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The map label for this gene is cysS [H]

Identifier: 19746854

GI number: 19746854

Start: 1670837

End: 1672180

Strand: Reverse

Name: cysS [H]

Synonym: spyM18_2008

Alternate gene names: 19746854

Gene position: 1672180-1670837 (Counterclockwise)

Preceding gene: 19746855

Following gene: 19746853

Centisome position: 88.24

GC content: 41.15

Gene sequence:

>1344_bases
ATGATTAAAATTTATGATACCATGACCCGTTCGCTCCGCAAGTTTGTACCTTTGACTGAAAATACAGTCAATATGTACGT
TTGTGGACCGACGGTCTATAATTATATTCATATTGGAAATGCTAGATCAGCGGTCGCTTTTGACACCATTCGACGTTATT
TTGAGTATACTGGCTATCAGGTCAATTACATTTCCAATTTTACCGATGTCGATGATAAAATTATCAAGGCTGCTACTCAA
GCAGGTGTTTCTCCTAAAGAATTGTCAGATCGCTTTATTGCAGCTTTTATAGAAGATACCAAGGCACTTGGTGTTAAGCC
AGCCACACAAAATCCTCGTGTTATGGATTATATAGCAGAAATCATTTCATTTGTTGAAAGTCTCATTGAAAAAGATTTTG
CTTACGAAGCAGATGGAGATGTGTATTTCCGCGTGGAAAAGTCAGAGCATTATGCCAAGCTAGCTAATAAAACCCTGTCA
GAACTTGAAGTTGGAGCCAGTGGTCGAACAGATGCTGAGACAGCTTTAAAAGAAAATCCACTGGACTTTGCTCTTTGGAA
ATCAGCTAAGGCAGGTGAGGTTTCTTGGGATAGCCCCTGGGGGTTTGGTCGTCCAGGCTGGCACATTGAATGTTCTGTGA
TGGCTACTGAAATTCTTGGTGATACCATTGATATTCATGGTGGCGGAGCTGATTTGGAATTTCCTCATCATACCAATGAA
ATTGCCCAATCTGAGGCCAAAACAGGCAAGACTTTTGCTAACTATTGGATGCACAATGGGTTTGTCACTGTTGATAACGA
AAAAATGTCCAAGTCACTAGGTAATTTTGTGACCGTTCATGAGATGTTACAAACCGTTGATGGTCAGGTTTTGCGATTCT
TTCTTGCGACACAACAGTACCGAAAACCAATTAACTTCACTGAAAAGGCTATTCATGATGCGGAAATCAATCTGAAGTAT
CTTAAAAACACCTTGCAACAACCGCTGACAGAAACTGCAGATGAGCAAGAGCTAAAACAGTTTGTAATAGCTTTCCAAGA
CGCTATGGACGATGATTTCAATACAGCAAATGGGATTACCGTCGTATTTGACATGGCCAAGTGGATTAATTCTGGCTCTT
ATACAGAACCTGTTAAAAGCGCTTTTGAGAAAATGTTAGCTGTTTTTGGCATTATCTTTGAAGAAGAGGTGCTTGAGGTT
GACATTGAAGCCTTGATTGCTAAGCGACAAGAAGCACGCGCGAATCGTGATTTTGCCACAGCTGATGCCATTCGAGATCA
GTTAGCAGCTCAAGGCATCAAGCTGCTAGATACCAAAGATGGTGTGAGGTGGCTGCGTGACTAA

Upstream 100 bases:

>100_bases
TATTAATATTAAATTGTTGAAAAGGTGGAATAGCATTTCAGAAAAAGACTTAGGATATCAAGATGACAACTAATGCTAGG
ATATTGAATAAGGAGTTTAC

Downstream 100 bases:

>100_bases
TCCAGTTGATGTGAATTTGATTAATGGTATTGCTCTAGCCTTTGAAGGGGATGCGGTTTATTCCTACTATGTTCGTCGTC
ATCTCATTTTTCAAGGTAAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSAVAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQ
AGVSPKELSDRFIAAFIEDTKALGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNE
IAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNFVTVHEMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKY
LKNTLQQPLTETADEQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGIIFEEEVLEV
DIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD

Sequences:

>Translated_447_residues
MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSAVAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQ
AGVSPKELSDRFIAAFIEDTKALGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNE
IAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNFVTVHEMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKY
LKNTLQQPLTETADEQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGIIFEEEVLEV
DIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD
>Mature_447_residues
MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSAVAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQ
AGVSPKELSDRFIAAFIEDTKALGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNE
IAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNFVTVHEMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKY
LKNTLQQPLTETADEQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGIIFEEEVLEV
DIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=487, Percent_Identity=34.9075975359343, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI303304987, Length=348, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI62240992, Length=348, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI21269877, Length=348, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI10835051, Length=348, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786737, Length=466, Percent_Identity=44.6351931330472, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17509795, Length=246, Percent_Identity=39.0243902439024, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17509797, Length=246, Percent_Identity=39.0243902439024, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=231, Percent_Identity=45.4545454545455, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19922218, Length=507, Percent_Identity=33.1360946745562, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI19922364, Length=237, Percent_Identity=42.1940928270042, Blast_Score=191, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 50465; Mature: 50465

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSAVAFDTIRRYFEYTGYQ
CEEEHHHHHHHHHHHCCCCCCCEEEEEECHHHEEEEEECCCCCHHHHHHHHHHHHHCCEE
VNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKALGVKPATQNPRVMDYIAE
EEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLSELEVGASGRTDAETALKENP
HHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
LDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNE
CCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEEECCCCCCCCCCCCHHH
IAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNFVTVHEMLQTVDGQVLRFFLATQQY
HHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPINFTEKAIHDAEINLKYLKNTLQQPLTETADEQELKQFVIAFQDAMDDDFNTANGIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VVFDMAKWINSGSYTEPVKSAFEKMLAVFGIIFEEEVLEVDIEALIAKRQEARANRDFAT
EEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ADAIRDQLAAQGIKLLDTKDGVRWLRD
HHHHHHHHHHCCCEEEECCCCHHHHCC
>Mature Secondary Structure
MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSAVAFDTIRRYFEYTGYQ
CEEEHHHHHHHHHHHCCCCCCCEEEEEECHHHEEEEEECCCCCHHHHHHHHHHHHHCCEE
VNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKALGVKPATQNPRVMDYIAE
EEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLSELEVGASGRTDAETALKENP
HHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
LDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNE
CCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCEEECCCCCCCCCCCCHHH
IAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNFVTVHEMLQTVDGQVLRFFLATQQY
HHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKPINFTEKAIHDAEINLKYLKNTLQQPLTETADEQELKQFVIAFQDAMDDDFNTANGIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCE
VVFDMAKWINSGSYTEPVKSAFEKMLAVFGIIFEEEVLEVDIEALIAKRQEARANRDFAT
EEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ADAIRDQLAAQGIKLLDTKDGVRWLRD
HHHHHHHHHHCCCEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]