Click here to switch to the map view.

The map label for this gene is frhB [H]

Identifier: 20094365

GI number: 20094365

Start: 887505

End: 888422

Strand: Reverse

Name: frhB [H]

Synonym: MK0929

Alternate gene names: 20094365

Gene position: 888422-887505 (Counterclockwise)

Preceding gene: 20094366

Following gene: 20094361

Centisome position: 52.42

GC content: 60.24

Gene sequence:

>918_bases
ATGAGCAAGTTGGATGAGATCATGGTTAAGGGCGATCCAGAGCTGCTGGGAGACCACCTCGGCGTGTTCACGGCCCGCTC
GACCGAGCGCAAGGTCACGAAGGTCACCCAGGACGGAGGTATCGCCTCCGCCGTCATGATCTACGGCCTTGAAGAGGGAC
TGTTCGACGGCGTGATCGCCGCCGTCGCGGACCCGGACGACCCCGAGGAGCCTTGGAAGCCACGCCCAGTGGTCATCACC
GACCCGGACGAGGTCCTGGAGGCAGCCGGAACCAAGTACACGTACTGTCCCAACGTGAGCGTCCTCAAGGAGGCCGTGAG
GAGCTACGGTTGCGAGAAAGTAGCGATGGTCGGGACTCCGTGTCAGATCCGGGCCGTCCGTAAGGCACAGCTCTGCCCGA
TCGGGATGAGGCACGTTCCGGACAAGATCGAGCTACTGATAGGGATCATCTGCATGGAGAACTTCCCGTACGAGGGTATG
AAGACCATCATCGAGCAGCTCTGCGGCGTGTGGATACGTGAGGTCACCAAGATGGACATCGGTAACGGTAAGTTCTGGGT
GTACACGAAGGACGGCGAGGTGAAGTCGATCCCGATCGACGAAACGCACCCCTTCGAGGGTGAACCGTGCCACGTGTGCA
CGGATTACTGCGCCGAGCTCTCCGATCTAACCGCCGGCTCGGTGGGTTCACCGGACGGCTGGAGCACCGTGATCGTGCGG
ACGGAGAAGGCCAAGGAGATCCTCGACGACATGGTGGAGCAGGGTCTGCTGGAGGTTAAGAGCATCGAGGAGGTCAAGCC
AGGTCTCGGTCTCATTCAAAAGCTCGCCCAGGTGAAGAAGAACAAGAACCAGAAGGAGATCGAGGAGCGGAAGGAGCTCG
GCCTACCGGAACCGGGTAAAGTTCACGAATCCCTCTAA

Upstream 100 bases:

>100_bases
ACCGGTGCATCAAGTGTGGTGCGTGCTTCACGCAGTGCCCGAGGACGATCTGGCCGGGTGACGAGGCCATCAAGGAGCTA
ATCATGGGGGGTGAGTAACC

Downstream 100 bases:

>100_bases
AGCCGGTAGTATCGGAACCCCAGCTCCCTCGCCTTCTCCCACGCCTCTTCCAGTTCGTCCGCGGACGGTCGCCTGTTTAT
CTCCGGGTACTCGTACGCGC

Product: coenzyme F420-reducing hydrogenase subunit beta

Products: NA

Alternate protein names: 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit beta; FRH [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSKLDEIMVKGDPELLGDHLGVFTARSTERKVTKVTQDGGIASAVMIYGLEEGLFDGVIAAVADPDDPEEPWKPRPVVIT
DPDEVLEAAGTKYTYCPNVSVLKEAVRSYGCEKVAMVGTPCQIRAVRKAQLCPIGMRHVPDKIELLIGIICMENFPYEGM
KTIIEQLCGVWIREVTKMDIGNGKFWVYTKDGEVKSIPIDETHPFEGEPCHVCTDYCAELSDLTAGSVGSPDGWSTVIVR
TEKAKEILDDMVEQGLLEVKSIEEVKPGLGLIQKLAQVKKNKNQKEIEERKELGLPEPGKVHESL

Sequences:

>Translated_305_residues
MSKLDEIMVKGDPELLGDHLGVFTARSTERKVTKVTQDGGIASAVMIYGLEEGLFDGVIAAVADPDDPEEPWKPRPVVIT
DPDEVLEAAGTKYTYCPNVSVLKEAVRSYGCEKVAMVGTPCQIRAVRKAQLCPIGMRHVPDKIELLIGIICMENFPYEGM
KTIIEQLCGVWIREVTKMDIGNGKFWVYTKDGEVKSIPIDETHPFEGEPCHVCTDYCAELSDLTAGSVGSPDGWSTVIVR
TEKAKEILDDMVEQGLLEVKSIEEVKPGLGLIQKLAQVKKNKNQKEIEERKELGLPEPGKVHESL
>Mature_304_residues
SKLDEIMVKGDPELLGDHLGVFTARSTERKVTKVTQDGGIASAVMIYGLEEGLFDGVIAAVADPDDPEEPWKPRPVVITD
PDEVLEAAGTKYTYCPNVSVLKEAVRSYGCEKVAMVGTPCQIRAVRKAQLCPIGMRHVPDKIELLIGIICMENFPYEGMK
TIIEQLCGVWIREVTKMDIGNGKFWVYTKDGEVKSIPIDETHPFEGEPCHVCTDYCAELSDLTAGSVGSPDGWSTVIVRT
EKAKEILDDMVEQGLLEVKSIEEVKPGLGLIQKLAQVKKNKNQKEIEERKELGLPEPGKVHESL

Specific function: Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen [H]

COG id: COG1035

COG function: function code C; Coenzyme F420-reducing hydrogenase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frhB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007516
- InterPro:   IPR017679
- InterPro:   IPR007525 [H]

Pfam domain/function: PF04432 FrhB_FdhB_C; PF04422 FrhB_FdhB_N [H]

EC number: =1.12.98.1 [H]

Molecular weight: Translated: 33625; Mature: 33494

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLDEIMVKGDPELLGDHLGVFTARSTERKVTKVTQDGGIASAVMIYGLEEGLFDGVIA
CCCHHHHEECCCHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AVADPDDPEEPWKPRPVVITDPDEVLEAAGTKYTYCPNVSVLKEAVRSYGCEKVAMVGTP
HHCCCCCCCCCCCCCCEEEECHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCEEEEECCC
CQIRAVRKAQLCPIGMRHVPDKIELLIGIICMENFPYEGMKTIIEQLCGVWIREVTKMDI
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GNGKFWVYTKDGEVKSIPIDETHPFEGEPCHVCTDYCAELSDLTAGSVGSPDGWSTVIVR
CCCEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TEKAKEILDDMVEQGLLEVKSIEEVKPGLGLIQKLAQVKKNKNQKEIEERKELGLPEPGK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
VHESL
CCCCC
>Mature Secondary Structure 
SKLDEIMVKGDPELLGDHLGVFTARSTERKVTKVTQDGGIASAVMIYGLEEGLFDGVIA
CCHHHHEECCCHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AVADPDDPEEPWKPRPVVITDPDEVLEAAGTKYTYCPNVSVLKEAVRSYGCEKVAMVGTP
HHCCCCCCCCCCCCCCEEEECHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCEEEEECCC
CQIRAVRKAQLCPIGMRHVPDKIELLIGIICMENFPYEGMKTIIEQLCGVWIREVTKMDI
HHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GNGKFWVYTKDGEVKSIPIDETHPFEGEPCHVCTDYCAELSDLTAGSVGSPDGWSTVIVR
CCCEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TEKAKEILDDMVEQGLLEVKSIEEVKPGLGLIQKLAQVKKNKNQKEIEERKELGLPEPGK
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
VHESL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]