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The map label for this gene is udk [H]

Identifier: 19746340

GI number: 19746340

Start: 1152080

End: 1152706

Strand: Reverse

Name: udk [H]

Synonym: spyM18_1380

Alternate gene names: 19746340

Gene position: 1152706-1152080 (Counterclockwise)

Preceding gene: 19746342

Following gene: 19746339

Centisome position: 60.83

GC content: 37.0

Gene sequence:

>627_bases
ATGTTTAAAAAACCGATTATTATTGGTGTAACTGGTGGTTCAGGTGGCGGTAAAACAAGTGTGTCACGCGCTATTTTGGA
CAGTTTTCCAAATGCTCGTATTGCAATGATTCAACACGATTCTTACTATAAAGATCAGTCTCACATGAGTTTTGAAGAAA
GGGTCAAGACCAATTATGACCATCCTCTAGCTTTTGATACAGATTTTATGATTCAGCAACTAAAAGAATTATTAGCTGGT
AGACCTGTAGATATTCCTATCTATGATTACAAAAAGCATACCCGCAGTAATACGACCTTTCGTCAGGATCCTCAGGATGT
TATTATTGTTGAAGGTATTCTTGTCCTAGAAGATGAGCGTTTGCGAGATTTGATGGATATCAAGCTCTTTGTAGACACAG
ATGACGATATTCGTATTATTCGTCGTATTAAGCGTGACATGATGGAACGTGGCAGAAGCTTAGAAAGTATTATTGATCAG
TACACAAGCGTGGTAAAGCCTATGTATCATCAGTTTATTGAGCCAAGTAAACGCTATGCTGATATTGTTATTCCAGAGGG
AGTTAGTAATGTCGTTGCTATTGATGTTATTAATAGTAAAATTGCGAGTATTCTTGGAGAAGTATAG

Upstream 100 bases:

>100_bases
CATGCGTCTTCCTTTTACTATTGTTTCTATATTCATTATAGCATTATAGTCTCAATTTTGGTAAAATAGTGAGAAAGACT
TTTTAGATTTGGAGTTTAAA

Downstream 100 bases:

>100_bases
TGGAAGTGGCTGAGTAGATTATTTAAATCTGCTCTTTTATTGTTGTGCTCTTCCTAGAGAAAGGGATCATAAAATAGAAA
TGTTATTAATTTGGCTTGGA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAG
RPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV

Sequences:

>Translated_208_residues
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAG
RPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV
>Mature_208_residues
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAG
RPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=43.4782608695652, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI57863312, Length=207, Percent_Identity=43.4782608695652, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI18699734, Length=214, Percent_Identity=40.6542056074766, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=40, Blast_Score=170, Evalue=6e-43,
Organism=Homo sapiens, GI209863022, Length=154, Percent_Identity=35.7142857142857, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI87082034, Length=206, Percent_Identity=48.0582524271845, Blast_Score=211, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17539894, Length=210, Percent_Identity=40.9523809523809, Blast_Score=170, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17539892, Length=210, Percent_Identity=40.9523809523809, Blast_Score=170, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71981181, Length=209, Percent_Identity=36.8421052631579, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=32.9896907216495, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320223, Length=202, Percent_Identity=26.2376237623762, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24649624, Length=221, Percent_Identity=38.9140271493213, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI221458995, Length=220, Percent_Identity=38.6363636363636, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28573516, Length=196, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI28573514, Length=196, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI28573512, Length=196, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI45550449, Length=196, Percent_Identity=39.2857142857143, Blast_Score=162, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23851; Mature: 23851

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCC
HPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDER
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECEEEECCHH
LRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYA
HHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHE
DIVIPEGVSNVVAIDVINSKIASILGEV
EEECCCCCCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCC
HPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDER
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEECEEEECCHH
LRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYA
HHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHE
DIVIPEGVSNVVAIDVINSKIASILGEV
EEECCCCCCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]