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The map label for this gene is rpl4lp

Identifier: 20093852

GI number: 20093852

Start: 391593

End: 392375

Strand: Reverse

Name: rpl4lp

Synonym: MK0414

Alternate gene names: 20093852

Gene position: 392375-391593 (Counterclockwise)

Preceding gene: 20093853

Following gene: 20093851

Centisome position: 23.15

GC content: 64.88

Gene sequence:

>783_bases
GTGGAGGCTCCCGTTTTCAACCTCGAGGGTGAAGAGGTCGACACGGTCGAGCTACCGTCTTTCTTCGAGGAGCCGGTCCG
TAAGGACCTCATCCGGCGCGCGGTGCTGGCAGCTCAGGCTAACCGCCGCCAACCCTACGGTACCGACCCGCGCGCAGGTT
TCAGGACGAGCGCCGAGTCCTGGGGTGCCGGTCACGGCGTGGCGATGGTCCCGAGGGTCAAGGGACGGAGGCACCCGGCG
GCCGGTAGGGCTGCCAGGGTCGCCCAAGCGGTCGGAGGACAGAAGGCCCACGCACCGACACCCGAGAAGGACTGGACCCA
GCGGGTTAACAGGAAGGAGCGACGTGCAGCGCTCAGATCCGCTCTGGCGGCGACAGCCAAGCCCGAGTTCGTGAAGGAGC
GCGGCCATGTGATCGACGATGTTCCACACCTCCCGGTGGTGGTCGTGGACGAGCTGAAAAGCCTGAACAAGGCTCGGGAG
GTCCGGGAATTCTTCAAGAGCGTCGGGTTGTGGGCCGACGTAGAGCGGGCCAAGAGCAATCGACGCATCCGGGCAGGTAA
GGGTAAGCGGCGCGGTCGACGGTACGTAAAGCCGAAGAGCGTGCTCATCGTGGTGGACGAGGACGAGGGTATCAAGTTAG
GTGCTAGAAACCATCCAGGTGTCGACGTGGTCGAGGCGATGCACCTGGGCGTCGAACACCTGGCTCCCGGTGCGCATCCC
GGGCGACTGACTGTGTTCACACCCGGAGCCCTGGAGGTACTGGAAGAGCGTCTGGGGGAGTAA

Upstream 100 bases:

>100_bases
TCAGTCGGACGTCGCAGCAGGGTGTCCGGCCGAAGGCCTCCGAGGATGAGATCGTGGAGCAGCTCGGAGGTCCCGCGAGT
GCCTAAGGGGGTAGTAGATA

Downstream 100 bases:

>100_bases
ACCGTGGCCAAGAGATACGGTCCTAAGATCGAAGACCCACACGACGTCCTACTGTACCCAGTGGCCACTGAGAAGGCGAT
GCGGTTGATGGAGGCGGAGA

Product: 50S ribosomal protein L4P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAESWGAGHGVAMVPRVKGRRHPA
AGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRSALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKARE
VREFFKSVGLWADVERAKSNRRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHP
GRLTVFTPGALEVLEERLGE

Sequences:

>Translated_260_residues
MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAESWGAGHGVAMVPRVKGRRHPA
AGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRSALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKARE
VREFFKSVGLWADVERAKSNRRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHP
GRLTVFTPGALEVLEERLGE
>Mature_260_residues
MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAESWGAGHGVAMVPRVKGRRHPA
AGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRSALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKARE
VREFFKSVGLWADVERAKSNRRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHP
GRLTVFTPGALEVLEERLGE

Specific function: Forms part of the polypeptide exit tunnel

COG id: COG0088

COG function: function code J; Ribosomal protein L4

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L4P family

Homologues:

Organism=Homo sapiens, GI16579885, Length=257, Percent_Identity=38.5214007782101, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17508669, Length=244, Percent_Identity=36.8852459016393, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6320215, Length=261, Percent_Identity=37.5478927203065, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319505, Length=261, Percent_Identity=37.5478927203065, Blast_Score=153, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24650747, Length=246, Percent_Identity=37.3983739837398, Blast_Score=167, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL4_METKA (Q8TY91)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613699.1
- ProteinModelPortal:   Q8TY91
- SMR:   Q8TY91
- GeneID:   1477717
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0414
- NMPDR:   fig|190192.1.peg.412
- HOGENOM:   HBG316531
- OMA:   KMRGRRY
- ProtClustDB:   PRK04042
- BioCyc:   MKAN190192:MK0414-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01328_A
- InterPro:   IPR002136
- InterPro:   IPR013000
- InterPro:   IPR019970
- TIGRFAMs:   TIGR03672

Pfam domain/function: PF00573 Ribosomal_L4; SSF52166 Ribosomal_L4/L1E

EC number: NA

Molecular weight: Translated: 28710; Mature: 28710

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: PS00939 RIBOSOMAL_L1E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAES
CCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
WGAGHGVAMVPRVKGRRHPAAGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRS
CCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKAREVREFFKSVGLWADVERAKSN
HHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
RRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHP
CCEECCCCHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCC
GRLTVFTPGALEVLEERLGE
CEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MEAPVFNLEGEEVDTVELPSFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTSAES
CCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
WGAGHGVAMVPRVKGRRHPAAGRAARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRS
CCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALAATAKPEFVKERGHVIDDVPHLPVVVVDELKSLNKAREVREFFKSVGLWADVERAKSN
HHHHHCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
RRIRAGKGKRRGRRYVKPKSVLIVVDEDEGIKLGARNHPGVDVVEAMHLGVEHLAPGAHP
CCEECCCCHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCC
GRLTVFTPGALEVLEERLGE
CEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014