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The map label for this gene is emm18 [H]

Identifier: 19746911

GI number: 19746911

Start: 1739482

End: 1740684

Strand: Reverse

Name: emm18 [H]

Synonym: spyM18_2076

Alternate gene names: 19746911

Gene position: 1740684-1739482 (Counterclockwise)

Preceding gene: 19746912

Following gene: 19746910

Centisome position: 91.86

GC content: 36.91

Gene sequence:

>1203_bases
ATGGTTAGAAAAGATGCAAATAGACAGTATTCGCTTAGAAAATTAAAAAAAAGTACTGCTTCAGTAGCGGTTGCTTTGAG
TGCCTTAGGGGTAGGATTAGCGGTTAACCAAACAGAAGTTAGCGCAGCACCTCTTACTCGAGCTACAGCAGACAATAAAG
ACGAATTAATAAAAAGAGCTAACGGTTATGAGATACAGAACCATCAGTTAACAGTTGAGAATAAAAAATTAAAAATTGAT
AAGGAACAGTTAACAAAAGAGAATGATGATTTAAAAACTGAGAAGGATCAGTTAGAACAACGGAGTGAGAAGTTAGCTAC
TCAGAAAGAAAATCTTGAAAAAGAAGTAGCGGAAGCGAAACACAAGAATGAAACGTTAAACATTAATAATGATGACTTAA
CTAAAAAGTTGAATGAAACTCGACAAGAATTAGCAAATAAACAGCAAGAGAGTAAAGAAAATGAAAAGACCCTTAATGAA
CTCTTGGAAAAGACAGTAAAAGATAAAATTGCGAGAGAGCAAAAAAGTAAACAAGACTTTGGTGCCCTTAAACAAGAATT
GGCTAAAAAAGAAGAACAAAACAAAATTTCAGAAGCAAGTCGTAAAGGTCTTCGTCGTGACTTAGATGCATCACGTGAAG
CTAAGAAACAAGTTGAAAAAGATTTAGCAAACTTGACTGCTGAACTTGATAAGGTTAAAGAAGAAAAACAAATCTCAGAC
GCAAGCCGTCAAGGTCTTCGCCGTGACTTGGACGCATCACGTGAAGCTAAGAAACAAGTTGAAAAAGCTTTAGAAGAAGC
AAACAGCAAATTAGCTGCTCTTGAAAAACTTAACAAAGAGCTTGAAGAAAGCAAGAAATTAACAGAAAAAGAAAAAGCTG
AGCTACAAGCAAAACTTGAAGCAGAAGCAAAAGCACTCAAAGAACAATTAGCAAAACAAGCTGAAGAACTTGCAAAACTA
AGAGCTGAAAAAGCATCAGACTCACAAACCCCTGATGCAAAACCAGGAAACAAAGCTGTTCCAGGTAAAGGTCAAGCACC
ACAAGCAGGTACAAAACCTAACCAAAACAAAGCACCAATGAAGGAAACTAAGAGACAGTTACCATCAACAGGTGAAGCAG
CCAACCCATTCTTTACAGCAGCAGCTGCAACAGTGATGGTATCTGCGGGTATGCTTGCTCTAAAACGCAAAGAAGAAAAC
TAA

Upstream 100 bases:

>100_bases
CCTTTTACCGCTTATTCTTTAGAATAGAATTATTAGAGAGAAGTCTTAGAAAAATGAGGCTAATTCCCTAAAGATGAAAA
AGTAAAATAAGGAGCAAATA

Downstream 100 bases:

>100_bases
GCCTTTAGAACTTGGTTTTTGTAACGGTGCAATAGACAAAAGCAAGCAAGGCCAAAAACTGAGAAAATCCTAAAAAGCAG
GCCTTTACCCCTCAAGATTA

Product: M18 protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRANGYEIQNHQLTVENKKLKID
KEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAKHKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNE
LLEKTVKDKIAREQKSKQDFGALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD
ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKL
RAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN

Sequences:

>Translated_400_residues
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRANGYEIQNHQLTVENKKLKID
KEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAKHKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNE
LLEKTVKDKIAREQKSKQDFGALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD
ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKL
RAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
>Mature_400_residues
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRANGYEIQNHQLTVENKKLKID
KEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAKHKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNE
LLEKTVKDKIAREQKSKQDFGALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD
ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKL
RAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN

Specific function: This protein is one of the different antigenic serotypes of protein M. Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the M protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019950
- InterPro:   IPR019931
- InterPro:   IPR003345
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00746 Gram_pos_anchor; PF02370 M; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 44646; Mature: 44646

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHCCHHHCCCCHHHHHHHC
NGYEIQNHQLTVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAK
CCCEECCCEEEEECCCEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNELLEKTVKDKIAREQKSKQDF
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKALKEQLAKQAEELAKLRAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
KETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHCCHHHCCCCHHHHHHHC
NGYEIQNHQLTVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAK
CCCEECCCEEEEECCCEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKNETLNINNDDLTKKLNETRQELANKQQESKENEKTLNELLEKTVKDKIAREQKSKQDF
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALKQELAKKEEQNKISEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKALKEQLAKQAEELAKLRAEKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
KETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3281944; 7891551; 6368549 [H]