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The map label for this gene is citC [H]

Identifier: 19746128

GI number: 19746128

Start: 954309

End: 955361

Strand: Reverse

Name: citC [H]

Synonym: spyM18_1143

Alternate gene names: 19746128

Gene position: 955361-954309 (Counterclockwise)

Preceding gene: 19746129

Following gene: 19746118

Centisome position: 50.41

GC content: 38.84

Gene sequence:

>1053_bases
ATGCCTTACTACACTATTTCAAAAGTCTTTCCTTCAGATAAAACGACAATGGCTAGTGTAAAGAACCTGCTTCATCAAGA
AGGTATTCGTTTGGATGCTCATTTAGATTATACTTGTGCCATCATGAATGCGCAAAATGATGTGATTGCTACCGGTTCTT
ACTTTGGAAATAGCTTGCGCTGTCTTTGCGTATCCAGTGCCTATCAAGGTGAAGGACTTCTTAATAGGATTGTGAGTCAT
CTCATTGATGAAGAATATGCCCTTGGCAACTATCATCTTTTTGTTTATACGAAGACCTCTTCTGCTGCTTTTTTCAAAGA
TCTTGGTTTTACTGAAATTGTCCATATCGACAATCACATCAGTTTCTTGGAAAATAAAAAAACTGGTTTTCAAGATTATC
TGATGACACTTAATAAGCCTGAGCAAACACCTGGTAAAGTCGCTGCTATTGTTATCAACGCTAACCCCTTTACCTTAGGG
CATCAATTTTTAGTAGAGAAAGCTGCAAGAGAAAATGATTGGGTTCATCTGTTTATGGTCAGTGAAGACCGCAGTCTAAT
TCCTTTTTCGGTGAGAAAGAGGTTGATTCAAGAAGGTCTAGCTCATCTTGATAATGTCATATATCATGAAACAGGTCCTT
ATTTGATTAGCCAAGCGACTTTCCCAGCCTATTTCCAAAAAGAAGACAATGACGTGATTAAGAGCCAAGCCTTGCTGGAT
ACCGCTATTTTTCTAAAGATTGCTCAAACCTTACAGATTACAAAAAGATACGTTGGAGAAGAGCCAACCAGCCGAGTAAC
TGCTATTTACAATGAAATCATGGCAGAGCAGTTGCAGCAAGCTGGTATCCTCCTAGATATTTTGCCAAGGAAAGCTATCA
ATCAGCAGCAAGATCCTATCAGTGCCTCAACGGCTAGGCAGGCATTGAAAGATAATGATTGGGACCTTCTGGCAAAACTC
CTTCCTAAAACTTCTTTAGATTATTTTTGTTCGCTAGAAGCCCAACCCATTATTAAAAAGATACAAGCCACTTCATCTGT
CAAACATTACTAA

Upstream 100 bases:

>100_bases
AAATGGCGTTGATAAAAAACAGAGTTGCCTTTAGATAGATCAGCCTGTTTTGGTACTAAGTTATGTTATGATTCAATAAA
ATTGAAGATAAGGAGAAGAA

Downstream 100 bases:

>100_bases
GATAAAAAACCTATCTGATTATCAAAATCAGGTAGGTTTTTGGTATTGTTCTTACAGCAAATGCGTTTCACCAAGGAGAT
TAATGGTTAAGAGGATTAGT

Product: citrate lyase synthetase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNAQNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSH
LIDEEYALGNYHLFVYTKTSSAAFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQATFPAYFQKEDNDVIKSQALLD
TAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAEQLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKL
LPKTSLDYFCSLEAQPIIKKIQATSSVKHY

Sequences:

>Translated_350_residues
MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNAQNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSH
LIDEEYALGNYHLFVYTKTSSAAFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQATFPAYFQKEDNDVIKSQALLD
TAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAEQLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKL
LPKTSLDYFCSLEAQPIIKKIQATSSVKHY
>Mature_349_residues
PYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNAQNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHL
IDEEYALGNYHLFVYTKTSSAAFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLGH
QFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQATFPAYFQKEDNDVIKSQALLDT
AIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAEQLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKLL
PKTSLDYFCSLEAQPIIKKIQATSSVKHY

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=330, Percent_Identity=34.8484848484849, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 39533; Mature: 39401

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNAQNDVIATGSYFGNSLR
CCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCEEEECHHCCCCEE
CLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSAAFFKDLGFTEIVHIDNHI
EEEECCCCCCCHHHHHHHHHHHCCCEECCCEEEEEEEECCCHHHHHHCCCEEEEEECCHH
SFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLGHQFLVEKAARENDWVHLFMV
HHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEE
SEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQATFPAYFQKEDNDVIKSQALLD
ECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCHHHCCCCCHHHHHHHHHH
TAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAEQLQQAGILLDILPRKAINQQQDPI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHCHHHCCCCCCCC
SASTARQALKDNDWDLLAKLLPKTSLDYFCSLEAQPIIKKIQATSSVKHY
CHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNAQNDVIATGSYFGNSLR
CCEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCEEEECHHCCCCEE
CLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSAAFFKDLGFTEIVHIDNHI
EEEECCCCCCCHHHHHHHHHHHCCCEECCCEEEEEEEECCCHHHHHHCCCEEEEEECCHH
SFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLGHQFLVEKAARENDWVHLFMV
HHHHCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEE
SEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQATFPAYFQKEDNDVIKSQALLD
ECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCHHHCCCCCHHHHHHHHHH
TAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAEQLQQAGILLDILPRKAINQQQDPI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHCHHHCCCCCCCC
SASTARQALKDNDWDLLAKLLPKTSLDYFCSLEAQPIIKKIQATSSVKHY
CHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]