKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
READRLHVGTVARVEPIKGIDVFVRMAARVAKEMGHDRVRFHVVGPIDDREHYERCREIV
HHHCCEECCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
ERRGLERVVKFHGSQSPEEILRFYHKFHVFVLSSRSEGLPMALLEAMSTGCPVVASEVGA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCC
VPYIVKEGIGRTFPAEDHEAGARALLELLQDPEALLRMSYTATREARRFDVTRMCEEYTR
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYAKYAVPDPG
HHHHCCCCCCC
>Mature Secondary Structure
MLGGPEVTIVTEGTYPIALGGVTTWVQRLIEHSPNVRFNVLCLAPPGKTEPVVDIPENVR
CCCCCCEEEEECCCCCEEECHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHH
DVVVRELVPRRMGKRRWAARVFPVHRIRWLLGRRGEWAPRGFRVLERAFEYILEGEPLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
EMLKRLYEVSENPVKVLEGPTVYTLARYVEDQLGSDERFSDLYWAVSNVCSFVMGAASGV
HHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
RHMPECDVAHPQNCGVCGFLCAIRKAVKGTPYIITEHGVLIRELDTRLEGLGDVARELYR
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RCFESMIETSYRYCDEILAISDYHREHAVKQGAPEDRIDVIYSGIETWRFPPPSDVERKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
READRLHVGTVARVEPIKGIDVFVRMAARVAKEMGHDRVRFHVVGPIDDREHYERCREIV
HHHCCEECCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHH
ERRGLERVVKFHGSQSPEEILRFYHKFHVFVLSSRSEGLPMALLEAMSTGCPVVASEVGA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCHHHHHHCC
VPYIVKEGIGRTFPAEDHEAGARALLELLQDPEALLRMSYTATREARRFDVTRMCEEYTR
CHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYAKYAVPDPG
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA