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The map label for this gene is TFA1 [H]

Identifier: 20093933

GI number: 20093933

Start: 456001

End: 456582

Strand: Reverse

Name: TFA1 [H]

Synonym: MK0495

Alternate gene names: 20093933

Gene position: 456582-456001 (Counterclockwise)

Preceding gene: 20093934

Following gene: 20093932

Centisome position: 26.94

GC content: 55.84

Gene sequence:

>582_bases
GTGGGGGGTTCAAACGTGTATGCCGAGCTGGGTGAGGAAGATCTGGAGGTCCTCAGAGACGTAACTTTATCGCTCCTAGA
CAGTGAGAAAGGAGTGGACCCTGAAGTCGCTAAGAGAACCGTGGATGTGATACTCAAGCGTGAGGCTATCGACGAAGAGA
TAGCCGAGGAGTTGGGTGTTGACCCGAGAGAAGTGCGGAAGGTGCTCTACAAGCTCCATGAACGTGGCGTTGTGACGTTC
AGAAAGGAGCGTCGAGAAGAGTACCGGTACCCCGTTTACTCCTGGCGGCTCAACCTACGAGAAGTCCTCAGGAGGTGCCT
CGAGGAGCGTCGACGGGAGCTCGAAGAGGTCGAGCGTGCACTCAGTAATGACATGTCTCATCCTATGTTTCACTGTGGGA
ACGATGACTGCCCTAGAATGTCGTTCGAGGAGGCTATGGAACACGAGTTCCGATGCCCTAAGTGCGGTGAAGTGCTGGAA
GAGGTGGATCTCACCGAGGAGCGGCGCGAGCTGGAACGGCTAGCGGAGGAACTAAAAGTGGAGATCCGAAGGCTGGAGGA
GCTCAGGGAACGGCTCGGTTGA

Upstream 100 bases:

>100_bases
GCTGAGGGTGAGTGTTCAGCTGTTATAGTCCATCCGCGTAAGGACACGTTCCGTCGATTACACAAATTTATTACATGCTT
GAAGCGCATCCAGTAAGGGG

Downstream 100 bases:

>100_bases
GGGACCCCATTAGGGATTTAGAGCGAGTAGGTTGCCCCGAGCACGTTATCGAGCACTGCAAGGCCGTCTGTCGCTTGGCT
GAAGAGATGGCCGAAAGATG

Product: transcription initiation factor IIE, large subunit

Products: NA

Alternate protein names: TFE; TFIIE subunit alpha homolog; Transcription initiation factor TFIIE [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MGGSNVYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGVDPREVRKVLYKLHERGVVTF
RKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERALSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLE
EVDLTEERRELERLAEELKVEIRRLEELRERLG

Sequences:

>Translated_193_residues
MGGSNVYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGVDPREVRKVLYKLHERGVVTF
RKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERALSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLE
EVDLTEERRELERLAEELKVEIRRLEELRERLG
>Mature_192_residues
GGSNVYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGVDPREVRKVLYKLHERGVVTFR
KERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERALSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLEE
VDLTEERRELERLAEELKVEIRRLEELRERLG

Specific function: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (tbp), and transcription factor B (tfb) and RNA po

COG id: COG1675

COG function: function code K; Transcription initiation factor IIE, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH TFE/IIEalpha-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016481
- InterPro:   IPR017919
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23019; Mature: 22888

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGSNVYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGV
CCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPREVRKVLYKLHERGVVTFRKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLEEVDLTEERRELERLAEELKV
HHCCCCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIRRLEELRERLG
HHHHHHHHHHHCC
>Mature Secondary Structure 
GGSNVYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGV
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPREVRKVLYKLHERGVVTFRKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLEEVDLTEERRELERLAEELKV
HHCCCCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIRRLEELRERLG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]