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The map label for this gene is aroA [H]

Identifier: 19746325

GI number: 19746325

Start: 1135200

End: 1136483

Strand: Reverse

Name: aroA [H]

Synonym: spyM18_1364

Alternate gene names: 19746325

Gene position: 1136483-1135200 (Counterclockwise)

Preceding gene: 19746326

Following gene: 19746324

Centisome position: 59.97

GC content: 41.2

Gene sequence:

>1284_bases
ATGAAATTGCGAACAAATGCAGGACCATTACAGGGAACGATTCAAGTTCCAGGAGACAAGTCCATTAGTCACCGGGCAGT
CATATTAGGAGCTGTTGCTAAAGGGGAAACACGAGTAAAAGGACTCTTAAAAGGAGAAGACGTGCTTTCCACGATTCAAG
CCTTTAGGAATTTGGGGGTCCGTATCGAAGAAAAAGATGACCAGCTTGTGATAGAAGGTCAAGGTTTTCAAGGATTGACC
GCTCCTTGTCAGACACTTAATATGGGAAATTCTGGAACCTCTATGCGCCTCATTGCTGGCTTATTGGCAGGTCAACCTTT
TAGTGTCAAAATGATTGGCGATGAAAGCTTATCCAAACGTCCTATGGATCGGATTGTTTATCCGTTAAAGCAAATGGGGG
TTGAGATATCTGGAGAAACAGATAGGCAATTTCCTCCACTACAATTGCAAGGTAATCGTAATTTACAACCAATCACATAT
ACTTTGCCTATCTCTTCTGCTCAGGTTAAGTCAGCTATTTTGTTAGCAGCTTTGCAAGCAAAAGGAACAACACAGGTTGT
TGAAAAAGAGATTACTCGAAACCATACAGAAGAAATGATTCAACAATTTGGTGGACGATTGATAGTTGATGGTAAACGCA
TTACTTTGGTGGGACCCCAGCAGCTCACTGCTCAAGAGATAACTGTCCCCGGAGATATTTCTAGTGCAGCTTTTTGGCTT
GTCGCCGGCTTAATTATTCCTGGTTCGGAGCTCCTTTTAAAGAATGTTGGAGTCAATCCGACACGAACAGGGATTCTTGA
AGTGGTTGAAAAAATGGGAGCACAGATTGTCTATGAAGATATGAATAAGAAAGAGCAAGTAACTAGTATTCGAGTGGTAT
ATTCTCACTTGAAAGGAACTATCATATCAGGAGGTCTTATCCCTCGATTGATTGATGAACTTCCCATCATTGCACTTCTT
GCAACCCAAGCACAAGGAACAACCTGTATTAAAGATGCTCAAGAATTACGAGTCAAAGAAACAGATCGTATTCAAGTAGT
AACTGATATTCTTAACAGTATGGGAGCTAATATCAAAGCGACAGCAGATGGCATGATTATCAAAGGCCCTACGGTACTAT
ATGGGGCTAACACAAGTACCTATGGAGATCATCGTATTGGTATGATGACAGCAATTACAGCCTTGCTTGTTAAACAAGGA
CAGGTCCATTTGGATAAAGAAGAAGCCATCATGACGTCTTATCCGACGTTTTTCAAAGATTTAGAAAGGCTGTGTCATGA
CTAA

Upstream 100 bases:

>100_bases
ATAATAAGTCGTGGAGTGAGAAACTATTTTCTTGCTTCATTTTTTATGAGGATAAATAGAAAATCATTGATCTTAGCAAA
TAGAAAGGCAGATAAAACGG

Downstream 100 bases:

>100_bases
AGTGTTATTGGGATTTATGGGAGTGGGGAAAACAACGGTTTCGAAACACCTAAGTATGCACTGTAAAGATATGGATGCTA
TTATTGAAGCTAAAATCGGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLT
APCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWL
VAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALL
ATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAITALLVKQG
QVHLDKEEAIMTSYPTFFKDLERLCHD

Sequences:

>Translated_427_residues
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLT
APCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWL
VAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALL
ATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAITALLVKQG
QVHLDKEEAIMTSYPTFFKDLERLCHD
>Mature_427_residues
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLT
APCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWL
VAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALL
ATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAITALLVKQG
QVHLDKEEAIMTSYPTFFKDLERLCHD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=431, Percent_Identity=29.0023201856148, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=435, Percent_Identity=24.367816091954, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46300; Mature: 46300

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGV
CCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHCCC
RIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKR
EEECCCCEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQA
CHHHHHHHHHHCCEEECCCCCCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
KGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWL
CCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCCCCHHHHHHH
VAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGT
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEHHCCCHHHHHHHHHHHHHHCCE
IISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKA
EECCCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
TADGMIIKGPTVLYGANTSTYGDHRIGMMTAITALLVKQGQVHLDKEEAIMTSYPTFFKD
ECCCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHCCCHHHHH
LERLCHD
HHHHHCC
>Mature Secondary Structure
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGV
CCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHCCC
RIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKR
EEECCCCEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQA
CHHHHHHHHHHCCEEECCCCCCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
KGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWL
CCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCCCCHHHHHHH
VAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGT
HHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEHHCCCHHHHHHHHHHHHHHCCE
IISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKA
EECCCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
TADGMIIKGPTVLYGANTSTYGDHRIGMMTAITALLVKQGQVHLDKEEAIMTSYPTFFKD
ECCCEEEECCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHCCCHHHHH
LERLCHD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]