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The map label for this gene is ppcA

Identifier: 20093630

GI number: 20093630

Start: 182418

End: 184016

Strand: Direct

Name: ppcA

Synonym: MK0190

Alternate gene names: 20093630

Gene position: 182418-184016 (Clockwise)

Preceding gene: 20093629

Following gene: 20093639

Centisome position: 10.76

GC content: 59.29

Gene sequence:

>1599_bases
GTGGAGAAAGTCCGAGAAGCTCGAATTGCACGGACGCTGGCCACCCAGCATCCTGACGCGACGAAGTTCGTGAGGGTGCA
GGAGGAGCCTGAGGAGGCCGTGGAGTGTCTGGTCGAGCTCGGCGCGGAGGAATACATGGTGGATTTCGAGGGCAAGCTGA
CGCCGTACCTGCAGCCCATTCAGGTCCTCATGGAACTGTACGACGCCGGCGTTCGGGTGGGAGAGGAACGTTTCGTGATC
GTCAGGGTACCTAGTGCGACGAAGGAGAACGTACTACGCCAAGTCCAGGCCCTGCTGGGTGTAATGGAAGCCAACTCGGA
GTTGCTTAAGGAGGACCCAGACGCCCGCGGGATCTTCGAGGTAGTACATCCCATGACGTCCTCGCCCGAAGAGCTCGTGG
AAACAGTGGACAGGATCTCATACGCGCGCAGGTTCGCGTCCCGTGAGCTAGACGTACCACTTAAGGCGGGAAACCTCCGG
ATCATCCCACTTATCGAGGAAGTTCCCGAACTCCTAGACATTCGCAACATTCTAACGGGCTACGTGGAAGGGATGCGTGA
AATCGGGATGGACGTCAGCTACCTCAGGGTGTTCATCGGACGCTCCGACCCCGCGCTATCCTACGGGCATCTTCCGGCGG
TCCTCGCCTGCAAGCTGGCCATTTTCGAAGTGTATGAGCTGTCGGACGAACTAGGTGTCCCGATGGCGCCTATCTTAGGA
GGCGGGTGCCTGCCGTTCCGCGGCCATATTAGGCCGGGAATGGAAGAAGAGTTCGTAGAGGAGTACGCGGGCACCGCCAC
GTACACCGTACAATCCGGATTCCGGTACGATCACGACCGGGAAAAGGCCGTTGCGTCCATCCGCCGCATTAACGAGCTCG
CCGCGAACGACCCACTCCAACTTTCCGGGGACGACATCGAGTACCTCGTCTTAGCCACCGCGATCTTCATGAAGCACTAC
CTCAGCGTGTTCTTCCGTTGCATAGGTACGCTGAACATCGTCGCCGACATGATCCCCAATACAAGGGACCGATTGGCACG
TAAGGGGCCCGTAGGGTACGCGCGGGACATTCCCGAACCTGACCGTGTCGGAGCACAGTGTAAGGACCTTGGAGATGTGG
GTCGTGAGTTATACCGCGAACTGCGCCGAATGAGGGTCGAGAAGCTGCCCGAGCTGCCACGCGCGATCAAATTCACGGGA
GCCTGCTACACCGTCGGGATGCCACCGGAGCTCATCGGAACCGGAAGGGGACTCGCGGAGATCGAGGAGCGGCTAGGTGA
AGATGCGTTGGACGCTGTGATCTCACGATTGTACCCCATGCTACGCGAGGATCTGCAGTTCGCAGTGGAGTACACCTTCC
TCGAAACGGCCGGATCCGTCCTACCGTCGTCCGGAGTAGCGATGGTCAACACCGACCTGGAGTACTGCGTCGAGTACCTC
GACCTGGAACCCCCATCCGACTTCGAGTACCAGAACCTGGTACACACGTTGGAACCGTACCTCAGGTACGTGGTCTCGGA
GGGTGGTGTAGAGGAAGTCAACCCGTTCGTGAGGGATCTCCTCCTCGAGATGGGCCGAATGCGTGGATCACTCGGATGA

Upstream 100 bases:

>100_bases
AAACACGCCCGGGACGTCCGGAAGTCCCTAGAGGTAACATTTTGAGTATTCGAGGCGGATAGTCGGCGGGTGTCTCGAGT
TGAACGAGGTGATCAGGGAG

Downstream 100 bases:

>100_bases
CGGGGACGGATTCAAGTGCACGGCCTCGAAGATTTCCTTGACTAGTTCAGGGCCCACACCGAGGGCCACGCAATGGTGGT
TCCCCCGCGGCTCGAACTCC

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MEKVREARIARTLATQHPDATKFVRVQEEPEEAVECLVELGAEEYMVDFEGKLTPYLQPIQVLMELYDAGVRVGEERFVI
VRVPSATKENVLRQVQALLGVMEANSELLKEDPDARGIFEVVHPMTSSPEELVETVDRISYARRFASRELDVPLKAGNLR
IIPLIEEVPELLDIRNILTGYVEGMREIGMDVSYLRVFIGRSDPALSYGHLPAVLACKLAIFEVYELSDELGVPMAPILG
GGCLPFRGHIRPGMEEEFVEEYAGTATYTVQSGFRYDHDREKAVASIRRINELAANDPLQLSGDDIEYLVLATAIFMKHY
LSVFFRCIGTLNIVADMIPNTRDRLARKGPVGYARDIPEPDRVGAQCKDLGDVGRELYRELRRMRVEKLPELPRAIKFTG
ACYTVGMPPELIGTGRGLAEIEERLGEDALDAVISRLYPMLREDLQFAVEYTFLETAGSVLPSSGVAMVNTDLEYCVEYL
DLEPPSDFEYQNLVHTLEPYLRYVVSEGGVEEVNPFVRDLLLEMGRMRGSLG

Sequences:

>Translated_532_residues
MEKVREARIARTLATQHPDATKFVRVQEEPEEAVECLVELGAEEYMVDFEGKLTPYLQPIQVLMELYDAGVRVGEERFVI
VRVPSATKENVLRQVQALLGVMEANSELLKEDPDARGIFEVVHPMTSSPEELVETVDRISYARRFASRELDVPLKAGNLR
IIPLIEEVPELLDIRNILTGYVEGMREIGMDVSYLRVFIGRSDPALSYGHLPAVLACKLAIFEVYELSDELGVPMAPILG
GGCLPFRGHIRPGMEEEFVEEYAGTATYTVQSGFRYDHDREKAVASIRRINELAANDPLQLSGDDIEYLVLATAIFMKHY
LSVFFRCIGTLNIVADMIPNTRDRLARKGPVGYARDIPEPDRVGAQCKDLGDVGRELYRELRRMRVEKLPELPRAIKFTG
ACYTVGMPPELIGTGRGLAEIEERLGEDALDAVISRLYPMLREDLQFAVEYTFLETAGSVLPSSGVAMVNTDLEYCVEYL
DLEPPSDFEYQNLVHTLEPYLRYVVSEGGVEEVNPFVRDLLLEMGRMRGSLG
>Mature_532_residues
MEKVREARIARTLATQHPDATKFVRVQEEPEEAVECLVELGAEEYMVDFEGKLTPYLQPIQVLMELYDAGVRVGEERFVI
VRVPSATKENVLRQVQALLGVMEANSELLKEDPDARGIFEVVHPMTSSPEELVETVDRISYARRFASRELDVPLKAGNLR
IIPLIEEVPELLDIRNILTGYVEGMREIGMDVSYLRVFIGRSDPALSYGHLPAVLACKLAIFEVYELSDELGVPMAPILG
GGCLPFRGHIRPGMEEEFVEEYAGTATYTVQSGFRYDHDREKAVASIRRINELAANDPLQLSGDDIEYLVLATAIFMKHY
LSVFFRCIGTLNIVADMIPNTRDRLARKGPVGYARDIPEPDRVGAQCKDLGDVGRELYRELRRMRVEKLPELPRAIKFTG
ACYTVGMPPELIGTGRGLAEIEERLGEDALDAVISRLYPMLREDLQFAVEYTFLETAGSVLPSSGVAMVNTDLEYCVEYL
DLEPPSDFEYQNLVHTLEPYLRYVVSEGGVEEVNPFVRDLLLEMGRMRGSLG

Specific function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG1892

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CAPPA_METKA (Q8TYV1)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_613477.1
- ProteinModelPortal:   Q8TYV1
- GeneID:   1477493
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0190
- NMPDR:   fig|190192.1.peg.190
- HOGENOM:   HBG538207
- OMA:   MCTQHPD
- ProtClustDB:   PRK13655
- BioCyc:   MKAN190192:MK0190-MONOMER
- BRENDA:   4.1.1.31
- HAMAP:   MF_01904
- InterPro:   IPR021135
- InterPro:   IPR007566
- InterPro:   IPR015813
- PIRSF:   PIRSF006677
- TIGRFAMs:   TIGR02751

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 59778; Mature: 59778

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVREARIARTLATQHPDATKFVRVQEEPEEAVECLVELGAEEYMVDFEGKLTPYLQPI
CCHHHHHHHHHHHHHCCCCCHHEEEECCCHHHHHHHHHHHCCHHEEEECCCCCCHHHHHH
QVLMELYDAGVRVGEERFVIVRVPSATKENVLRQVQALLGVMEANSELLKEDPDARGIFE
HHHHHHHHHHCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHH
VVHPMTSSPEELVETVDRISYARRFASRELDVPLKAGNLRIIPLIEEVPELLDIRNILTG
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEHHHHHHHHHHHHHHHHH
YVEGMREIGMDVSYLRVFIGRSDPALSYGHLPAVLACKLAIFEVYELSDELGVPMAPILG
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
GGCLPFRGHIRPGMEEEFVEEYAGTATYTVQSGFRYDHDREKAVASIRRINELAANDPLQ
CCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
LSGDDIEYLVLATAIFMKHYLSVFFRCIGTLNIVADMIPNTRDRLARKGPVGYARDIPEP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCH
DRVGAQCKDLGDVGRELYRELRRMRVEKLPELPRAIKFTGACYTVGMPPELIGTGRGLAE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCEEECCCCHHHHCCCCCHHH
IEERLGEDALDAVISRLYPMLREDLQFAVEYTFLETAGSVLPSSGVAMVNTDLEYCVEYL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHH
DLEPPSDFEYQNLVHTLEPYLRYVVSEGGVEEVNPFVRDLLLEMGRMRGSLG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKVREARIARTLATQHPDATKFVRVQEEPEEAVECLVELGAEEYMVDFEGKLTPYLQPI
CCHHHHHHHHHHHHHCCCCCHHEEEECCCHHHHHHHHHHHCCHHEEEECCCCCCHHHHHH
QVLMELYDAGVRVGEERFVIVRVPSATKENVLRQVQALLGVMEANSELLKEDPDARGIFE
HHHHHHHHHHCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHH
VVHPMTSSPEELVETVDRISYARRFASRELDVPLKAGNLRIIPLIEEVPELLDIRNILTG
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEEEEHHHHHHHHHHHHHHHHH
YVEGMREIGMDVSYLRVFIGRSDPALSYGHLPAVLACKLAIFEVYELSDELGVPMAPILG
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
GGCLPFRGHIRPGMEEEFVEEYAGTATYTVQSGFRYDHDREKAVASIRRINELAANDPLQ
CCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
LSGDDIEYLVLATAIFMKHYLSVFFRCIGTLNIVADMIPNTRDRLARKGPVGYARDIPEP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCH
DRVGAQCKDLGDVGRELYRELRRMRVEKLPELPRAIKFTGACYTVGMPPELIGTGRGLAE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCEEECCCCHHHHCCCCCHHH
IEERLGEDALDAVISRLYPMLREDLQFAVEYTFLETAGSVLPSSGVAMVNTDLEYCVEYL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHH
DLEPPSDFEYQNLVHTLEPYLRYVVSEGGVEEVNPFVRDLLLEMGRMRGSLG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014