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The map label for this gene is Mra1

Identifier: 20093642

GI number: 20093642

Start: 195008

End: 195703

Strand: Reverse

Name: Mra1

Synonym: MK0202

Alternate gene names: NA

Gene position: 195703-195008 (Counterclockwise)

Preceding gene: 20093645

Following gene: 20093640

Centisome position: 11.55

GC content: 60.63

Gene sequence:

>696_bases
ATGCCGCGTCTTTGTTTCGTGCTAGCGGAGTCGGAGCTGGAGTTCATCCCGCCCAAGCTCAGGGGCCATCAACACGTGGT
GAGGTGGGCGAAACGACGTGGGAAAAAGCCGGGAGAATGTCTCCTCATAGCGAGCAAGCATCACGTAGCCATGCGCGATA
AACGGCTCCCGGAGCGTGACCGTCGGGGTCGCCCCGACATAGTTCACGTGACGCTGCTTCACGTACTGGACTCCCCCGCA
TCCCGGGAGAACGCCCTAGACGTGTACGTACACACCAGACATGACCGCGTCATATGGTTCCGTGGAGACGTCAGGCTACC
GAGGGATCAGTATCGGTTCATTGGGCTCATGGAGCAGGTCCTCAAGGAGGGTCAGGCGCCTCCGGATTCCGATGAGCCGC
TGATAGAGGTCCTGGATGTCAGCGTGTGGGACGTGCTGGAGGCCAACGAGGTCAACGTGTTACTTTCCGAACGAGGCGAT
CTGATCGAACCCGTCGGCTATATGGCCGGGCTCCTGGACGCCGGCGTGGAAAGGATAGGAGTCGTGGTGGGTGGCTTCCC
GAAGGGGGACTTCTCGGAGGAGTTCTACGATCGTGCGGACGATGTCGTTCGAATATACGACGAACCCCTGGACGCGTGGA
CGGTGGCTGCACGAATCGTCACGGCCTTCGAGCTGGCCGCCGGCATCTTGGGTTAG

Upstream 100 bases:

>100_bases
GCAGGTACCGGATGCACTTTAGGTGGACGGCTCTATCATCTCCCGTGATCGTGCCGTCGATATCCGTGATGACGAGGGAC
GTCACGGGGGTAGCCCCCGC

Downstream 100 bases:

>100_bases
CCCTTCACCTCGATACCTTCGATGAGCTCCCGTGGAATCTCTATTTCGTCACCCTCCTCGATTTCTCCCTCCGACATCAT
GCGGGCCAGCCAAGTGTTGA

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPRLCFVLAESELEFIPPKLRGHQHVVRWAKRRGKKPGECLLIASKHHVAMRDKRLPERDRRGRPDIVHVTLLHVLDSPA
SRENALDVYVHTRHDRVIWFRGDVRLPRDQYRFIGLMEQVLKEGQAPPDSDEPLIEVLDVSVWDVLEANEVNVLLSERGD
LIEPVGYMAGLLDAGVERIGVVVGGFPKGDFSEEFYDRADDVVRIYDEPLDAWTVAARIVTAFELAAGILG

Sequences:

>Translated_231_residues
MPRLCFVLAESELEFIPPKLRGHQHVVRWAKRRGKKPGECLLIASKHHVAMRDKRLPERDRRGRPDIVHVTLLHVLDSPA
SRENALDVYVHTRHDRVIWFRGDVRLPRDQYRFIGLMEQVLKEGQAPPDSDEPLIEVLDVSVWDVLEANEVNVLLSERGD
LIEPVGYMAGLLDAGVERIGVVVGGFPKGDFSEEFYDRADDVVRIYDEPLDAWTVAARIVTAFELAAGILG
>Mature_230_residues
PRLCFVLAESELEFIPPKLRGHQHVVRWAKRRGKKPGECLLIASKHHVAMRDKRLPERDRRGRPDIVHVTLLHVLDSPAS
RENALDVYVHTRHDRVIWFRGDVRLPRDQYRFIGLMEQVLKEGQAPPDSDEPLIEVLDVSVWDVLEANEVNVLLSERGDL
IEPVGYMAGLLDAGVERIGVVVGGFPKGDFSEEFYDRADDVVRIYDEPLDAWTVAARIVTAFELAAGILG

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing [H]

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family [H]

Homologues:

Organism=Homo sapiens, GI194328699, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323215, Length=171, Percent_Identity=33.9181286549708, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639698, Length=176, Percent_Identity=30.6818181818182, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005304 [H]

Pfam domain/function: PF03587 EMG1 [H]

EC number: NA

Molecular weight: Translated: 26201; Mature: 26070

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLCFVLAESELEFIPPKLRGHQHVVRWAKRRGKKPGECLLIASKHHVAMRDKRLPERD
CCCEEEEEECCCCHHCCCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCHHH
RRGRPDIVHVTLLHVLDSPASRENALDVYVHTRHDRVIWFRGDVRLPRDQYRFIGLMEQV
CCCCCCEEHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
LKEGQAPPDSDEPLIEVLDVSVWDVLEANEVNVLLSERGDLIEPVGYMAGLLDAGVERIG
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VVVGGFPKGDFSEEFYDRADDVVRIYDEPLDAWTVAARIVTAFELAAGILG
EEEECCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRLCFVLAESELEFIPPKLRGHQHVVRWAKRRGKKPGECLLIASKHHVAMRDKRLPERD
CCEEEEEECCCCHHCCCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCHHH
RRGRPDIVHVTLLHVLDSPASRENALDVYVHTRHDRVIWFRGDVRLPRDQYRFIGLMEQV
CCCCCCEEHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHH
LKEGQAPPDSDEPLIEVLDVSVWDVLEANEVNVLLSERGDLIEPVGYMAGLLDAGVERIG
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VVVGGFPKGDFSEEFYDRADDVVRIYDEPLDAWTVAARIVTAFELAAGILG
EEEECCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA