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The map label for this gene is HypD [C]

Identifier: 20093666

GI number: 20093666

Start: 213461

End: 214513

Strand: Reverse

Name: HypD [C]

Synonym: MK0226

Alternate gene names: 20093666

Gene position: 214513-213461 (Counterclockwise)

Preceding gene: 20093667

Following gene: 20093665

Centisome position: 12.66

GC content: 61.44

Gene sequence:

>1053_bases
TTGAAAATGACACGTCGGGAGTTCGTGAGAAAGCTCGTCCGTCGAATCCATAAGGAGGCCGAGACCCTCGATCGTGATGT
GACGATCATGCACGTGTGTGGATCCCATGAACGGACTATAGTCGAACACGGTCTCAGATCGTTGCTTCCCGAGAACGTCC
GTTTAGTCTGCGGTCCAGGGTGCCCCGTGTGTGTGACCACTACGGGAGAGCTCGCCGCGGCCATAAAGGCTGCGGAAGAT
GGCATGGTCGTGTGCGCTTTCGGGGACGTGTACAGGGTCCCCACTCCTGTCGGATCCCTCTCCTCATGCGATGGGGACGT
CAGGGTGGTCCAGAGCGTTAGGAAGGCCGAGGAGATCGCCGAGTCCGAGGACCGTGATGTCCTCTACCTGGCGGTAGGGT
TCGAGACTACGGCACCGACCACCGCGGCCGTGCTCCTCGATGACCCGCCCTCCAACTTCTACGTGCTGTCGGCTCACCGG
TTGATACCACCTGCGATGGAGTGGTTGCTGGAGTCGGGCGAGTGCCGTCTCGACGCGTTCATATGTCCCGGTCACGTGTC
CACGATCATCGGGACGGGGCCCTACGAGTCCGTAGCCCGGGAGCTCCCGTGCGTGGTCGCCGGCTTCGAGCCCGAGGACG
TTCTGATCGCGGTACTGGCGTGCCTCAAGATGCTCAGAAGGGGACGTGTGGGAGTCACCAACGAGTACCTCAGGGCAGTC
GAGGACAGGGGGAACCCGGTCGCGAAGGAACTGATGGAAAGGGCGTTCGAGCCCGAAGATAGGCCGTGGCGGGGTTTCCC
GACCATCCCCGAGTCGGCGTTGAAGCTGCGTGAGGACCTCGCAGATCACGATGCGATTGAGATTGGAATACGGCCGGATT
ACACCCTGGGACACGACGAATCCTGCATATGTGATCGGATACTGCGAGGGTTGGCCGAGCCCCGGGACTGCCCGTTGTTC
GGCACGAAATGTACTCCGACGGATCCCGTAGGCCCGTGCATGGTGTCGGAGGAAGGCCCGTGTTTCATAGAGTACAGGTT
CGGCGGAGGGTGA

Upstream 100 bases:

>100_bases
ATCGTTCACACGGGTTTCGCGATTCAGAAGCTAGATGAGGAGGAAGCACGAGCGTCCCTTGAGATCTGGGAAGAAGTTCT
GAAACACATCGAGGAGGAGC

Downstream 100 bases:

>100_bases
GGCATGTCCACCGACGAGTGGCTTCGAGAACTGGAGCGGGCTCTGAAACGCGCGGAAGATACTGACATGATCCTGAACCC
CGCGCTCGGAATCGGTGTCG

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKMTRREFVRKLVRRIHKEAETLDRDVTIMHVCGSHERTIVEHGLRSLLPENVRLVCGPGCPVCVTTTGELAAAIKAAED
GMVVCAFGDVYRVPTPVGSLSSCDGDVRVVQSVRKAEEIAESEDRDVLYLAVGFETTAPTTAAVLLDDPPSNFYVLSAHR
LIPPAMEWLLESGECRLDAFICPGHVSTIIGTGPYESVARELPCVVAGFEPEDVLIAVLACLKMLRRGRVGVTNEYLRAV
EDRGNPVAKELMERAFEPEDRPWRGFPTIPESALKLREDLADHDAIEIGIRPDYTLGHDESCICDRILRGLAEPRDCPLF
GTKCTPTDPVGPCMVSEEGPCFIEYRFGGG

Sequences:

>Translated_350_residues
MKMTRREFVRKLVRRIHKEAETLDRDVTIMHVCGSHERTIVEHGLRSLLPENVRLVCGPGCPVCVTTTGELAAAIKAAED
GMVVCAFGDVYRVPTPVGSLSSCDGDVRVVQSVRKAEEIAESEDRDVLYLAVGFETTAPTTAAVLLDDPPSNFYVLSAHR
LIPPAMEWLLESGECRLDAFICPGHVSTIIGTGPYESVARELPCVVAGFEPEDVLIAVLACLKMLRRGRVGVTNEYLRAV
EDRGNPVAKELMERAFEPEDRPWRGFPTIPESALKLREDLADHDAIEIGIRPDYTLGHDESCICDRILRGLAEPRDCPLF
GTKCTPTDPVGPCMVSEEGPCFIEYRFGGG
>Mature_350_residues
MKMTRREFVRKLVRRIHKEAETLDRDVTIMHVCGSHERTIVEHGLRSLLPENVRLVCGPGCPVCVTTTGELAAAIKAAED
GMVVCAFGDVYRVPTPVGSLSSCDGDVRVVQSVRKAEEIAESEDRDVLYLAVGFETTAPTTAAVLLDDPPSNFYVLSAHR
LIPPAMEWLLESGECRLDAFICPGHVSTIIGTGPYESVARELPCVVAGFEPEDVLIAVLACLKMLRRGRVGVTNEYLRAV
EDRGNPVAKELMERAFEPEDRPWRGFPTIPESALKLREDLADHDAIEIGIRPDYTLGHDESCICDRILRGLAEPRDCPLF
GTKCTPTDPVGPCMVSEEGPCFIEYRFGGG

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=353, Percent_Identity=37.9603399433428, Blast_Score=217, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 38467; Mature: 38467

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMTRREFVRKLVRRIHKEAETLDRDVTIMHVCGSHERTIVEHGLRSLLPENVRLVCGPG
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
CPVCVTTTGELAAAIKAAEDGMVVCAFGDVYRVPTPVGSLSSCDGDVRVVQSVRKAEEIA
CCEEEECCHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ESEDRDVLYLAVGFETTAPTTAAVLLDDPPSNFYVLSAHRLIPPAMEWLLESGECRLDAF
CCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEE
ICPGHVSTIIGTGPYESVARELPCVVAGFEPEDVLIAVLACLKMLRRGRVGVTNEYLRAV
ECCCHHHHEECCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EDRGNPVAKELMERAFEPEDRPWRGFPTIPESALKLREDLADHDAIEIGIRPDYTLGHDE
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
SCICDRILRGLAEPRDCPLFGTKCTPTDPVGPCMVSEEGPCFIEYRFGGG
HHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MKMTRREFVRKLVRRIHKEAETLDRDVTIMHVCGSHERTIVEHGLRSLLPENVRLVCGPG
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
CPVCVTTTGELAAAIKAAEDGMVVCAFGDVYRVPTPVGSLSSCDGDVRVVQSVRKAEEIA
CCEEEECCHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ESEDRDVLYLAVGFETTAPTTAAVLLDDPPSNFYVLSAHRLIPPAMEWLLESGECRLDAF
CCCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEE
ICPGHVSTIIGTGPYESVARELPCVVAGFEPEDVLIAVLACLKMLRRGRVGVTNEYLRAV
ECCCHHHHEECCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EDRGNPVAKELMERAFEPEDRPWRGFPTIPESALKLREDLADHDAIEIGIRPDYTLGHDE
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
SCICDRILRGLAEPRDCPLFGTKCTPTDPVGPCMVSEEGPCFIEYRFGGG
HHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]