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The map label for this gene is recG [H]

Identifier: 19746733

GI number: 19746733

Start: 1531566

End: 1533581

Strand: Reverse

Name: recG [H]

Synonym: spyM18_1857

Alternate gene names: 19746733

Gene position: 1533581-1531566 (Counterclockwise)

Preceding gene: 19746734

Following gene: 19746732

Centisome position: 80.93

GC content: 37.1

Gene sequence:

>2016_bases
ATGATATTAACAGCTCCTATGTCCAACTTAAAGGGATTTGGACCAAAATCAGCAGAAAAATTTCAGAAATTAGATATTTA
TACAGTAGAAGATTTACTGCTTTATTATCCGTTTCGCTATGAAGATTTTAAATCAAAATCTGTTTTTGATTTAGTGGATG
GTGAAAAAGCAGTCATTACAGGCTTAGTCGTTACTCCAGCTAATGTACAATATTATGGTTTTAAACGTAACCGTTTAAGT
TTCAAATTGCGTCAAGGGGAAGCTGTCTTAAATGTTAGTTTTTTTAATCAACCCTATTTAGCTGATAAAATAGAACTTGG
TCAAGAGGTAGCTGTTTTTGGTAAATGGGATGCTACTAAATCGGCTATTACTGGGATGAAGGTTTTAGCTCAAGTTGAAG
ATGACATGCAACCTGTTTATCGCGTAGCTCAGGGAATTTCACAGTCTACTTTGATTAAAGCTATTAAGTCAGCTTTTGAA
ATCGATGCGCATTTGGAATTGAAGGAAAATTTACCAGCTACTTTATTGGAAAAATACCGATTGATGGGTCGTAGTCAGGC
TTGTTTAGCTATGCATTTCCCAAAAGATATCACAGAGTATAAGCAAGCGCTCCGTCGGATTAAATTTGAAGAATTATTTT
ACTTTCAAATGAACCTTCAAGTTTTGAAAGCCGAAAATAGATCTGAAACAAATGGTTTGCCTATTCTTTATAGTAAACAT
GCTATGGAGACAAAGATTTCCTCTTTACCTTTTATTCTAACGAATGCTCAAAAGCGCTCTTTAGATGACATATTATCTGA
TATGTCATCGGGAGCTCATATGAATCGTTTATTGCAAGGAGATGTAGGATCAGGAAAGACAGTCATTGCTGGTCTATCAA
TGTATGCAGCTTATACAGCAGGTTTTCAATCGGCTTTGATGGTTCCAACGGAAATCCTAGCTGAACAACACTATATTAGT
CTGCAAGAGTTATTTCCAGATTTATCAATTGCTATATTAACTTCGGGTATGAAAGCCGCTGTCAAGCGTACGGTTTTAGC
AGCTATTGCAAATGGCTCGGTTGATATGATTGTAGGAACTCATGCTCTTATCCAAGACTCGGTACAGTACCATAAACTGG
GGCTTGTCATTACAGACGAGCAACATCGTTTTGGTGTTAAACAGCGTAGAATTTTCCGTGAAAAGGGAGAAAATCCTGAT
GTTTTAATGATGACAGCCACCCCAATTCCCCGAACCCTAGCAATCACAGCTTTTGGAGAAATGGATGTTTCTGTTATTGA
TGAATTACCTGCCGGTCGTAAACCTATTATGACACGCTGGGTGAAACACGAGCAGCTAGGGACTGTGTTGGAATGGGTAA
AAGGTGAATTGCAAAAAGATGCTCAAGTGTATGTCATTTCACCGTTGATTGAAGAATCAGAAGCTTTAGATTTAAAGAAT
GCAGTAGCATTGCATGCTGAATTATCTACTTATTTTGAAGGAATTGCTAAGGTTGCTCTTGTACATGGACGTATGAAAAA
TGATGAAAAAGATGCTATAATGCAAGATTTCAAGGATAAAAAAAGTCATATTTTAGTATCCACAACAGTTATTGAAGTAG
GGGTAAATGTCCCAAATGCAACGATCATGATTATTATGGATGCCGATCGTTTTGGATTAAGTCAGTTACATCAACTTCGT
GGGCGTGTTGGTCGTGGACATAAACAATCATACGCTGTTTTAGTGGCTAATCCCAAAACGGATTCGGGGAAAAAACGAAT
GACAATCATGACAGAAACGACAGATGGTTTCGTTTTGGCTGAGTCGGATTTAAAAATGCGTGGTTCTGGCGAAATCTTTG
GTACTCGTCAGTCTGGAATTCCAGAATTTCAAGTAGCTGATATCGTTGAGGATTATCCTATTTTAGAAGAAGCACGCAAA
GTTTCTGCAGCGATTGTTTCTGATCCTAACTGGATATATGAAAAACAGTGGCAATTAGTAGCAAAAAATATTAGAAAAAA
AGAAGTTTATGATTAA

Upstream 100 bases:

>100_bases
AATTCCAAAGAACGTCGCTGCCGTAAGCACCACCTAAGGAAAGTATCACGACAAACTTTGTCTTCAATCTGACAAGAGTT
TTTGTGAAGGGAAAAAGATA

Downstream 100 bases:

>100_bases
CTTAAAACAAGTCGTTGTTTTACAAATATTTAGTTAGTTTTGAGATAAACTGTTATAAAGTATAAAGAGGTCACTATTTC
TGGCCTTTTTTACTTATGCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLS
FKLRQGEAVLNVSFFNQPYLADKIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKH
AMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYIS
LQELFPDLSIAILTSGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPD
VLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVLEWVKGELQKDAQVYVISPLIEESEALDLKN
AVALHAELSTYFEGIAKVALVHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLR
GRVGRGHKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARK
VSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD

Sequences:

>Translated_671_residues
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLS
FKLRQGEAVLNVSFFNQPYLADKIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKH
AMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYIS
LQELFPDLSIAILTSGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPD
VLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVLEWVKGELQKDAQVYVISPLIEESEALDLKN
AVALHAELSTYFEGIAKVALVHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLR
GRVGRGHKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARK
VSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD
>Mature_671_residues
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLS
FKLRQGEAVLNVSFFNQPYLADKIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKH
AMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYIS
LQELFPDLSIAILTSGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPD
VLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVLEWVKGELQKDAQVYVISPLIEESEALDLKN
AVALHAELSTYFEGIAKVALVHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLR
GRVGRGHKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARK
VSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=666, Percent_Identity=38.2882882882883, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI1787357, Length=402, Percent_Identity=38.0597014925373, Blast_Score=268, Evalue=9e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75180; Mature: 75180

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFDLVDGEKAVIT
CEEECCCHHCCCCCCCCHHHHHHCCEEEEHHHHHCCCCCCCCCCCCCEEECCCCCEEEEE
GLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLADKIELGQEVAVFGKWDATK
EEEEECCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCHHHHHCCCEEEEEECCCCHH
SAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFEIDAHLELKENLPATLLEKYR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
LMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKH
HCCCCCCEEEEECCHHHHHHHHHHHHCCHHHEEEEEEEEEEEECCCCCCCCCCCEEEECH
AMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTA
HHHHHHCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
GFQSALMVPTEILAEQHYISLQELFPDLSIAILTSGMKAAVKRTVLAAIANGSVDMIVGT
CCHHHHHCHHHHHHHHHCEEHHHHCCCCEEEHHHCCHHHHHHHHHHHHHCCCCEEEEECC
HALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPDVLMMTATPIPRTLAITAFGE
HHHHHHCHHEEEEEEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSVIDELPAGRKPIMTRWVKHEQLGTVLEWVKGELQKDAQVYVISPLIEESEALDLKN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHCCCHHCCHHH
AVALHAELSTYFEGIAKVALVHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCE
TIMIIMDADRFGLSQLHQLRGRVGRGHKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLA
EEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEE
ESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLV
ECCCEECCCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHEEECCCCHHHHHHHHHH
AKNIRKKEVYD
HHHHHHHCCCC
>Mature Secondary Structure
MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFKSKSVFDLVDGEKAVIT
CEEECCCHHCCCCCCCCHHHHHHCCEEEEHHHHHCCCCCCCCCCCCCEEECCCCCEEEEE
GLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLADKIELGQEVAVFGKWDATK
EEEEECCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCHHHHHCCCEEEEEECCCCHH
SAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFEIDAHLELKENLPATLLEKYR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
LMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMNLQVLKAENRSETNGLPILYSKH
HCCCCCCEEEEECCHHHHHHHHHHHHCCHHHEEEEEEEEEEEECCCCCCCCCCCEEEECH
AMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNRLLQGDVGSGKTVIAGLSMYAAYTA
HHHHHHCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
GFQSALMVPTEILAEQHYISLQELFPDLSIAILTSGMKAAVKRTVLAAIANGSVDMIVGT
CCHHHHHCHHHHHHHHHCEEHHHHCCCCEEEHHHCCHHHHHHHHHHHHHCCCCEEEEECC
HALIQDSVQYHKLGLVITDEQHRFGVKQRRIFREKGENPDVLMMTATPIPRTLAITAFGE
HHHHHHCHHEEEEEEEEECCHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSVIDELPAGRKPIMTRWVKHEQLGTVLEWVKGELQKDAQVYVISPLIEESEALDLKN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHCCCHHCCHHH
AVALHAELSTYFEGIAKVALVHGRMKNDEKDAIMQDFKDKKSHILVSTTVIEVGVNVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCE
TIMIIMDADRFGLSQLHQLRGRVGRGHKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLA
EEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEE
ESDLKMRGSGEIFGTRQSGIPEFQVADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLV
ECCCEECCCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHEEECCCCHHHHHHHHHH
AKNIRKKEVYD
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]