Click here to switch to the map view.

The map label for this gene is moaC

Identifier: 20093992

GI number: 20093992

Start: 516136

End: 516606

Strand: Reverse

Name: moaC

Synonym: MK0554

Alternate gene names: 20093992

Gene position: 516606-516136 (Counterclockwise)

Preceding gene: 20093994

Following gene: 20093983

Centisome position: 30.48

GC content: 56.48

Gene sequence:

>471_bases
GTGACCGCTGGGGGAAGACGGATGTCGATGGTTGACGTCACCGGGAAGAAAGAGGAGATCCGCATTGCCGAAGCTAGCGG
GTTCCTCAGGCTGACCGAGGACGGTGTGAACGCGGTGAAATCGGGTGAATCTCACCCACAGGGTAAGGGCGATCCTATCG
AGGTTGCCAAGGTAGCCGCCATACTCGCCGTGAAGAAGACGCCGGAGTTAGTTCCCCACTGTCATCCTATCAAGATCACT
GGCGTCGATGTCGACGTCGAGGTCCTCGAGGACGGCGTGAAGATGTCGGTACGAGTTAAGTCCGAGGGGAAGACGGGTGT
CGAAATGGACGCTCTCACCGGGTTAGTGGTCGGATTAGTCACGCTCTGGGACATGGTTAAGTACGCTGAGAAGGACGAAG
AGGGGCAGTACCCACACACCCGCATCGAGAACGTTAGGGTGGTGGAGAAAATCATCAAAGAGAAGGAGTAA

Upstream 100 bases:

>100_bases
CGCCTTTCCTCATATTGTTATGGATTTCGTAACAATACGCGAGGTGGGATGAACGGGTCCCGCAGTACCGACCACTTGTG
GGTGATGAGCCCCTTTAGGA

Downstream 100 bases:

>100_bases
GTTCCCCCTAAACGTCGCCGCGGCTATGAACGACAACATGCGGTAACACCTCGATGAGGAGTTCCGCTCCTAACTTCACC
GCGTTCGGCGACCCCGGTAG

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTAGGRRMSMVDVTGKKEEIRIAEASGFLRLTEDGVNAVKSGESHPQGKGDPIEVAKVAAILAVKKTPELVPHCHPIKIT
GVDVDVEVLEDGVKMSVRVKSEGKTGVEMDALTGLVVGLVTLWDMVKYAEKDEEGQYPHTRIENVRVVEKIIKEKE

Sequences:

>Translated_156_residues
MTAGGRRMSMVDVTGKKEEIRIAEASGFLRLTEDGVNAVKSGESHPQGKGDPIEVAKVAAILAVKKTPELVPHCHPIKIT
GVDVDVEVLEDGVKMSVRVKSEGKTGVEMDALTGLVVGLVTLWDMVKYAEKDEEGQYPHTRIENVRVVEKIIKEKE
>Mature_155_residues
TAGGRRMSMVDVTGKKEEIRIAEASGFLRLTEDGVNAVKSGESHPQGKGDPIEVAKVAAILAVKKTPELVPHCHPIKITG
VDVDVEVLEDGVKMSVRVKSEGKTGVEMDALTGLVVGLVTLWDMVKYAEKDEEGQYPHTRIENVRVVEKIIKEKE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=125, Percent_Identity=36.8, Blast_Score=87, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32566331, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574492, Length=143, Percent_Identity=34.965034965035, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574490, Length=149, Percent_Identity=34.2281879194631, Blast_Score=83, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_METKA (Q8TXV5)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613839.1
- ProteinModelPortal:   Q8TXV5
- SMR:   Q8TXV5
- GeneID:   1476655
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0554
- NMPDR:   fig|190192.1.peg.552
- HOGENOM:   HBG605231
- OMA:   VEETHEV
- ProtClustDB:   PRK12343
- BioCyc:   MKAN190192:MK0554-MONOMER
- HAMAP:   MF_01224_A
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17004; Mature: 16873

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: ACT_SITE 124-124

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGGRRMSMVDVTGKKEEIRIAEASGFLRLTEDGVNAVKSGESHPQGKGDPIEVAKVAA
CCCCCCEEEEEECCCCCCEEEEECCCCEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHH
ILAVKKTPELVPHCHPIKITGVDVDVEVLEDGVKMSVRVKSEGKTGVEMDALTGLVVGLV
HHHHCCCCCCCCCCCCEEEECCCCCHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
TLWDMVKYAEKDEEGQYPHTRIENVRVVEKIIKEKE
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAGGRRMSMVDVTGKKEEIRIAEASGFLRLTEDGVNAVKSGESHPQGKGDPIEVAKVAA
CCCCCEEEEEECCCCCCEEEEECCCCEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHH
ILAVKKTPELVPHCHPIKITGVDVDVEVLEDGVKMSVRVKSEGKTGVEMDALTGLVVGLV
HHHHCCCCCCCCCCCCEEEECCCCCHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
TLWDMVKYAEKDEEGQYPHTRIENVRVVEKIIKEKE
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014