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The map label for this gene is brpA [H]

Identifier: 19746634

GI number: 19746634

Start: 1447639

End: 1448922

Strand: Reverse

Name: brpA [H]

Synonym: spyM18_1741

Alternate gene names: 19746634

Gene position: 1448922-1447639 (Counterclockwise)

Preceding gene: 19746635

Following gene: 19746631

Centisome position: 76.46

GC content: 38.24

Gene sequence:

>1284_bases
ATGAAAATTGGAAAAAAAATAGTTTTAATGTTCACAGCTATTGTGTTAACAACTGTCTTGGCATTAGGTGTCTATCTAAC
TAGTGCTTATACCTTCTCAACAGGAGAATTATCAAAGACCTTTAAAGATTTTTCGACATCTTCAAAGAAAAGTGATGCCA
TTAAACAAACAAGAGCTTTTTCTATCTTGTTGATGGGTGTTGATACAGGCTCTTCAGAGCGTGCCTCCAAGTGGGAAGGA
AACAGTGATTCGATGATTTTGGTTACGGTTAATCCAAAGACCAAGAAAACAACTATGACTAGTTTAGAACGAGATACCTT
AACCACGTTATCTGGACCCAAAAATAATGAAATGAATGGTGTTGAAGCTAAGCTTAACGCTGCTTATGCAGCAGGTGGCG
CTCAGATGGCTATTATGACCGTGCAAGATCTTTTGAATATCACCATTGATAACTATGTTCAAATTAATATGCAAGGCCTT
ATTGATCTTGTGAATGCAGTTGGAGGGATTACAGTTACAAATGAGTTTGATTTTCCTATCTCGATTGCTGAAAACGAACC
TGAATATCAAGCTACTGTTGCGCCTGGAACACACAAAATTAACGGTGAACAAGCTTTGGTTTATGCTCGTATGCGTTATG
ATGATCCTGAGGGAGATTATGGTCGACAAAAGCGTCAACGTGAAGTCATTCAAAAGGTATTGAAAAAAATCCTTGCTCTT
GATAGCATTAGCTCTTATCGGAAGATTTTATCTGCTGTAAGTAGTAATATGCAAACGAATATCGAAATCTCTTCTCGCAC
TATCCCTAGTCTATTAGGTTATCGTGACGCACTTAGAACTATTAAGACTTATCAACTAAAAGGAGAAGATGCCACTTTAT
CAGATGGTGGATCATACCAAATTGTTACCTCTAATCATTTGTTAGAAATCCAAAATCGTATCCGAACAGAATTAGGACTT
CATAAGGTTAGTCAATTAAAAACAAATGCTACTGTTTATGAAAATTTGTATGGGTCAACTAAGTCTCAGACAGTAAACAA
CAACTATGACTCTTCAGGCCAGGCTCCATCTTATTCTGATAGTCATAGCTCTTACGCTAATTATTCAAGTGGAGTAGATA
CCGGCTCATCTTATCAGAGTGCTAGTACAGACCAGGACTCTACTGCTTCAAGCCATACGCCAACTACGCCGTCTTCTTCA
TCAGATGCTTTAGCAGCTGATGAGTCTAGCTCATCAGGGTCTGGATCATTAGTTCCTCCTGCTAATATCAACCCTCAGAC
CTAA

Upstream 100 bases:

>100_bases
TTCGTATTGAAAGTATGCGAAAAAACGACATCAAATCAAAAAATGGAGATGACTTAGATGTTTATCATATGCGTAAATCT
GTAAGTCAGTAAGTGAATCG

Downstream 100 bases:

>100_bases
CGTTCTGAGGATTTTTATGTTTAAAATATCCGATTTTGAATATAAAAAAGACAGGTATCAAAGATGATAGCTGTCTGTGA
TTTCAAATAAAGTATATGAG

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEG
NSDSMILVTVNPKTKKTTMTSLERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
DSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGL
HKVSQLKTNATVYENLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSS
SDALAADESSSSGSGSLVPPANINPQT

Sequences:

>Translated_427_residues
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEG
NSDSMILVTVNPKTKKTTMTSLERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
DSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGL
HKVSQLKTNATVYENLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSS
SDALAADESSSSGSGSLVPPANINPQT
>Mature_427_residues
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEG
NSDSMILVTVNPKTKKTTMTSLERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
DSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGL
HKVSQLKTNATVYENLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSS
SDALAADESSSSGSGSLVPPANINPQT

Specific function: Involved in biofilm formation, cell division, autolysis and the regulation of acid and oxidative stress tolerance. May be associated with systemic virulence in blood [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell envelope (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 46110; Mature: 46110

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKKSDAIKQTRAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHCCCCHHHHHHHHHHEE
SILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSLERDTLTTLSGPKNNEMNG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGLIDLVNAVGGITVTNEFDFPI
HHHHHHHHEECCCCEEHHHHHHHHHHCEECCEEEEEHHHHHHHHHHHCCEEEEECCCCCE
SIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
EECCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQ
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCEECCCCCEE
IVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYENLYGSTKSQTVNNNYDSSGQAPSYSD
EEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSSSDALAADESSSSGSGSLVPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
ANINPQT
CCCCCCC
>Mature Secondary Structure
MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDFSTSSKKSDAIKQTRAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHCCCCHHHHHHHHHHEE
SILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSLERDTLTTLSGPKNNEMNG
EEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGLIDLVNAVGGITVTNEFDFPI
HHHHHHHHEECCCCEEHHHHHHHHHHCEECCEEEEEHHHHHHHHHHHCCEEEEECCCCCE
SIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEGDYGRQKRQREVIQKVLKKILAL
EECCCCCCEEEEECCCCEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRDALRTIKTYQLKGEDATLSDGGSYQ
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCEECCCCCEE
IVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYENLYGSTKSQTVNNNYDSSGQAPSYSD
EEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SHSSYANYSSGVDTGSSYQSASTDQDSTASSHTPTTPSSSSDALAADESSSSGSGSLVPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
ANINPQT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]