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The map label for this gene is 20093485

Identifier: 20093485

GI number: 20093485

Start: 41815

End: 42918

Strand: Direct

Name: 20093485

Synonym: MK0045

Alternate gene names: NA

Gene position: 41815-42918 (Clockwise)

Preceding gene: 20093481

Following gene: 20093486

Centisome position: 2.47

GC content: 61.5

Gene sequence:

>1104_bases
ATGCCACCGAAATGGTACAGGCACGTGATGAGAGTGCTCTCCGAATCGCACGTGGTGTTGGAGGTTCGAGACGTGCGATA
TCCGGAGGAGACACGGTGGGAAAAGCTCCCCAGACTGGAGGACGTGTTCGACTTCACCCGGGTGGTCGTGCTCAACAAGG
CCGACCTGGTCCCCCGGGCCGAGACCGAGCGTGTGAAGGAGGAAGTGGAGCTCGAGGAGGACGTACCTGCGGTGTACGTA
AGCGCACGCGAGCGCATGGGTTTCCGGCACCTCCGTAGGACCATCTACGAGGTAGCGCCGGAAGACGTCGAGACCGTGAG
AGTGGGTGTAGTAGGGTTTCAGAACGTCGGTAAGTCCACGATAATTAACGCATTGACCCGGAGGAGTGCCGCAGAAACCT
CTCGACGTGCGGGATACACCCGCGGAAAGCAGTGGGTACGCGGTGGTAGGAAACTGTTGGTCATCGACTCGCCGGGTGTG
ATCCCGACCGACGAGGCTGCGGCCGAGGCCGTGGCGCTGGATCCAGACGTCCTGGAGGATCCCGTAGAGCCGGCGTTAGG
CGTGATCGAGCGCGTCGTCCGCGAGTATCCAGGGGCACTGTCCGACAAATTCGGTATCGATGAATCGATGGATCCGGAGA
GGATCCTCCGGGATATCTCAGAACGCTTGGGTAAAGACCTCAGAACGACCGCGAAACTACTCCTCCGGGAGTGGGTGGAC
GGCAGCCTGGTGGAGATTTATCGGACCACGCGGGCCGACCTAGCTGAGACTTCGGAGCTAGAGGTAGGTGGCACCGCCCA
GCGCTTAGTGGAGGAGACTCTCCGTGAGATCGAGGAAGTGGTACCCGAAGGTATCCCCCCTAGCGCCGCGACGGTCCGGG
GGATTCTAACGAGGCTGGCCCACGGAGAGAACGTGGACGGCGTGGGATTCGGCACCATAAGGCTGGGTGAATACGGTGTG
GGAGTGTCCGTCGGCGACCGGTACTACGATCGAATGGTTAGGAGACTGCGTCGTGAACTGGGGGGCGAAGTGATCTCTGA
GGAGCGGTTCAGAGTGGGCGCCAACGGGCGGAAGGCGGTGGCACTGGTGACCAAGGGTCGGTAG

Upstream 100 bases:

>100_bases
GTTGGAGCGTCTCGAGGTCCCGGAGATCGGATTTAATAGCCCCCACCCCCGTGTTGAGGTCGAGTTAACGGATACAAAAA
CCGCTCGGGAGTGGCGGTAC

Downstream 100 bases:

>100_bases
CGCGGGCCGGTTTCCTCACCTTCTGCCCTGATCGGACCCCATGGCCCTCCCCATCCCCTCGAATCAGCGCGGGGAGTTCT
CCGCATCTCCGGCCGTACTC

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MPPKWYRHVMRVLSESHVVLEVRDVRYPEETRWEKLPRLEDVFDFTRVVVLNKADLVPRAETERVKEEVELEEDVPAVYV
SARERMGFRHLRRTIYEVAPEDVETVRVGVVGFQNVGKSTIINALTRRSAAETSRRAGYTRGKQWVRGGRKLLVIDSPGV
IPTDEAAAEAVALDPDVLEDPVEPALGVIERVVREYPGALSDKFGIDESMDPERILRDISERLGKDLRTTAKLLLREWVD
GSLVEIYRTTRADLAETSELEVGGTAQRLVEETLREIEEVVPEGIPPSAATVRGILTRLAHGENVDGVGFGTIRLGEYGV
GVSVGDRYYDRMVRRLRRELGGEVISEERFRVGANGRKAVALVTKGR

Sequences:

>Translated_367_residues
MPPKWYRHVMRVLSESHVVLEVRDVRYPEETRWEKLPRLEDVFDFTRVVVLNKADLVPRAETERVKEEVELEEDVPAVYV
SARERMGFRHLRRTIYEVAPEDVETVRVGVVGFQNVGKSTIINALTRRSAAETSRRAGYTRGKQWVRGGRKLLVIDSPGV
IPTDEAAAEAVALDPDVLEDPVEPALGVIERVVREYPGALSDKFGIDESMDPERILRDISERLGKDLRTTAKLLLREWVD
GSLVEIYRTTRADLAETSELEVGGTAQRLVEETLREIEEVVPEGIPPSAATVRGILTRLAHGENVDGVGFGTIRLGEYGV
GVSVGDRYYDRMVRRLRRELGGEVISEERFRVGANGRKAVALVTKGR
>Mature_366_residues
PPKWYRHVMRVLSESHVVLEVRDVRYPEETRWEKLPRLEDVFDFTRVVVLNKADLVPRAETERVKEEVELEEDVPAVYVS
ARERMGFRHLRRTIYEVAPEDVETVRVGVVGFQNVGKSTIINALTRRSAAETSRRAGYTRGKQWVRGGRKLLVIDSPGVI
PTDEAAAEAVALDPDVLEDPVEPALGVIERVVREYPGALSDKFGIDESMDPERILRDISERLGKDLRTTAKLLLREWVDG
SLVEIYRTTRADLAETSELEVGGTAQRLVEETLREIEEVVPEGIPPSAATVRGILTRLAHGENVDGVGFGTIRLGEYGVG
VSVGDRYYDRMVRRLRRELGGEVISEERFRVGANGRKAVALVTKGR

Specific function: Unknown

COG id: COG1161

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI7019419, Length=281, Percent_Identity=29.1814946619217, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI296317324, Length=279, Percent_Identity=27.2401433691756, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI9506611, Length=279, Percent_Identity=27.2401433691756, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534827, Length=278, Percent_Identity=26.978417266187, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32563985, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990926, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563983, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324381, Length=168, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922460, Length=259, Percent_Identity=28.1853281853282, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28572990, Length=279, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023179
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR000795 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 41279; Mature: 41147

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKWYRHVMRVLSESHVVLEVRDVRYPEETRWEKLPRLEDVFDFTRVVVLNKADLVPRA
CCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCH
ETERVKEEVELEEDVPAVYVSARERMGFRHLRRTIYEVAPEDVETVRVGVVGFQNVGKST
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHH
IINALTRRSAAETSRRAGYTRGKQWVRGGRKLLVIDSPGVIPTDEAAAEAVALDPDVLED
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHC
PVEPALGVIERVVREYPGALSDKFGIDESMDPERILRDISERLGKDLRTTAKLLLREWVD
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
GSLVEIYRTTRADLAETSELEVGGTAQRLVEETLREIEEVVPEGIPPSAATVRGILTRLA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HGENVDGVGFGTIRLGEYGVGVSVGDRYYDRMVRRLRRELGGEVISEERFRVGANGRKAV
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHEECCCCCEEE
ALVTKGR
EEEECCC
>Mature Secondary Structure 
PPKWYRHVMRVLSESHVVLEVRDVRYPEETRWEKLPRLEDVFDFTRVVVLNKADLVPRA
CCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCH
ETERVKEEVELEEDVPAVYVSARERMGFRHLRRTIYEVAPEDVETVRVGVVGFQNVGKST
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHH
IINALTRRSAAETSRRAGYTRGKQWVRGGRKLLVIDSPGVIPTDEAAAEAVALDPDVLED
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCHHHHHC
PVEPALGVIERVVREYPGALSDKFGIDESMDPERILRDISERLGKDLRTTAKLLLREWVD
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
GSLVEIYRTTRADLAETSELEVGGTAQRLVEETLREIEEVVPEGIPPSAATVRGILTRLA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HGENVDGVGFGTIRLGEYGVGVSVGDRYYDRMVRRLRRELGGEVISEERFRVGANGRKAV
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHEECCCCCEEE
ALVTKGR
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]