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The map label for this gene is MurC [H]

Identifier: 20094192

GI number: 20094192

Start: 716100

End: 717638

Strand: Reverse

Name: MurC [H]

Synonym: MK0755

Alternate gene names: 20094192

Gene position: 717638-716100 (Counterclockwise)

Preceding gene: 20094193

Following gene: 20094191

Centisome position: 42.34

GC content: 60.82

Gene sequence:

>1539_bases
TTGGCCGAACTTCCCTGGTCGACCGTTCTCGTGATCGGGGTCTGTGGGCCCGTATGCAATCTAGCGGCCCGGGTCCTCGC
GGAGCGCGGATACGATGTGATCGCGTCGGATCTCCGGGATGAGTGCGAGTTCGCCGAGACGCTTCTCGAATACAGTAACG
TGGAGCTCGTATTGGGAGGCCACCCACCCGAGATCTTCGAACGAGCCGAAGTTGTGGTACCTCCTCCGAGCCTATCACGC
GATGCTAAGCCGTACCGACTGGCCGAGGATCACGGCTGCGAAATCGTGGAAGTGAAGGAGCTCCTCGACATGTTACCGCC
CACACGACCGGTGATCGGAGTCGGTGGGACCAACGGGAAGACCACGACTGTGGCGATGATCAGGCACGTGTGCGAGCAAC
TCGGGCTCGAGGCCCCGCACCACGGTTTGCCGGGCATGCAAGGGAACGTCGGATTACTCCCCCCACTTCAGGCGCGTCTC
CCAGGGGACGTCAGCGTCTTAGAGATAGCAACTTTCGGGAAGAGAGGGGAGATCCTGGAAGCCGCGGAGTTATCCCAGGT
GGAGTGCGTCTGCGTTACCAACATCACCCCGGACCATCTGAACGAGGCGGGCGATTTCCTGACGTACGCCAGATGTGAGG
CCGAACTGTTGGAGCCGGACACCATCGAGCTAGCCGTGCTGAACGCTCAAGACCCGTTGGTAGTTGGTGCCCCCGAGGTG
GTGGATTTCAACGGCGATATCGTGTACTACGGGTTGGACGTGGAACCGTTCGATACCTCGGAAAAAGAGTGCTGGTGCGG
CGGACACGTTGAAGTCCATGAGATCCTCCCTTGGGTCGGTCCCTTCAAGTGCCGGGAGTGTGGCCTGCGATCTCCCGAGC
CGGACTACCTAGCTACGGACGTTGACTTGTCCGGGTTCCGACTGATCTGTCCCGATGGGGAGTACGAGGTTCGACTACCC
GTGATGGGGCTCCACAACGCTTACAACGCCCTCGCGGCGATAGCCGTCTGCTCCGAGTTCTTGGGACTTGATGTGGAGGA
CGTGGTAGAGGCGCTACAGTCCTTCGAAGGAGTCGAGGGCAGGTTAGAAGTACTCTGGGACGACGGCGAGCGAGTCGTGA
TCTTAGACTACGGCCATAATCCCGCCGGCGTGGACGCGACGTTGAGATGCGTGAAGGAGGCTTACCGGGAGCGGCGCGTC
TGCGCGGTAATCGCCGTAGCTTCGGAGCTGGGACCGGAAGGAGACGAAGAGATACTCAGAAGAGCTGCGGATCTCGCCGA
CCTAGTGGTGGTGGCATCGTACGCGGCGTACGAAGTCATGGACCGCGTCGACGCCGACAACGTGATCGCAGCGGAGAGCG
CCACCAAGCCGTTCGAGAAGAAGGGTACACTGGGTGCCTCTCGGGAGCAGGTGTTGGACGGTCTCAAGGAGGCGCTCCGC
TCGGACTGCGAAGTGGTAGTGTTGTTCGGAGAGGCTCCGCTGAAGTACCGGGAAGAGATCTCTGAAGAAGTCGAGCGAGT
GCTGGGGGACGAAAGGTGA

Upstream 100 bases:

>100_bases
TCGATACTGGCCGAGTACGGCCGAACGATACCGGGAGCGCGGCCGTGATCCCCGACAGGTTCAACTCACCGCGTCCCCAG
CCCCTCGGCGGGGTGCGCGG

Downstream 100 bases:

>100_bases
AGGTACTCTTCGTCGGCGCGAGGCTACTCCGGGACGTGGCGGAGTACGCCGGCTCCACGGGAGTGTACCGTATACTCACC
GAGTCGAACCCGAGGAGCAG

Product: UDP-N-acetylmuramate-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAELPWSTVLVIGVCGPVCNLAARVLAERGYDVIASDLRDECEFAETLLEYSNVELVLGGHPPEIFERAEVVVPPPSLSR
DAKPYRLAEDHGCEIVEVKELLDMLPPTRPVIGVGGTNGKTTTVAMIRHVCEQLGLEAPHHGLPGMQGNVGLLPPLQARL
PGDVSVLEIATFGKRGEILEAAELSQVECVCVTNITPDHLNEAGDFLTYARCEAELLEPDTIELAVLNAQDPLVVGAPEV
VDFNGDIVYYGLDVEPFDTSEKECWCGGHVEVHEILPWVGPFKCRECGLRSPEPDYLATDVDLSGFRLICPDGEYEVRLP
VMGLHNAYNALAAIAVCSEFLGLDVEDVVEALQSFEGVEGRLEVLWDDGERVVILDYGHNPAGVDATLRCVKEAYRERRV
CAVIAVASELGPEGDEEILRRAADLADLVVVASYAAYEVMDRVDADNVIAAESATKPFEKKGTLGASREQVLDGLKEALR
SDCEVVVLFGEAPLKYREEISEEVERVLGDER

Sequences:

>Translated_512_residues
MAELPWSTVLVIGVCGPVCNLAARVLAERGYDVIASDLRDECEFAETLLEYSNVELVLGGHPPEIFERAEVVVPPPSLSR
DAKPYRLAEDHGCEIVEVKELLDMLPPTRPVIGVGGTNGKTTTVAMIRHVCEQLGLEAPHHGLPGMQGNVGLLPPLQARL
PGDVSVLEIATFGKRGEILEAAELSQVECVCVTNITPDHLNEAGDFLTYARCEAELLEPDTIELAVLNAQDPLVVGAPEV
VDFNGDIVYYGLDVEPFDTSEKECWCGGHVEVHEILPWVGPFKCRECGLRSPEPDYLATDVDLSGFRLICPDGEYEVRLP
VMGLHNAYNALAAIAVCSEFLGLDVEDVVEALQSFEGVEGRLEVLWDDGERVVILDYGHNPAGVDATLRCVKEAYRERRV
CAVIAVASELGPEGDEEILRRAADLADLVVVASYAAYEVMDRVDADNVIAAESATKPFEKKGTLGASREQVLDGLKEALR
SDCEVVVLFGEAPLKYREEISEEVERVLGDER
>Mature_511_residues
AELPWSTVLVIGVCGPVCNLAARVLAERGYDVIASDLRDECEFAETLLEYSNVELVLGGHPPEIFERAEVVVPPPSLSRD
AKPYRLAEDHGCEIVEVKELLDMLPPTRPVIGVGGTNGKTTTVAMIRHVCEQLGLEAPHHGLPGMQGNVGLLPPLQARLP
GDVSVLEIATFGKRGEILEAAELSQVECVCVTNITPDHLNEAGDFLTYARCEAELLEPDTIELAVLNAQDPLVVGAPEVV
DFNGDIVYYGLDVEPFDTSEKECWCGGHVEVHEILPWVGPFKCRECGLRSPEPDYLATDVDLSGFRLICPDGEYEVRLPV
MGLHNAYNALAAIAVCSEFLGLDVEDVVEALQSFEGVEGRLEVLWDDGERVVILDYGHNPAGVDATLRCVKEAYRERRVC
AVIAVASELGPEGDEEILRRAADLADLVVVASYAAYEVMDRVDADNVIAAESATKPFEKKGTLGASREQVLDGLKEALRS
DCEVVVLFGEAPLKYREEISEEVERVLGDER

Specific function: Cell wall formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 55772; Mature: 55641

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELPWSTVLVIGVCGPVCNLAARVLAERGYDVIASDLRDECEFAETLLEYSNVELVLGG
CCCCCCHHEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
HPPEIFERAEVVVPPPSLSRDAKPYRLAEDHGCEIVEVKELLDMLPPTRPVIGVGGTNGK
CCHHHHCCCEEEECCCCCCCCCCCCEECCCCCCCEEEHHHHHHHCCCCCCEEEECCCCCC
TTTVAMIRHVCEQLGLEAPHHGLPGMQGNVGLLPPLQARLPGDVSVLEIATFGKRGEILE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEH
AAELSQVECVCVTNITPDHLNEAGDFLTYARCEAELLEPDTIELAVLNAQDPLVVGAPEV
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCE
VDFNGDIVYYGLDVEPFDTSEKECWCGGHVEVHEILPWVGPFKCRECGLRSPEPDYLATD
EECCCCEEEEECCCCCCCCCCCCEEECCCEEHHHHCCCCCCCHHHHCCCCCCCCCCEEEC
VDLSGFRLICPDGEYEVRLPVMGLHNAYNALAAIAVCSEFLGLDVEDVVEALQSFEGVEG
CCCCCEEEECCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
RLEVLWDDGERVVILDYGHNPAGVDATLRCVKEAYRERRVCAVIAVASELGPEGDEEILR
EEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHHEEEEHHHHCCCCHHHHHH
RAADLADLVVVASYAAYEVMDRVDADNVIAAESATKPFEKKGTLGASREQVLDGLKEALR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHH
SDCEVVVLFGEAPLKYREEISEEVERVLGDER
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AELPWSTVLVIGVCGPVCNLAARVLAERGYDVIASDLRDECEFAETLLEYSNVELVLGG
CCCCCHHEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
HPPEIFERAEVVVPPPSLSRDAKPYRLAEDHGCEIVEVKELLDMLPPTRPVIGVGGTNGK
CCHHHHCCCEEEECCCCCCCCCCCCEECCCCCCCEEEHHHHHHHCCCCCCEEEECCCCCC
TTTVAMIRHVCEQLGLEAPHHGLPGMQGNVGLLPPLQARLPGDVSVLEIATFGKRGEILE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEH
AAELSQVECVCVTNITPDHLNEAGDFLTYARCEAELLEPDTIELAVLNAQDPLVVGAPEV
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCE
VDFNGDIVYYGLDVEPFDTSEKECWCGGHVEVHEILPWVGPFKCRECGLRSPEPDYLATD
EECCCCEEEEECCCCCCCCCCCCEEECCCEEHHHHCCCCCCCHHHHCCCCCCCCCCEEEC
VDLSGFRLICPDGEYEVRLPVMGLHNAYNALAAIAVCSEFLGLDVEDVVEALQSFEGVEG
CCCCCEEEECCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
RLEVLWDDGERVVILDYGHNPAGVDATLRCVKEAYRERRVCAVIAVASELGPEGDEEILR
EEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHHEEEEHHHHCCCCHHHHHH
RAADLADLVVVASYAAYEVMDRVDADNVIAAESATKPFEKKGTLGASREQVLDGLKEALR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHH
SDCEVVVLFGEAPLKYREEISEEVERVLGDER
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA