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The map label for this gene is adcA [H]

Identifier: 19746909

GI number: 19746909

Start: 1734523

End: 1735443

Strand: Reverse

Name: adcA [H]

Synonym: spyM18_2073

Alternate gene names: 19746909

Gene position: 1735443-1734523 (Counterclockwise)

Preceding gene: 19746910

Following gene: 19746908

Centisome position: 91.58

GC content: 40.07

Gene sequence:

>921_bases
ATGAAAAAAGGTTTTTTTCTCATGGTTATGGTCGTGAGTTTAGTAATGATAGCAGGGTGTGATAAGTCAGCAAACCCCAA
ACAGCCTACGCAAGGCATGTCAGTTGTAACCAGCTTTTACCCAATGTATGCGATGACAAAAGAAGTATCTGGAGACCTAA
ATGATGTGAGGATGATCCAATCAGGTGCAGGCATTCATTCCTTTGAACCGTCTGTAAATGATGTAGCAGCTATTTATGAC
GCGGATTTGTTTGTTTACCATTCACATACCTTAGAAGCTTGGGCAAGGGATCTAGACCCTAATTTAAAAAAATCAAAGGT
TGATGTGTTTGAAGCGTCAAAACCTTTGACACTAGATAGAGTCAAAGGGCTAGAAGATATGGAAGTCACACAAGGCATTG
ACCCTGCGACACTTTATGACCCACATACCTGGACGGATCCCGTTTTAGCTGGTGAAGAAGCTGTTAATATCGCTAAAGAG
CTAGGACGTTTGGATCCTAAACACAAAGACAGTTACACTAAAAATGCTAAGGCTTTCAAAAAAGAAGCAGAGCAACTAAC
TGAAGAATACACTCAAAAATTTAAAAAGGTGCGCTCAAAAACATTCGTGACGCAACACACGGCATTTTCTTATCTGGCTA
AACGATTCGGCTTGAAACAACTTGGTATCTCGGGTATTTCTCCAGAGCAAGAGCCCTCTCCTCGCCAATTGAAAGAAATT
CAAGACTTTGTCAAAGAATACAACGTCAAGACTATTTTTGCAGAAGACAATGTCAATCCCAAAATTGCTCATGCTATTGC
GAAATCAACAGGAGCTAAAGTAAAGACATTAAGTCCACTTGAAGCTGCTCCAAGCGGAAACAAGACATATCTAGAAAATC
TTAGAGCAAATTTGGAAGTGCTCTATCAACAGTTGAAGTAA

Upstream 100 bases:

>100_bases
CATACAGTGATAAAAGATGGTAATTGCCATTGACAAAGCATTGATAAAGGAGTAAAATTAACTGGTTAATAACTGGTTAA
ATTATAATTGAGGAGGTACT

Downstream 100 bases:

>100_bases
AGGAGATTATTAGTGAAGAAAACATATGGTTATATCGGCTCAGTTGCTGCCATTTTACTAGCTACTCATATTGGAAGTTA
CCAGCTTGGTAAGCATCATA

Product: laminin adhesion

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYD
ADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEI
QDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK

Sequences:

>Translated_306_residues
MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYD
ADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEI
QDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>Mature_306_residues
MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYD
ADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
LGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEI
QDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=255, Percent_Identity=25.0980392156863, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34182; Mature: 34182

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDR
CCCCCCCCCCCHHHHHHHHHCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
VKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFK
HCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHH
QDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEV
HHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCHHCCCCCCHHHHHHHHHHHHH
LYQQLK
HHHHHC
>Mature Secondary Structure
MKKGFFLMVMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDR
CCCCCCCCCCCHHHHHHHHHCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
VKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFK
HCCCCHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHH
QDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEV
HHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCHHCCCCCCHHHHHHHHHHHHH
LYQQLK
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]