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The map label for this gene is EFB1

Identifier: 20093695

GI number: 20093695

Start: 246012

End: 246296

Strand: Reverse

Name: EFB1

Synonym: MK0255

Alternate gene names: 20093695

Gene position: 246296-246012 (Counterclockwise)

Preceding gene: 20093696

Following gene: 20093694

Centisome position: 14.53

GC content: 59.65

Gene sequence:

>285_bases
GTGATAGTGGTGTCGAAAGTACTCGTGGACCTGAAAGTCCTCCCGGAGAGTGCCGATGTGGACTACGAGGAACTCAAGGA
GGCCATCCGCGAGAAGCTCGAGTCCATGGACGTCGTGGACATCGAAGGCATGGAGGAAGAACCTATCGCCTTCGGGCTGA
AGGCGATCAGAGTGAAGGTGGTAGTGCCGGACGCCGAGGGAGGTACCGACGCGCTCGAGGACGCTCTCAAGGAGGTCGAC
GAGGTCAATCAGGTCGAGGTGGTGAGTGCCAGTCGCACCCTCTGA

Upstream 100 bases:

>100_bases
CCGAAGTGCGGTGAGGTCGTGATCACCCGATGCCAGAAGTGTAGGAGGTTGGGCAACCGGTACCAGTGTCCCAACTGCGG
CTTCATAGGTCCTTAAGGGG

Downstream 100 bases:

>100_bases
GCGCCCCGTGGGGAAACGTTATTGGAGTCGAAACATTTGCGCTTTCTACGTGTCCTGGAGGAGGTGGTTTCCGATCTCCC
CGAACGCGTCCTTCGGCGAC

Product: translation elongation factor EF-1beta

Products: NA

Alternate protein names: EF-1-beta; aEF-1beta

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MIVVSKVLVDLKVLPESADVDYEELKEAIREKLESMDVVDIEGMEEEPIAFGLKAIRVKVVVPDAEGGTDALEDALKEVD
EVNQVEVVSASRTL

Sequences:

>Translated_94_residues
MIVVSKVLVDLKVLPESADVDYEELKEAIREKLESMDVVDIEGMEEEPIAFGLKAIRVKVVVPDAEGGTDALEDALKEVD
EVNQVEVVSASRTL
>Mature_94_residues
MIVVSKVLVDLKVLPESADVDYEELKEAIREKLESMDVVDIEGMEEEPIAFGLKAIRVKVVVPDAEGGTDALEDALKEVD
EVNQVEVVSASRTL

Specific function: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA

COG id: COG2092

COG function: function code J; Translation elongation factor EF-1beta

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-1-beta/EF-1-delta family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EF1B_METKA (Q8TYN8)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613542.1
- ProteinModelPortal:   Q8TYN8
- SMR:   Q8TYN8
- GeneID:   1477558
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0255
- NMPDR:   fig|190192.1.peg.255
- HOGENOM:   HBG541037
- OMA:   DEPLAFG
- BioCyc:   MKAN190192:MK0255-MONOMER
- HAMAP:   MF_00043
- InterPro:   IPR014717
- InterPro:   IPR004542
- InterPro:   IPR014038
- Gene3D:   G3DSA:3.30.70.60
- PIRSF:   PIRSF006521
- SMART:   SM00888
- TIGRFAMs:   TIGR00489

Pfam domain/function: PF00736 EF1_GNE; SSF54984 Transl_elong_EF1B_B/D_G_exch

EC number: NA

Molecular weight: Translated: 10298; Mature: 10298

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVSKVLVDLKVLPESADVDYEELKEAIREKLESMDVVDIEGMEEEPIAFGLKAIRVKV
CEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCEEEEEEE
VVPDAEGGTDALEDALKEVDEVNQVEVVSASRTL
EEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MIVVSKVLVDLKVLPESADVDYEELKEAIREKLESMDVVDIEGMEEEPIAFGLKAIRVKV
CEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCEEEEEEE
VVPDAEGGTDALEDALKEVDEVNQVEVVSASRTL
EEECCCCCHHHHHHHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014