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The map label for this gene is RibD [C]

Identifier: 20093538

GI number: 20093538

Start: 90768

End: 91475

Strand: Direct

Name: RibD [C]

Synonym: MK0098

Alternate gene names: 20093538

Gene position: 90768-91475 (Clockwise)

Preceding gene: 20093537

Following gene: 20093539

Centisome position: 5.36

GC content: 63.98

Gene sequence:

>708_bases
GTGCCGCGGCCGAAGGTCCTGTACAACGTTGGGATGACGGCGGACGGGAAGGTCGTGACCGCCGCCGGAGATTCCAGGAT
CTCGGGCGAAGAGGATCTCAAAGAGGTCCACAGGTTGAGAGCAGAACACGACGCGGTGGCCGTGGGGATCAACACGGTGC
GGAAGGACGACCCCATGCTGAACGTGCGGTTGGTGGAGGGAGAAGACCCCATCCGAGTCGTGTTCGACACCGAGTGCTCC
ATTCCGCTCGACTGTCGCCTAGTTCGCACCGCTCGGGATATCCCCACGGTCGTGCTCTGTGCCGAGGCCGACCCGGGTCG
CGTCGAGAAGCTCGAGAAAAGAGGTGTGAAGGTGGAGGAAGTCGGTGCCTGTGAGGACGGCGTCGATGTGGAGCGTGGGC
TGGAGCTGCTCTACGATATGGGAGTACGAACCTTGCTACTCGAAGGTGGGCCAACGCTGGCCTGGTCCTTCTTGAAGCGC
GGCCTGATCGACGAGTTCCGTGTGGCCGTGGCTCCCGTGCTCGTGGGCGGGTCCGACGCGTTGACGCCCGTAGAGGGTGA
GGGGTTCCCGCGTGTCGATCTCGGAGTGGGCCTGGAATTAAAACGGGTGGAGCGAGTGGGGCGCGACGTGGTGCTCTGGT
ACGAGGTTTCCGGATCCGCCGCCGACCTGGCCTCCGAACACGAAGAGGCTCGGGGGAGATCGTCATGA

Upstream 100 bases:

>100_bases
CCCATCGTGTGCTCACCGAGAGACGCACTCGAGGCGTTCGAGCACGGTGTTGCGGACGTCCTGTGGATCGAAGGCTACAT
GATCGAGCGGGGGTGAGCTC

Downstream 100 bases:

>100_bases
AGTGTCCGGAGTGCGGGACCGAGATGCGATCGGAGCTCCGGGACGATGGGGTGGAACTCCTCAGGTGTCCCGAGTGCGGC
AAGGAGATCAAGCGCGTCCC

Product: pyrimidine reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPRPKVLYNVGMTADGKVVTAAGDSRISGEEDLKEVHRLRAEHDAVAVGINTVRKDDPMLNVRLVEGEDPIRVVFDTECS
IPLDCRLVRTARDIPTVVLCAEADPGRVEKLEKRGVKVEEVGACEDGVDVERGLELLYDMGVRTLLLEGGPTLAWSFLKR
GLIDEFRVAVAPVLVGGSDALTPVEGEGFPRVDLGVGLELKRVERVGRDVVLWYEVSGSAADLASEHEEARGRSS

Sequences:

>Translated_235_residues
MPRPKVLYNVGMTADGKVVTAAGDSRISGEEDLKEVHRLRAEHDAVAVGINTVRKDDPMLNVRLVEGEDPIRVVFDTECS
IPLDCRLVRTARDIPTVVLCAEADPGRVEKLEKRGVKVEEVGACEDGVDVERGLELLYDMGVRTLLLEGGPTLAWSFLKR
GLIDEFRVAVAPVLVGGSDALTPVEGEGFPRVDLGVGLELKRVERVGRDVVLWYEVSGSAADLASEHEEARGRSS
>Mature_234_residues
PRPKVLYNVGMTADGKVVTAAGDSRISGEEDLKEVHRLRAEHDAVAVGINTVRKDDPMLNVRLVEGEDPIRVVFDTECSI
PLDCRLVRTARDIPTVVLCAEADPGRVEKLEKRGVKVEEVGACEDGVDVERGLELLYDMGVRTLLLEGGPTLAWSFLKRG
LIDEFRVAVAPVLVGGSDALTPVEGEGFPRVDLGVGLELKRVERVGRDVVLWYEVSGSAADLASEHEEARGRSS

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 25540; Mature: 25409

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPKVLYNVGMTADGKVVTAAGDSRISGEEDLKEVHRLRAEHDAVAVGINTVRKDDPML
CCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHCCCCCCEE
NVRLVEGEDPIRVVFDTECSIPLDCRLVRTARDIPTVVLCAEADPGRVEKLEKRGVKVEE
EEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCCCEEEEEECCCCHHHHHHHHCCCCEEC
VGACEDGVDVERGLELLYDMGVRTLLLEGGPTLAWSFLKRGLIDEFRVAVAPVLVGGSDA
CCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHEEEECCCCC
LTPVEGEGFPRVDLGVGLELKRVERVGRDVVLWYEVSGSAADLASEHEEARGRSS
CCCCCCCCCCEEECCCCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRPKVLYNVGMTADGKVVTAAGDSRISGEEDLKEVHRLRAEHDAVAVGINTVRKDDPML
CCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHCCCCCCEE
NVRLVEGEDPIRVVFDTECSIPLDCRLVRTARDIPTVVLCAEADPGRVEKLEKRGVKVEE
EEEEECCCCCEEEEEECCCCCCCCEEEEEHHCCCCEEEEEECCCCHHHHHHHHCCCCEEC
VGACEDGVDVERGLELLYDMGVRTLLLEGGPTLAWSFLKRGLIDEFRVAVAPVLVGGSDA
CCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHEEEECCCCC
LTPVEGEGFPRVDLGVGLELKRVERVGRDVVLWYEVSGSAADLASEHEEARGRSS
CCCCCCCCCCEEECCCCCCHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]