| Definition | Streptococcus pyogenes MGAS8232, complete genome. |
|---|---|
| Accession | NC_003485 |
| Length | 1,895,017 |
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The map label for this gene is inlA [H]
Identifier: 19746333
GI number: 19746333
Start: 1144768
End: 1147146
Strand: Reverse
Name: inlA [H]
Synonym: spyM18_1373
Alternate gene names: 19746333
Gene position: 1147146-1144768 (Counterclockwise)
Preceding gene: 19746335
Following gene: 19746332
Centisome position: 60.53
GC content: 38.21
Gene sequence:
>2379_bases ATGAAAACGAAAAAAGTTATTATTTTAGTTGGTCTATTGTTATCATCTCAGTTGACTTTGATAGCTTGTCAATCACGAGG TAATGGTACATATCCCATTAAAACGAAACAATCACGTAAGGGAATGACGTCAAACAAAATTAAACCGATTAAAAAAAGCA AAAAGATAAACAAGACTCACAAAGGTGTGGCGGGTGTCGATTTTCCTACAGATGATGGGTTTATTTTAACCAAAGACTCA AAAATCTTATCAAAAACAGATCAGGGAATCGTTGTTGACCATGATGGTCATTCGCATTTTATTTTTTATGCCGATTTAAA GGGAAGTCCATTTGAATACCTTATTCCAAAAGGAGCAAGTTTAGCTAAGCCAGCTGTTGCTCAGCAAGCAGCTAGTCAAG GGACTTCTAAAGTAGCAGATCCTCATCACCATTATGAATTTAACCCAGCAGATATTGTGGCTGAAGATGCTTTAGGCTAC ACGGTTCGCCACGATGATCACTTCCATTATATTTTGAAGTCAAGCTTATCAGGTCAGACACAGGCACAAGCTAAACAGGT TGCTACTCGCTTGCCACAAACCAGTAGCCCTGTTTCAACAGTTACAGCTAATGGTATTCCAGGCTTGCATTTCCCAACCT CAGATGGTTTTCAATTTAACGGTCAAGGTATTGTTGGGGTAACAAAAGCCAGTATTTTAGTGAACCACGATGGTCACTTA CATCCTATTTCTTTTGCGGACCTTCGTCAGGGTGGCTGGGCACATGTGGCAGATCAATACGATCCCGCTAAAAAAGCAGA AAAGCCAGCAGAAACCCATCACACACCAGAGCTATCTGAACGTGAAAAGGAATACCAAGAAAAATTAGCTTATTTGGCAG AAAAATTGGGGATTGATCCATCAACTATTAAACGTGTGGAAACACAAGACGGTAAACTTGGTTTGGAATACCCTCACCAT GACCACGCACACGTATTGATGTTATCTGATATTGAAATCGGAAAAGACATTCCAGATCCACATGCTATTGAGCATGCCCG TGAATTGGAAAAACATAAGGTTGGAATGGATACCTTGCGTGCCTTAGGGTTTGATGAAGAAGTGATTTTGGATATCGTTC GCACTCACGATGCTCCAACCCCATTCCCATCAAATGAAAAAGATCTGAATAAGATGAAAGAATGGTTAGCAACGGTTATC AAACTTGACTTGGGCAGCCGTAAAGATCCTTTGCAACGTAAAGGACTTTCACTGTTACCCAACTTAGAAACTTTAGGAAT TGGCTTTACACCAATCAAAGATATCTCACCTGTTTTGCAATTTAAAAAATTGAAACAGTTGTTAATGACAAAAACAGGGG TGACTGATTATAGATTTTTGGATAATATGCCACAGTTAGAAGGCATTGATATTTCACAAAACAATCTCAAAGATATTAGT TTCTTGAGCAAATATAAAAACTTAACTCTAGTAGCGGCTGCTGATAATGGTATTGAAGATATTAGGCCGCTTGGTCAATT ACCAAATCTCAAATTCCTCGTATTGAGTAATAATAAGATTTCTGATTTAAGCCCACTGGCATCGTTACATCAATTGCAAG AATTGCACATTGATAATAATCAGATTACAGATTTAAGCCCTGTTTCTCATAAAGAATCATTGACGGTTGTTGATTTATCA AGAAATGCTGATGTTGACTTAGCAACACTTCAAGCACCCAAATTAGAAACGTTAATGGTCAATGATACCAAGGTTTCTCA TTTGGATTTCTTGAAAAATAATCCTAATCTATCTAGCCTATCTATTAACCGTGCGCAATTGCAATCTCTTGAAGGTATTG AAGCAAGTAGCGTCATTGTCAGAGTAGAAGCAGAAGGTAACCAAATTAAATCGCTTGTGCTTAAAGACAAGCAAGGGTCA CTTACTTTCTTGAATGTGACAGGCAACCAGTTGACTTCTCTAGAAGGTGTTAATAATTTTACAGCACTTGACATTTTAAG CGTGTCTAAAAACCAATTAACAAATGTCAACCTATCTAAACCCAATAAGACAGTTACTAATATTGATATTAGTCATAACA ATATCCCATTGGCAGACCTTAAATTGAACGAGCAACATATTCCAGAAGCCATTGCGAAAAACTTCCCAGCGGTTTACGAA GGTTCTATGGTAGGTAATGGAACAGCTGAAGAAAAAGCAGCTATGGCTACTAAGGCGAAAGAAAGTGCTCAAGAAGCATC GGAATCACATGACTACAACCATAATCATACTTATGAAGATGAAGAAGGTCATGCTCACGAGCACAGAGACAAAGATGATC ACGACCATGAACATGAGGATGAAAATGAAGCTAAAGATGAGCAAAACCATGCTGACTAA
Upstream 100 bases:
>100_bases GAGCTCCAACTCGTCAACAACTAATAGTTATCCTAAAAAGAGCTTGAGGAAAAACAAGTGATGTGATATACTTAACTAGT TAAATAAAAAGGAGGGTTGA
Downstream 100 bases:
>100_bases ACTAATCTAAGAATAACCCTATCCAACTGAACCGTCCTAATGACACCATTGTTGACTATCAAGAAAACCTCAAGAATAAC CTTGAGGTTTTTTTGAAATA
Product: internalin A precursor
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 792; Mature: 792
Protein sequence:
>792_residues MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKINKTHKGVAGVDFPTDDGFILTKDS KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQFNGQGIVGVTKASILVNHDGHL HPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWLATVI KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS LTFLNVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYE GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
Sequences:
>Translated_792_residues MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKINKTHKGVAGVDFPTDDGFILTKDS KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQFNGQGIVGVTKASILVNHDGHL HPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWLATVI KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS LTFLNVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYE GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD >Mature_792_residues MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKINKTHKGVAGVDFPTDDGFILTKDS KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQFNGQGIVGVTKASILVNHDGHL HPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWLATVI KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS LTFLNVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYE GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
Specific function: Mediates the entry of Listeria monocytogenes into cells [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 14 LRR (leucine-rich) repeats [H]
Homologues:
Organism=Homo sapiens, GI4506013, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014755 - InterPro: IPR019948 - InterPro: IPR014756 - InterPro: IPR001611 - InterPro: IPR013378 - InterPro: IPR019931 - InterPro: IPR012569 - InterPro: IPR001899 [H]
Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]
EC number: NA
Molecular weight: Translated: 87441; Mature: 87441
Theoretical pI: Translated: 6.45; Mature: 6.45
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKINKTH CCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHH KGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGAS CCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCCCC LAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQT CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEEEHHCCCCCH QAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQFNGQGIVGVTKASILVNHDGHL HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEECCCEEEEEEEEEEEECCCCCC HPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDP CCCCHHHHCCCCCEECCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH STIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLR HHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH ALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWLATVIKLDLGSRKDPLQRKGLSLLP HCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC NLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHH FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNN HHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC QITDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSL CCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCCEE SINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLNVTGNQLTSLEGVNNF ECCHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCC TALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYE EEEEEEECCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHCCCCCEEC GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHED CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC ENEAKDEQNHAD HHHHHHHHCCCC >Mature Secondary Structure MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKINKTH CCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHH KGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGAS CCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCCCC LAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQT CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEEEHHCCCCCH QAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQFNGQGIVGVTKASILVNHDGHL HHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCEECCCEEEEEEEEEEEECCCCCC HPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDP CCCCHHHHCCCCCEECCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH STIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLR HHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH ALGFDEEVILDIVRTHDAPTPFPSNEKDLNKMKEWLATVIKLDLGSRKDPLQRKGLSLLP HCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC NLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHH FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNN HHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC QITDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSL CCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCCEE SINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLNVTGNQLTSLEGVNNF ECCHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCC TALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYE EEEEEEECCCCCCCEEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHCCCCCEEC GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHED CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC ENEAKDEQNHAD HHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9541569 [H]