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The map label for this gene is mraY [H]

Identifier: 19746580

GI number: 19746580

Start: 1392940

End: 1393950

Strand: Reverse

Name: mraY [H]

Synonym: spyM18_1673

Alternate gene names: 19746580

Gene position: 1393950-1392940 (Counterclockwise)

Preceding gene: 19746581

Following gene: 19746579

Centisome position: 73.56

GC content: 37.88

Gene sequence:

>1011_bases
ATGTTTTTAACCCTTATTGCAGCAATCATATCCTTTATGGTATCTGCTTTCACAATGCCTTATTTTATCAAATTCTATCA
ATTGAAAAAAATTGGTGGGCAACAAATGCATGAAGATGTCAAGCAACATTTAGCTAAAGCTGGAACACCGACTATGGGGG
GAACTGTTTTTCTTTTAGTAGCTACGGCAGTATCGTTATTGGTTAGTCTATTTTCGATCAAAAACACTCAAAGTTTAGCT
TTGATTTCAGGCATTTTATCAATTGTTGTCATTTACGGGATTATCGGATTTTTGGATGATTTTTTAAAAATTTTTAAGCA
AATCAATGAAGGATTGACAGCCAAACAAAAATTAGCCTTGCAGTTGGCTGGAGGATTGATGTTCTATTTTTTACATGTTA
GTCCAAGTGGCATTTCTTCGATCAATGTGTTTGGTTATCAGCTGTCGCTGGGAATTTTCTACCTATTCTTTGTTCTATTC
TGGGTGGTTGGTTTCTCAAATGCCGTTAATTTGACGGATGGTATCGATGGCTTAGCTTCTATCTCAGTGGTGATTAGTTT
AGTGACTTACGGCGTTATTGCCTACGTTCAGTGGCAATTTGATGTCTTATTATTGATTGGAACCATGATTGGTGCTTTAC
TTGGTTTCTTCTGCTTTAACCACAAGCCTGCCAAAGTATTTATGGGAGATGTGGGTAGTTTAGCCCTTGGAGCTATGTTG
GCAGCTATTTCTATTGCGCTTCGTCAAGAATGGACTCTCCTGATTATTGGGATCGTTTATGTTCTTGAAACAAGTTCTGT
GATGTTGCAAGTGTTCTATTTCAAGTACACCAAGAAAAAATATGGAGAAGGTCGTCGTATTTTTAGAATGACGCCTTTCC
ACCACCATTTGGAATTGGGAGGCTTGTCTGGTAAAGGCAAGAAGTGGTCAGAATGGCAGGTAGATGCTTTTTTGTGGGGA
GTAGGAAGTCTAGCTAGTTTACTAGTTTTAGCTATCTTATACGTCTTCTAA

Upstream 100 bases:

>100_bases
TTTAAAGGAACAGATTCTGGTCGTGTTATGAAACAAAGTGTTGATGTTGGTAAGTCCTTGAAAAAAATAAAAAAAATGAC
CATTACTTTAGGAGATTAAC

Downstream 100 bases:

>100_bases
GGGGGATTATCAAGAATAGTCACCAATAGCATTTTGATTAACATCATCAATAAGAGAGTGGAGATGACCCACAAATGCTG
ATTTTGTGAGTGTTGTCCCA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLA
LISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLF
WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQWQFDVLLLIGTMIGALLGFFCFNHKPAKVFMGDVGSLALGAML
AAISIALRQEWTLLIIGIVYVLETSSVMLQVFYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWG
VGSLASLLVLAILYVF

Sequences:

>Translated_336_residues
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLA
LISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLF
WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQWQFDVLLLIGTMIGALLGFFCFNHKPAKVFMGDVGSLALGAML
AAISIALRQEWTLLIIGIVYVLETSSVMLQVFYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWG
VGSLASLLVLAILYVF
>Mature_336_residues
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLA
LISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLF
WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQWQFDVLLLIGTMIGALLGFFCFNHKPAKVFMGDVGSLALGAML
AAISIALRQEWTLLIIGIVYVLETSSVMLQVFYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWG
VGSLASLLVLAILYVF

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=362, Percent_Identity=35.0828729281768, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 37076; Mature: 37076

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLAL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLFWVVGFSNAVNLTDGIDGLAS
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ISVVISLVTYGVIAYVQWQFDVLLLIGTMIGALLGFFCFNHKPAKVFMGDVGSLALGAML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHH
AAISIALRQEWTLLIIGIVYVLETSSVMLQVFYFKYTKKKYGEGRRIFRMTPFHHHLELG
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHEEC
GLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLAL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
QLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLFWVVGFSNAVNLTDGIDGLAS
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ISVVISLVTYGVIAYVQWQFDVLLLIGTMIGALLGFFCFNHKPAKVFMGDVGSLALGAML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHH
AAISIALRQEWTLLIIGIVYVLETSSVMLQVFYFKYTKKKYGEGRRIFRMTPFHHHLELG
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHEEC
GLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]