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The map label for this gene is gmuC [H]

Identifier: 19746299

GI number: 19746299

Start: 1110462

End: 1111841

Strand: Reverse

Name: gmuC [H]

Synonym: spyM18_1331

Alternate gene names: 19746299

Gene position: 1111841-1110462 (Counterclockwise)

Preceding gene: 19746300

Following gene: 19746298

Centisome position: 58.67

GC content: 39.86

Gene sequence:

>1380_bases
ATGTCGCATTTTTCTGATAAGTTTATGGAGATTTCAGGAAAAATTGGGTCACAACGGCATTTAGTAGCTATTCGTGATTC
CTTTATTTCAATGATGCCTATTACCATGGCAGGTTCAGTTGCTGTCTTATTGAACGTTTTTTTACGCGATATTCCAAACA
ATATGGGATGGACAGGATTTGCAAAAGCTATGCAACCTGTTATCGACATCAATGGCTATGTTTATTTTGGGACAATTGGT
ATCATGGCGCTCTTTTTTGCCTTTGCTTTCGGTTACAATTTAGCTGTTATGCATAAGATTAATCCATTGGCAGGAGGATT
GATTTCTTTTGGCTCATTTATTGCCACCCTACCTCAGACTTTAACCATTTCGACACCACTTGAAAATGCCTCTGCTAACC
TAATTAGCAATTTAAAAGAAATGGGGCTTTCAGTCGTTACTGCGGGTGGAGGTTCAAGTATTGAAACTAGTCAATGGGGA
GCAATAGCTCTAAAGTATGTCGGTGCTACAGGCTTGTTCACAGCTTTAATTATTGGCTTTTTATCAAGTTTTGTGTATGC
GGCTTTGACCAAACGTAATATTACCATTACCTTACCAGATAATGTACCACCTGCGGTTAATAAAGCCTTTGCTGCCATTA
TTCCAGGAACAGTTGCGATTTACGCTTCGGCAATTTTCGCCTACCTCATCTTTGCATTAACAGGTTCTTCCCTAAGTGAT
GTCATTTCAACCTATATCCAATTACCATTACTAGGCTTATCACAGGGTATTGGTTCAGTTATCTTGTTAACCTTCTTAGT
TCAACTGCTCTGGTTCTTCGGCTTGCATGGTCATAATGTCTTAGCCCCAGTGATGGATGGTATTTATATGGTAGCTTTAA
CAGAAAATACAGCTGCTTACAATACAGCGCATAGCGCTGCTAATTTACCATACCTTTGGACACGCGGGTCCTTTGATGCT
TATGCTCAAATGGGTGGTTCAGGAGTAACCTTGGCATTGATTATTGCTATCTTCATATTCTCAAAACGAGAAGAGCATAA
AACCATTGCCAAATTGTCCGCACCAATGGGTGTTTTCAATATCAACGAACCAATTACATTTGGGATGCCAATTGTTTTGA
ATCCAACCTTTGTGATTCCATGGCTAATTGTGCCACCAATTTGTGCTAGCATAGCTTATTTTGCTACTGCAATAGGTTTG
ATTCCACCGGTATTCTTATCAGTACCTTGGATTACCCCTGTTGGACTTTATGCTTACCTAGCTACTGGAGGTAATATTAT
GGCAGGTTTGGTTTCACTGTTTAACCTCTTTGTTGCCTTCCTTATCTGGGCACCATTTGTCATTTTGGCCAATAAAGAAA
AAGCGAGTGACCTTGCATGA

Upstream 100 bases:

>100_bases
ACGTTTAACAAGGATGATTTTGAGATAATTGTGTTAGGCAGACACCGCTGCTTTTAAGGTTACCTTTGTTACATTAAAAA
ATAAAAAGAGGAGAAGATTT

Downstream 100 bases:

>100_bases
CAGAAAAAAATGGAGCAACTTTTTTAATGGCTGTTGGCTTTTTTCTCATTGCCATTAGTCCGATGGTTGGTAACAAATAC
TTACACATAGTGACGGGACT

Product: PTS system IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIG
IMALFFAFAFGYNLAVMHKINPLAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWG
AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSD
VISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDA
YAQMGGSGVTLALIIAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGL
IPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILANKEKASDLA

Sequences:

>Translated_459_residues
MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIG
IMALFFAFAFGYNLAVMHKINPLAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWG
AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSD
VISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDA
YAQMGGSGVTLALIIAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGL
IPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILANKEKASDLA
>Mature_458_residues
SHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGI
MALFFAFAFGYNLAVMHKINPLAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWGA
IALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSDV
ISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAY
AQMGGSGVTLALIIAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGLI
PPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILANKEKASDLA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=460, Percent_Identity=35, Blast_Score=246, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 49011; Mature: 48880

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRDIPNNMGWTGF
CCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINPLAGGLISFGSFIATLPQT
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
LTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWGAIALKYVGATGLFTALIIGF
EEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHEEHHCHHHHHHHHHHHH
LSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSD
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
VISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEEECCCCHH
NTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALIIAIFIFSKREEHKTIAKLSAPMGVFN
CCCHHCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEE
INEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGLIPPVFLSVPWITPVGLYAYL
CCCCCEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATGGNIMAGLVSLFNLFVAFLIWAPFVILANKEKASDLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCHHCCCCC
>Mature Secondary Structure 
SHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLLNVFLRDIPNNMGWTGF
CCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINPLAGGLISFGSFIATLPQT
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCC
LTISTPLENASANLISNLKEMGLSVVTAGGGSSIETSQWGAIALKYVGATGLFTALIIGF
EEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHEEHHCHHHHHHHHHHHH
LSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTVAIYASAIFAYLIFALTGSSLSD
HHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHH
VISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLHGHNVLAPVMDGIYMVALTENTAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEEECCCCHH
NTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALIIAIFIFSKREEHKTIAKLSAPMGVFN
CCCHHCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEE
INEPITFGMPIVLNPTFVIPWLIVPPICASIAYFATAIGLIPPVFLSVPWITPVGLYAYL
CCCCCEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ATGGNIMAGLVSLFNLFVAFLIWAPFVILANKEKASDLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]