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The map label for this gene is bglA [H]

Identifier: 19746305

GI number: 19746305

Start: 1116337

End: 1117737

Strand: Reverse

Name: bglA [H]

Synonym: spyM18_1338

Alternate gene names: 19746305

Gene position: 1117737-1116337 (Counterclockwise)

Preceding gene: 19746307

Following gene: 19746304

Centisome position: 58.98

GC content: 40.69

Gene sequence:

>1401_bases
ATGAAACAAAGAAAACACCGTTATCAATTTCCAGATGGCTTTTTATGGGGAAGTTCCACATCTGGGCCTCAAAGCGAAGG
AACGGTTCCTGGAGATGGCAAAGGACCTAGCAACTGGGATTACTGGTTTAGTATTGAGTCAGCTAAGTTTCATCACCAAA
TTGGTCCAGAAAAAACCTCAACCTTTTATGAAAACTATAAGGGTGACATTGCCCTTTTGAAAGAAACAGGCCACACGATT
TTTCGGACCTCAATCCAGTGGTCTCGATTGATTCCAGAAGGAGTCGGGGAGGTTAATCCAAAGGCGGTGACATTTTACCG
AGAAGTATTTCAAGACATTATTGCTCAAGGTATTAAATTGATTGTTAACTTCTATCATTTTGACCTCCCCTATGCCTTGC
AAGAAAAAGGTGGCTGGGAAAACAAAGCTACTGTCTGGGCTTATGAAACCTACGCAAAAACCTGTTTTGAGCTTTTTGGT
GATTTAGTAAACACTTGGATTACCTTTAATGAACCGATTGTTCCAGTCGAATGTGGCTATTTAGGTTATTATCACTACCC
TTGTAAAGTAGATGCCAAGGCAGCAGTTCAAGTGGCTTACAACACACAACTGGCCAGTTCACTGGCGGTCAAAGCTTGTC
ATGAGCTTCATTCCGACCACAAGATTAGTATTGTACTTAACATGACACCTGCTTATCCTCGGAGTGATGCTCCTGAAGAT
GTCAAGGCTGCTAGAATCGCAGAGCTTTTCCAAACCAAATCCTTCCTAGATCCATCAGTTTTGGGTGTTTACCCAGCAGA
GTTAGTTTCCATTTTAGAGGAAGCTGATTTATTACCTCAATATAGTGCTGATGAATTAGAGATTATCAAAAACAATACTG
TTGATTTTTTGGGAGTTAATTATTATCAGCCTTTGCGGGTTCAGGCACCTAGTAAGTCACAGCAAGAGGGGGACCCCCTT
ATCTTAGATATTTATTTTGAACCTTATGATATGCCTGGTAAAAAAGTCAATCCTCACCGGGGTTGGGAAATTTATGAACC
AGGACTTTATGATATTGCCCTTAATTTAAAAGAACATTATGGTAACATCGAATGGCTAGTCACGGAAAATGGTATGGGTG
TCGAAGGTGAAGAAGCTTTTTTAGCAGATGGCCAGATACAAGATGACTACCGCATCACCTTTATCGAGGATCATCTTATC
CAGCTTCATAAGGCTTTGGGAGAAGGAGCCAACTGCAAAGGCTACCTCTTGTGGACTTTTATTGATTGCTGGTCTTGGTT
AAATGCTTATAAAAACCGATATGGTTTGGTAGCTTTGGATTTAGAGAGTCAAAAGCGAACCATAAAAAAATCAGGTTACT
GGTTTAAGGCGTTGAGCGAGTCAAATGGTTTTGATAAATAG

Upstream 100 bases:

>100_bases
TCCGTGATGATAAGGAAAAAACAGATTTTTTAAAGCGTTTACATCACCTGTTTTTCTTCTTATAATAAAAAGAGAAGTGA
GCAAAGAAAGGACAAAGGAT

Downstream 100 bases:

>100_bases
GAGGCAATATGGTTGATTTAGGATTTTCTCTATACCCTGAGCGGTATGATGTTACCAAGAGTAAAGCTTATATTGACTTA
TGTCATAGCTATGGAGCCAA

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTI
FRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKLIVNFYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHELHSDHKISIVLNMTPAYPRSDAPED
VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPL
ILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLI
QLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK

Sequences:

>Translated_466_residues
MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTI
FRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKLIVNFYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHELHSDHKISIVLNMTPAYPRSDAPED
VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPL
ILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLI
QLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK
>Mature_466_residues
MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTI
FRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKLIVNFYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHELHSDHKISIVLNMTPAYPRSDAPED
VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPL
ILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLI
QLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=482, Percent_Identity=29.8755186721992, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI13273313, Length=459, Percent_Identity=30.2832244008715, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI32481206, Length=485, Percent_Identity=28.8659793814433, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI28376633, Length=474, Percent_Identity=28.9029535864979, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=26.6802443991853, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1789070, Length=481, Percent_Identity=32.8482328482328, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI2367270, Length=475, Percent_Identity=33.0526315789474, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI2367174, Length=489, Percent_Identity=29.6523517382413, Blast_Score=192, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17552856, Length=477, Percent_Identity=31.8658280922432, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17539390, Length=469, Percent_Identity=30.7036247334755, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21356577, Length=485, Percent_Identity=27.2164948453608, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53156; Mature: 53156

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTS
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHH
TFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKL
HHHHCCCCCEEEEECCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVNFYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFGDLVNTWITFNEPIVPVECGY
HHHHHHCCCCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCEEEEECCE
LGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHELHSDHKISIVLNMTPAYPRSDAPED
EEEEECCCEECCCEEEEEEECHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVN
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECC
YYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHY
CCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEEEEEHHHC
GNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLIQLHKALGEGANCKGYLLWTF
CCEEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEHHH
IDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure
MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTS
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHH
TFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKL
HHHHCCCCCEEEEECCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVNFYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFGDLVNTWITFNEPIVPVECGY
HHHHHHCCCCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCEEEEECCE
LGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHELHSDHKISIVLNMTPAYPRSDAPED
EEEEECCCEECCCEEEEEEECHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHH
VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVN
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECC
YYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHY
CCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEEEEEEHHHC
GNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLIQLHKALGEGANCKGYLLWTF
CCEEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEHHH
IDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK
HHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]