| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is comFA [H]
Identifier: 19746542
GI number: 19746542
Start: 1351372
End: 1352697
Strand: Reverse
Name: comFA [H]
Synonym: spyM18_1625
Alternate gene names: 19746542
Gene position: 1352697-1351372 (Counterclockwise)
Preceding gene: 19746545
Following gene: 19746541
Centisome position: 71.38
GC content: 35.97
Gene sequence:
>1326_bases ATGGAGTCTATTGAAAATAGTTATGGACGGTTGTTGCTAGAAAGCCAGTTACCAGATTCAGCAAAGCAGCTTGCTCAACC TTTAAAAAGTGTAGTAATATTGAGAGGAAAAATGATTTGTCAACGTTGTCACTATCAGCTTGATGAAGAAGCACGATTGC CAAGTGGAGCCTATTATTGCCGATTTTGTCTTGTCTTTGGACGAAATCAATCAGATAAATTGCTCTATGCTATCCCACCT ATGCATTTTCCAAAAGGTAATTATCTGGTTTGGAGCGGTCAACTAACTGCTTATCAAGAGATAATTTCCCAACAATTATT AATCAATATGCAAAATCAAAAAACAACATTAGTTCATGCTGTAACTGGTTCAGGAAAAACAGAAATGATTTATGCTGCGA TTGAGGCGGTAATTAACACAGGTGGCTGGGTTTGCATTGCCAGCCCAAGAGTAGATGTTTGTGTAGAGGTGGCTACTCGT TTATCCCAAGCCTTCTCCTGCAGCATCTGTTTAATGCACGCAGAGTCTCTTCCTTATCAAAGAGCTCCTATTATAGTAGC CACAACGCATCAGCTGCTAAAATTTCACAAGGCTTTTGATCTCTTAATTATTGATGAAGTAGACGCATTCCCTTTTGTAA ATAATATTCAACTTCATTATGCTGCAAGTCAGGCTTTAAAAGAAGGTGGCGCAAAGATTTTATTAACTGCAACTTCAACT AGAACTTTAGAAAGAAAGGTAAACAAGGGAGAAGTAGTCAAGCTGACATTGGCGAGACGCTTTCATAATAGGCCATTAGT TATTCCAAAATTTATAAGAAGTTTTAATCTATTTAAAATGATACATCGGCAAAAACTTCCTCCTAAAATTTTAAAATACT TAAAAAAACAAAGAAAAACAGGCTATCCCCTTTTAATTTTTCTACCCACTATTATAATGGCAGAATCTGTTACAGCAATC TTAAAAGAGTTATTGCCCGCCGAACAAATAGCTTGTGTTTCTAGTCAATCACAAAACAGGAAAGAAGATATCACAGCTTT TCGTCAAGGAAAAAAAACGATTTTAATTACAACAACAATTTTAGAAAGGGGTGTGACATTTCCCCAAATTGATGTTTTTG TTCTTGGGTCTCATCATCGTGTCTATAGTTCCCAAAGTCTTGTTCAAATTGCTGGACGAGTTGGAAGATCTATAGACAGA CCAGACGGAACGTTATATTTCTTTCATGAAGGTATCAGTAAAGCAATGCTACTAGCAAAAAAAGAGATTAAAGAAATGAA TTATAAAGGGTATTCGCATGATCTGTTTACTATGTCAACAAATTAG
Upstream 100 bases:
>100_bases TTCTTCGAAAAAACCACTGGCTTTGATTGTCTTAAAATGTTCCATAAAAAAATTGTACAAGAAAAGATAAAAATTAGCAA AAAAAAGCGAATAATAAAGT
Downstream 100 bases:
>100_bases TCAAACACCAATAAGTATTACAGAAATCATCTTTTTAAGGCGTATCTCTTCACCGATTTGTCAACAATGTCAAAAAAGCT TTCAAAAGATAGGAAAAAGT
Product: late competence protein
Products: NA
Alternate protein names: ATP-dependent helicase ComFA [H]
Number of amino acids: Translated: 441; Mature: 441
Protein sequence:
>441_residues MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPP MHFPKGNYLVWSGQLTAYQEIISQQLLINMQNQKTTLVHAVTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAI LKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDR PDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLFTMSTN
Sequences:
>Translated_441_residues MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPP MHFPKGNYLVWSGQLTAYQEIISQQLLINMQNQKTTLVHAVTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAI LKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDR PDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLFTMSTN >Mature_441_residues MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPP MHFPKGNYLVWSGQLTAYQEIISQQLLINMQNQKTTLVHAVTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAI LKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDR PDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLFTMSTN
Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]
COG id: COG4098
COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase C-terminal domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014001 - InterPro: IPR001650 - InterPro: IPR014021 - InterPro: IPR006935 [H]
Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 49849; Mature: 49849
Theoretical pI: Translated: 10.00; Mature: 10.00
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYC CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHE RFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEIISQQLLINMQNQKTTLVHA EEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEE VTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATRLSQAFSCSICLMHAESLPYQ EECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEHHCCCCC RAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST CCCEEEECHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCEEEEEECCC RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKT HHHHHHCCCCCEEEEEEHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC GYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTI CCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEHH LERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLAK HHCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH KEIKEMNYKGYSHDLFTMSTN HHHHHCCCCCCCCEEEEEECC >Mature Secondary Structure MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCHYQLDEEARLPSGAYYC CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHE RFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEIISQQLLINMQNQKTTLVHA EEEEEECCCCCCCEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEE VTGSGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATRLSQAFSCSICLMHAESLPYQ EECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEHHCCCCC RAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST CCCEEEECHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCEEEEEECCC RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKT HHHHHHCCCCCEEEEEEHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC GYPLLIFLPTIIMAESVTAILKELLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTI CCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEHH LERGVTFPQIDVFVLGSHHRVYSSQSLVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLAK HHCCCCCCCEEEEEECCCCEECCCHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH KEIKEMNYKGYSHDLFTMSTN HHHHHCCCCCCCCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8412657; 9384377 [H]