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The map label for this gene is RplF

Identifier: 20094660

GI number: 20094660

Start: 1209774

End: 1210388

Strand: Direct

Name: RplF

Synonym: MK1224

Alternate gene names: 20094660

Gene position: 1209774-1210388 (Clockwise)

Preceding gene: 20094659

Following gene: 20094661

Centisome position: 71.37

GC content: 60.65

Gene sequence:

>615_bases
GTGGCGGAGGCCAAGTTCGAACCCGCGAAGGACGCCATTCCCGGCGTCATCGTGATGGAGGAACGCGTCAAGATCAAGGA
CGACGTCGAGATCGAGATCTCCCAGCGCGAGGACCGGCGGTACGAGGTCACCGTCAAGGGTCCGAAGGGCGAGGTCACGA
AGGAGTTCTACTACCCGGACGTGTACCTCTGGGTCGAGGACGACGAGGTCGTGATCGCCGCCACGAGGTCCAACCGGCGT
CAGAAGGCCATCCTAGGCATGATCAAGGCCTACATCGAGAACATGCAGAAGGGCGTCACCGAGGGCCACGAGTACAAGCT
CAAGCTGGTGTACTCGCACTTCCCGCCGGAGGTCAAGGTGGATCAGAAGGAGGGCAAGGTCTACATCGAGAACTTCATGG
GTGAGAACGTGCCGCGCGTCGCCGAGATCGTGGACCCGGAGAACACCGAGGTCATTGTGCAGGGCCAGGACATCATCGTG
CGTGGTATCGACAAGGAGGCTGTCGGACAGACCGCCGCGAACCTGGAGCAGGCCACGTACATCAAGGATCGGGACCCGCG
TGTGTTCCAGGACGGTATCTACATCGTCGAGAAGGACGGCAAGAAGATCGTGTAA

Upstream 100 bases:

>100_bases
ATCGTGACCACTCCCGAGGGCGTCATGAGCCACTACGAGGCGAAGGAGAGGGGCATCGGCGGACGGCTGCTCGCGTACGT
GTACTGAGGGGGACCGGACC

Downstream 100 bases:

>100_bases
GGGTGAGGTGCCTTGGTCCGGAACCCGAACCTCTCCAAGGAGGAGGAGCGCCTGCTCAAGCTCCGGGAGGAACTCAAGCG
GAAGAAGCCGAAGTTCCGCC

Product: ribosomal protein L6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MAEAKFEPAKDAIPGVIVMEERVKIKDDVEIEISQREDRRYEVTVKGPKGEVTKEFYYPDVYLWVEDDEVVIAATRSNRR
QKAILGMIKAYIENMQKGVTEGHEYKLKLVYSHFPPEVKVDQKEGKVYIENFMGENVPRVAEIVDPENTEVIVQGQDIIV
RGIDKEAVGQTAANLEQATYIKDRDPRVFQDGIYIVEKDGKKIV

Sequences:

>Translated_204_residues
MAEAKFEPAKDAIPGVIVMEERVKIKDDVEIEISQREDRRYEVTVKGPKGEVTKEFYYPDVYLWVEDDEVVIAATRSNRR
QKAILGMIKAYIENMQKGVTEGHEYKLKLVYSHFPPEVKVDQKEGKVYIENFMGENVPRVAEIVDPENTEVIVQGQDIIV
RGIDKEAVGQTAANLEQATYIKDRDPRVFQDGIYIVEKDGKKIV
>Mature_203_residues
AEAKFEPAKDAIPGVIVMEERVKIKDDVEIEISQREDRRYEVTVKGPKGEVTKEFYYPDVYLWVEDDEVVIAATRSNRRQ
KAILGMIKAYIENMQKGVTEGHEYKLKLVYSHFPPEVKVDQKEGKVYIENFMGENVPRVAEIVDPENTEVIVQGQDIIVR
GIDKEAVGQTAANLEQATYIKDRDPRVFQDGIYIVEKDGKKIV

Specific function: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center

COG id: COG0097

COG function: function code J; Ribosomal protein L6P/L9E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L6P family

Homologues:

Organism=Homo sapiens, GI15431303, Length=187, Percent_Identity=34.2245989304813, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI67944630, Length=187, Percent_Identity=34.2245989304813, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI310133141, Length=167, Percent_Identity=31.7365269461078, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI310118095, Length=122, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554746, Length=169, Percent_Identity=33.7278106508876, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324262, Length=186, Percent_Identity=33.8709677419355, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321291, Length=186, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583602, Length=179, Percent_Identity=32.4022346368715, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17137198, Length=179, Percent_Identity=32.4022346368715, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL6_METKA (Q8TW14)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614507.1
- HSSP:   P14135
- ProteinModelPortal:   Q8TW14
- SMR:   Q8TW14
- GeneID:   1477819
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1224
- NMPDR:   fig|190192.1.peg.1220
- HOGENOM:   HBG606796
- OMA:   CSHIENM
- BioCyc:   MKAN190192:MK1224-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01365_A
- InterPro:   IPR000702
- InterPro:   IPR020040
- InterPro:   IPR002359
- InterPro:   IPR019907
- Gene3D:   G3DSA:3.90.930.12
- PANTHER:   PTHR11655
- PIRSF:   PIRSF002162
- TIGRFAMs:   TIGR03653

Pfam domain/function: PF00347 Ribosomal_L6; SSF56053 Ribosomal_L6

EC number: NA

Molecular weight: Translated: 23378; Mature: 23247

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00700 RIBOSOMAL_L6_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAKFEPAKDAIPGVIVMEERVKIKDDVEIEISQREDRRYEVTVKGPKGEVTKEFYYPD
CCCCCCCCCHHCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCE
VYLWVEDDEVVIAATRSNRRQKAILGMIKAYIENMQKGVTEGHEYKLKLVYSHFPPEVKV
EEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEE
DQKEGKVYIENFMGENVPRVAEIVDPENTEVIVQGQDIIVRGIDKEAVGQTAANLEQATY
ECCCCEEEEEHHCCCCCCCHHHHCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHEE
IKDRDPRVFQDGIYIVEKDGKKIV
ECCCCCCEEECCEEEEECCCCCCC
>Mature Secondary Structure 
AEAKFEPAKDAIPGVIVMEERVKIKDDVEIEISQREDRRYEVTVKGPKGEVTKEFYYPD
CCCCCCCCHHCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCE
VYLWVEDDEVVIAATRSNRRQKAILGMIKAYIENMQKGVTEGHEYKLKLVYSHFPPEVKV
EEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEE
DQKEGKVYIENFMGENVPRVAEIVDPENTEVIVQGQDIIVRGIDKEAVGQTAANLEQATY
ECCCCEEEEEHHCCCCCCCHHHHCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHEE
IKDRDPRVFQDGIYIVEKDGKKIV
ECCCCCCEEECCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014