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The map label for this gene is PyrF [H]

Identifier: 20094172

GI number: 20094172

Start: 700349

End: 701005

Strand: Reverse

Name: PyrF [H]

Synonym: MK0735

Alternate gene names: 20094172

Gene position: 701005-700349 (Counterclockwise)

Preceding gene: 20094173

Following gene: 20094153

Centisome position: 41.36

GC content: 63.47

Gene sequence:

>657_bases
GTGCTCGAACCCGATACGCGCCTGATCGTTGCGCTGGACGTGTCACCGGATCGCGCGGTGGAGATCGCGGAAACACTTGA
CGGATACGTCGACGGGTTCAAAGTAGGGTACGAAGTGGTGCTGGCCGAAGGGGCGGCGGGGATAGAGCGGGTCGCCGAAG
TGCTAGAAGAATCGTTCCTGCTCGTGGATTTGAAAACGGCGGACATTCCGGAGATATCGCGGTCGATCGTCGAGCGTGTG
AGCGAGGCCGGCGCCAACGCCGCCATAGTTCACGGGTTCGTAGGTCCGGACGTCGTCGAGGAATGCGCTGAGGTGCTACC
GGTGTTCGTGGTAGCTACGATGAGTCACCCGGGGGCGCGGGAGTTCTACGATCGAGCTTGCCGGGACATCGTTAAAGCAT
GCGACGACATCGACGGTGTTGTCGGGTACGTGGCCCCGGCGACGAGACCCGAGAGAGTCCGGGAGGTCCGGAAGATCACC
GACAAGCTCATCGCCAGCCCCGGTGTAGGAGCTCAGGGAGCGGCGCCCGGTGACGCGGTGCGAGCTGGTGCGGATTTCGA
GATAGTCGGTCGGGCGATCACGGAAGCGCACGACCCCGTGGAAGCGGCGAAGGATTTGACTCGGGCGATGAGGACTTCCA
GGCCGGCCGAACGGTGA

Upstream 100 bases:

>100_bases
TGGGCTGGGCATTTGGGGTCCTGGACGGTATCACGGCACTCGCCGTCATAACCTTCGACCTCGGGTACCACGCTGCGGAA
CTGTTGACGGGGGCGATCAG

Downstream 100 bases:

>100_bases
CGAGTCCCATGAGCGCCGAGCCCCACTCATGACCGTTATGGTGTCCATAACGATCCTCGGTGCCCGGGGTCGGGACCTGA
ACTGGGGGTCAGCGCTCGAG

Product: orotidine-5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLEPDTRLIVALDVSPDRAVEIAETLDGYVDGFKVGYEVVLAEGAAGIERVAEVLEESFLLVDLKTADIPEISRSIVERV
SEAGANAAIVHGFVGPDVVEECAEVLPVFVVATMSHPGAREFYDRACRDIVKACDDIDGVVGYVAPATRPERVREVRKIT
DKLIASPGVGAQGAAPGDAVRAGADFEIVGRAITEAHDPVEAAKDLTRAMRTSRPAER

Sequences:

>Translated_218_residues
MLEPDTRLIVALDVSPDRAVEIAETLDGYVDGFKVGYEVVLAEGAAGIERVAEVLEESFLLVDLKTADIPEISRSIVERV
SEAGANAAIVHGFVGPDVVEECAEVLPVFVVATMSHPGAREFYDRACRDIVKACDDIDGVVGYVAPATRPERVREVRKIT
DKLIASPGVGAQGAAPGDAVRAGADFEIVGRAITEAHDPVEAAKDLTRAMRTSRPAER
>Mature_218_residues
MLEPDTRLIVALDVSPDRAVEIAETLDGYVDGFKVGYEVVLAEGAAGIERVAEVLEESFLLVDLKTADIPEISRSIVERV
SEAGANAAIVHGFVGPDVVEECAEVLPVFVVATMSHPGAREFYDRACRDIVKACDDIDGVVGYVAPATRPERVREVRKIT
DKLIASPGVGAQGAAPGDAVRAGADFEIVGRAITEAHDPVEAAKDLTRAMRTSRPAER

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23223; Mature: 23223

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEPDTRLIVALDVSPDRAVEIAETLDGYVDGFKVGYEVVLAEGAAGIERVAEVLEESFL
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHE
LVDLKTADIPEISRSIVERVSEAGANAAIVHGFVGPDVVEECAEVLPVFVVATMSHPGAR
EEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHH
EFYDRACRDIVKACDDIDGVVGYVAPATRPERVREVRKITDKLIASPGVGAQGAAPGDAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RAGADFEIVGRAITEAHDPVEAAKDLTRAMRTSRPAER
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLEPDTRLIVALDVSPDRAVEIAETLDGYVDGFKVGYEVVLAEGAAGIERVAEVLEESFL
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHE
LVDLKTADIPEISRSIVERVSEAGANAAIVHGFVGPDVVEECAEVLPVFVVATMSHPGAR
EEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHH
EFYDRACRDIVKACDDIDGVVGYVAPATRPERVREVRKITDKLIASPGVGAQGAAPGDAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RAGADFEIVGRAITEAHDPVEAAKDLTRAMRTSRPAER
HCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA