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The map label for this gene is tdk [H]

Identifier: 197294747

GI number: 197294747

Start: 731495

End: 732094

Strand: Reverse

Name: tdk [H]

Synonym: PAa_0713

Alternate gene names: 197294747

Gene position: 732094-731495 (Counterclockwise)

Preceding gene: 197294748

Following gene: 197294746

Centisome position: 83.2

GC content: 32.0

Gene sequence:

>600_bases
ATGCCAAAAGAACAACAAGGATTCATTGAAGTTATTTGTGGTCCTATGTTTGCAGGAAAAACAGAAGCGTTAATAAAACG
CTATCAAGAAGCTCAAAAATTGAAAAAAAATATTCTATCATTTAAGCCTCGCATTGATAATCGTTATTCTTCTGAAGGAT
TCATTGTTTCTCACAGTCAAAATAAATTTCCTGCGATTTTAATTGATCAAAGTCGCGATATTCTCCCTTTTGTTACTCCA
GAAACTGACTTAATAATCATTGATGAAGTTCAATTTTTAGATAATGATATTTTTGGGATTGTTGATTATTTGGCTAACCA
AAATATTCAAATTATTTTAGCAGGTTTAGATCTTGATTTTAAAGGCAAACCCTTCGGACCTATGCCTTATTTGTTAGCGT
TAGCAGAAGTTGTGACTAAGTTAACTGCTATTTGTGCTGTTAGTGGTAAAAAAGCTACTAAAACACAAAGATTAATTAAC
GGAAAACCAGCCAAAAGCAATGATTCAACAATTTTAGTAGGCGGTCAAGAATATCATGAACCTCGTTGCCGCCGTCATCA
TGAATTATTAGACGTTGATAAAAAAACCATTAATTTATAA

Upstream 100 bases:

>100_bases
TTATAATGTGAACACTCAAAAATCAGTTGACCAAAAAGAAAAAAATAAATAACTTCCAAAAACTCATAATAATGAAGTTA
ATAGAAGAGGTTTTAAAATA

Downstream 100 bases:

>100_bases
AAGTATTAAAAAAACAGGTGTATTTTAAGTTTTTATGACTCAAAATGACAAAAATCTCTTTTTTATGAAAGCAGCTTTTC
AAGAAGCTTATAAAGCTTAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPKEQQGFIEVICGPMFAGKTEALIKRYQEAQKLKKNILSFKPRIDNRYSSEGFIVSHSQNKFPAILIDQSRDILPFVTP
ETDLIIIDEVQFLDNDIFGIVDYLANQNIQIILAGLDLDFKGKPFGPMPYLLALAEVVTKLTAICAVSGKKATKTQRLIN
GKPAKSNDSTILVGGQEYHEPRCRRHHELLDVDKKTINL

Sequences:

>Translated_199_residues
MPKEQQGFIEVICGPMFAGKTEALIKRYQEAQKLKKNILSFKPRIDNRYSSEGFIVSHSQNKFPAILIDQSRDILPFVTP
ETDLIIIDEVQFLDNDIFGIVDYLANQNIQIILAGLDLDFKGKPFGPMPYLLALAEVVTKLTAICAVSGKKATKTQRLIN
GKPAKSNDSTILVGGQEYHEPRCRRHHELLDVDKKTINL
>Mature_198_residues
PKEQQGFIEVICGPMFAGKTEALIKRYQEAQKLKKNILSFKPRIDNRYSSEGFIVSHSQNKFPAILIDQSRDILPFVTPE
TDLIIIDEVQFLDNDIFGIVDYLANQNIQIILAGLDLDFKGKPFGPMPYLLALAEVVTKLTAICAVSGKKATKTQRLING
KPAKSNDSTILVGGQEYHEPRCRRHHELLDVDKKTINL

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=183, Percent_Identity=34.9726775956284, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1787490, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17543396, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22397; Mature: 22266

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKEQQGFIEVICGPMFAGKTEALIKRYQEAQKLKKNILSFKPRIDNRYSSEGFIVSHSQ
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC
NKFPAILIDQSRDILPFVTPETDLIIIDEVQFLDNDIFGIVDYLANQNIQIILAGLDLDF
CCCCEEEEECCCCCCEEECCCCCEEEEECHHHHCCHHHHHHHHHHCCCEEEEEEECCCCC
KGKPFGPMPYLLALAEVVTKLTAICAVSGKKATKTQRLINGKPAKSNDSTILVGGQEYHE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCHHHCC
PRCRRHHELLDVDKKTINL
CHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
PKEQQGFIEVICGPMFAGKTEALIKRYQEAQKLKKNILSFKPRIDNRYSSEGFIVSHSQ
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC
NKFPAILIDQSRDILPFVTPETDLIIIDEVQFLDNDIFGIVDYLANQNIQIILAGLDLDF
CCCCEEEEECCCCCCEEECCCCCEEEEECHHHHCCHHHHHHHHHHCCCEEEEEEECCCCC
KGKPFGPMPYLLALAEVVTKLTAICAVSGKKATKTQRLINGKPAKSNDSTILVGGQEYHE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCHHHCC
PRCRRHHELLDVDKKTINL
CHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA