Click here to switch to the map view.

The map label for this gene is ygcA [C]

Identifier: 19746533

GI number: 19746533

Start: 1339487

End: 1340842

Strand: Reverse

Name: ygcA [C]

Synonym: spyM18_1615

Alternate gene names: 19746533

Gene position: 1340842-1339487 (Counterclockwise)

Preceding gene: 19746540

Following gene: 19746532

Centisome position: 70.76

GC content: 41.74

Gene sequence:

>1356_bases
ATGGTCGTAAAGGTTAAACAGAAAATTCCTTTAAAAATTAAGCGAATGGGAATTAACGGTGAGGGGATTGGTTTTTATCA
GAAAACTTTGGTATTTGTCCCTGGTGCTTTAAAGGGAGAAGATATTTTTTGCCAAATCACGGCGGTTAAACGGAATTTTG
CAGAGGCCAAACTGTTGATGGTAAACAAGGCTTCTAAGAATCGTGTCAAACCAGCTTGTTCTGTTTATGAAACTTGTGGT
GGTTGCCAAATCATGCATCTAGCCTATCCTAAACAGCTAGATTTCAAAGATGATGTGATTAGGCAGGCCCTTAAAAAGTT
CAAACCAACTGGCTATGAACAATTTGAGATTAGACCGACTTTAGGAATGAAAAAGCCAGATCACTATCGAGCCAAATTGC
AGTTTCAGCTGCGGTCATTTGGCGGGACGGTCAAGGCTGGTTTATTTTCCCAGGGAAGTCATCGCTTGGTTCCTATTGAC
AATTGCTTGGTACAGGATCAACTAACGCAAGATATTATCAATAAGATTACGCAGTTAGTGGACAAGTACAAGTTGCCCAT
TTACAATGAGCGAAAGATTGCTGGGATTCGGACGATAATGGTTCGTAAGGCACAGGCTAGTGATCAGGTACAGATTATTG
TTGTGAGTAGCAAAGAAGTTAGGTTAGCGAGGTTCATTGGCGAATTGACTAAGGCATTTCCTCAGGTTAAAACGGTTGCC
TTGAATAGTAATTGTTCTAAATCGAGTGAGATTTATGGGGACGAAACGGAAATTCTATGGGGACAAGAGGCGATTCATGA
AGAAGTTTTAGACTATGGATTTGCGTTATCACCGAGAACTTTTTACCAACTTAATCCACAGCAGACAGAAGTTTTGTATG
GTGAGGTGGTGAAGGCCTTAGATGTAGGGAGCAAAGATCATATTATTGATGCCTATTGTGGGGTTGGCTCGATTGGCTTT
GCTTTTGCAGGGAAGGTCAAGTCTGTGCGGGGGATGGATATTATCTCAGAAGCGATTGAGGATGCACAAAAAAATGCCAA
AGCCATGGGATTTGACAACGCTTACTATGAGGCAGGGAAGGCAGAGGATATTATTCCTAAATGGTATAAACAAGGTTACC
GCGCGGATGCCATCATTGTGGACCCACCAAGAACTGGTTTAGATGATAAATTATTAAAAACGATTCTTCATTACCAGCCT
AAACAGATGGTTTATGTGTCTTGTAATACCTCCACTTTGGCCCGCGACTTGGTGCAGCTAACAAAGGTTTACGATGTTCA
CTATATCCAAAGTGTAGACATGTTCCCCCATACAGCTAGGACCGAGGCTGTCGTGAAGTTACAAAAACGTGTATGA

Upstream 100 bases:

>100_bases
AAAAATGGTAAAATAGAAGACGAAAATACTGCTAAAAATGTGTTGCTTGTGAATGCTTTTGGTGGTGAGATTAGGATACT
AGAGGAAGTAAGGGGAAGAG

Downstream 100 bases:

>100_bases
TTGAGTGGCAATAACAACTCAAGTTTTATAAGCTCAGGTAATGGGTTTGAGCAATAGCTTGACATAGTAGGGATGTCAAA
AACGGTTTACTAAGCATAGT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFCQITAVKRNFAEAKLLMVNKASKNRVKPACSVYETCG
GCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLARFIGELTKAFPQVKTVA
LNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRTFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGF
AFAGKVKSVRGMDIISEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQP
KQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKRV

Sequences:

>Translated_451_residues
MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFCQITAVKRNFAEAKLLMVNKASKNRVKPACSVYETCG
GCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLARFIGELTKAFPQVKTVA
LNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRTFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGF
AFAGKVKSVRGMDIISEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQP
KQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKRV
>Mature_451_residues
MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFCQITAVKRNFAEAKLLMVNKASKNRVKPACSVYETCG
GCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLARFIGELTKAFPQVKTVA
LNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRTFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGF
AFAGKVKSVRGMDIISEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQP
KQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKRV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=214, Percent_Identity=31.3084112149533, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI51173878, Length=214, Percent_Identity=31.3084112149533, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI269784680, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI269784676, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI20149688, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI269784678, Length=232, Percent_Identity=29.3103448275862, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1789148, Length=452, Percent_Identity=24.7787610619469, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787083, Length=387, Percent_Identity=25.8397932816537, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790403, Length=163, Percent_Identity=31.9018404907975, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=436, Percent_Identity=23.6238532110092, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666579, Length=415, Percent_Identity=27.2289156626506, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 50780; Mature: 50780

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFCQITAVKRNFAEAKLLM
CEEEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEHHCCCCCEEEEE
VNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPT
EECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
LGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPIDNCLVQDQLTQDIINKITQLV
CCCCCCCCCEEEEEEEEHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
DKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLARFIGELTKAFPQVKTVA
HHHCCCCCCCCCHHHHHEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEE
LNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRTFYQLNPQQTEVLYGEVVKAL
ECCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
DVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDIISEAIEDAQKNAKAMGFDNAYYEAGK
CCCCCCCEEEHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHHCCHHCCCCCHHHCCCC
AEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQPKQMVYVSCNTSTLARDLVQL
CCCCCHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
TKVYDVHYIQSVDMFPHTARTEAVVKLQKRV
HHHHHHHHHEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFCQITAVKRNFAEAKLLM
CEEEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEHHCCCCCEEEEE
VNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPT
EECCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEC
LGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPIDNCLVQDQLTQDIINKITQLV
CCCCCCCCCEEEEEEEEHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
DKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLARFIGELTKAFPQVKTVA
HHHCCCCCCCCCHHHHHEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEE
LNSNCSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRTFYQLNPQQTEVLYGEVVKAL
ECCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
DVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDIISEAIEDAQKNAKAMGFDNAYYEAGK
CCCCCCCEEEHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHHCCHHCCCCCHHHCCCC
AEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQPKQMVYVSCNTSTLARDLVQL
CCCCCHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHH
TKVYDVHYIQSVDMFPHTARTEAVVKLQKRV
HHHHHHHHHEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12122206; 12799345 [H]