| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is dnaC [H]
Identifier: 19747016
GI number: 19747016
Start: 1856780
End: 1858141
Strand: Reverse
Name: dnaC [H]
Synonym: spyM18_2217
Alternate gene names: 19747016
Gene position: 1858141-1856780 (Counterclockwise)
Preceding gene: 19747017
Following gene: 19747015
Centisome position: 98.05
GC content: 39.13
Gene sequence:
>1362_bases TTGCCTGAAGTAGCTGAATTACGAGTTCAACCCCAAGATTTACTAGCAGAGCAATCTGTTCTTGGGTCAATCTTTATCTC ACCTGATAAGCTGATTGCAGTGAGAGAATTTATCAGTCCAGACGATTTTTATAAGTACGCTCATAAAATTATCTTTCGGG CAATGATTACTCTCAGCGATCGTAATGATGCCATTGATGCAACCACTATAAGAACAATCCTAGATGATCAAGATGATCTG CAAAGTATTGGTGGCTTATCCTATATTGTTGAACTAGTTAATAGTGTCCCAACTAGCGCTAATGCAGAATATTATGCTAA AATTGTAGCTGAGAAAGCTATGTTGCGTGATATTATTGCTAGGTTGACAGAATCTGTCAACCTAGCTTATGATGAAATTT TAAAACCAGAAGAGGTTATCGCTGGAGTTGAGAGAGCTTTAATTGAACTCAATGAACATAGTAATCATAGTGGGTTTCGC AAAATTTCAGATGTGCTAAAAGTTAATTACGAGGCTTTAGAAGCACGTTCTAAGCAGACTTCAAATGTTACAGGTTTACC AACTGGTTTTAGAGACCTTGACAAGATTACAACAGGTTTACACCCAGATCAATTAGTTATTTTAGCTGCTCGGCCAGCAG TGGGGAAGACTGCCTTTGTTCTTAATATTGCGCAAAATGTGGGGACTAAGCAAAAAAAGACTGTTGCTATTTTTTCTTTG GAAATGGGTGCTGAAAGTTTAGTAGATCGCATGCTTGCAGCAGAAGGAATGGTTGATTCGCACAGTTTAAGAACAGGGCA ACTCACAGATCAGGACTGGAATAATGTAACAATTGCTCAGGGAGCTTTGGCAGAAGCACCGATTTATATTGATGATACGC CCGGGATTAAAATTACTGAAATCCGCGCAAGATCACGGAAATTGTCTCAAGAAGTGGATGGTGGTTTAGGTCTCATTGTA ATTGACTACTTACAGTTGATTACAGGAACTAAACCCGAAAATCGTCAGCAAGAGGTTTCAGATATTTCAAGACAGCTTAA AATCCTAGCTAAAGAATTGAAAGTACCAGTTATTGCCCTAAGCCAGCTTTCTCGTGGCGTTGAGCAAAGGCAAGATAAAC GACCAGTTTTATCAGATATTCGTGAATCAGGATCTATTGAGCAGGATGCCGATATTGTAGCCTTCTTATACCGGGACGAT TATTACCGTAAAGAAGGTGATGATGCTGAAGAAGCTGTTGAAGATAACACAATTGAAGTTATCCTCGAGAAAAATAGAGC TGGGGCGCGTGGAACAGTCAAACTGATGTTCCAAAAAGAATACAACAAATTCTCAAGTATAGCCCAGTTTGAAGAAAGAT AA
Upstream 100 bases:
>100_bases AAGTTCCTGTGAAATTACATAAGGAACTAACAGCTGAGATTAAATTGGCTATCACAGAAGCATAATATAAAAAACATCAC AAGATTTGGAGGTTATGAGG
Downstream 100 bases:
>100_bases GAAAGAGAGACAAAAAATGAGCGATGCATTTACAGATGTTGCAAAAATGAAAAAAATTAAAGAGGACATAAGAGCCCATG AAGGACAGTTAGTAGAATTA
Product: replicative DNA helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 453; Mature: 452
Protein sequence:
>453_residues MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDL QSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNHSGFR KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSL EMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIV IDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDD YYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER
Sequences:
>Translated_453_residues MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDL QSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNHSGFR KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSL EMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIV IDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDD YYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER >Mature_452_residues PEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQ SIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNHSGFRK ISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSLE MGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVI DYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDY YRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER
Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.
COG id: COG0305
COG function: function code L; Replicative DNA helicase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 SF4 helicase domain [H]
Homologues:
Organism=Escherichia coli, GI1790486, Length=453, Percent_Identity=42.6048565121413, Blast_Score=342, Evalue=4e-95,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR007692 - InterPro: IPR007694 - InterPro: IPR007693 - InterPro: IPR016136 [H]
Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 50451; Mature: 50320
Theoretical pI: Translated: 4.67; Mature: 4.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSD CCCHHHHCCCHHHHHHHHHHHHHEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC RNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIA CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH RLTESVNLAYDEILKPEEVIAGVERALIELNEHSNHSGFRKISDVLKVNYEALEARSKQT HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC SNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSL CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHEEEEHHHCCCCCCCEEEEEEE EMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITE CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCEEEEH IRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIAL HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH SQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGDDAEEAVEDNTIEV HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHCCCCCCHHHHHCCCCEEE ILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER EEECCCCCCCCEEEEEEHHHHHHHHHHHHHHCC >Mature Secondary Structure PEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFYKYAHKIIFRAMITLSD CCHHHHCCCHHHHHHHHHHHHHEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC RNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANAEYYAKIVAEKAMLRDIIA CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH RLTESVNLAYDEILKPEEVIAGVERALIELNEHSNHSGFRKISDVLKVNYEALEARSKQT HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC SNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTAFVLNIAQNVGTKQKKTVAIFSL CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHEEEEHHHCCCCCCCEEEEEEE EMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITE CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCEEEEH IRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIAL HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH SQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGDDAEEAVEDNTIEV HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHCCCCCCHHHHHCCCCEEE ILEKNRAGARGTVKLMFQKEYNKFSSIAQFEER EEECCCCCCCCEEEEEEHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7584024; 9384377; 1312531 [H]