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The map label for this gene is rpoC [H]

Identifier: 197294698

GI number: 197294698

Start: 661262

End: 665326

Strand: Reverse

Name: rpoC [H]

Synonym: PAa_0664

Alternate gene names: 197294698

Gene position: 665326-661262 (Counterclockwise)

Preceding gene: 197294699

Following gene: 197294697

Centisome position: 75.61

GC content: 31.56

Gene sequence:

>4065_bases
ATGAATGATAATAAATTATTTAGATCAATAGAGACTCTAAATTTTTCTTTTCAAACTTTGGAAAAATTAAAACTTTCAGG
AATCAATAATTTAGAAGATTTTAATACTTTTTCTTTAGAAGAACTAAGGTCTTTATTGCAAGAAACTTTTTTGGAAGTTT
TGCCTATTTTAAAACAATTCGCCTTACCACGTGATTTAAAAAAATTAAACCTTAACAACGATATTATTGAAAAATTGACT
CTTTTAGGTATTTATGATTTCGAACAACTTTTAAAAGCAGAATTACCAGTTTTAACCAAAACTTTTCAAACTGATCTCGC
TTCTTGGCGCGCATTAAACGAACTTTTTGAATTGTACCAACATCTACCTCCAGAAGGCTTAATTGTATCTAATAAAAAAT
ACGGTAGTAGAGATTATGATTATTTCAAAATTCGTTTAGCATCTCCTGAAGAAATTCGTCAATGGTCTTATGGGGAGGTT
ACAAGTTACGAAACAATTAATTATCGTACTTATAAACCTGAACCTGGCGGCTTATTTTGTCAGAAAATCTTTGGTCCAGT
AGTTGATTATAGATGTGCTTGTTCCAAAAAACAAATTAGCACCAAAAGCCAATTTTGTAATAAATGCCATGTGGAATTTA
CTGAAACTAAAGTCAGAAGAGAAAGAATGGGACACATCGAATTACAAGCGCCAGTTGTACATACTTGGTATTTTAATTCT
TCTCCTAGTCGTTTGGCCGTTATTTTAAACATTAAAGCTAAAGCTTTAGAAGAAATAATTTATTATATTTCTTATGTTGT
AATTGACCCTGGTAAAACAGATTTTAAAGAAAAAGAAATTATTTCCAAAAGTCAATATAGTCAAAATTTAGATATTTTTG
GCCCTAATGGTTTTGTTGCTTTAACTGGTGCTGAAGCAATTAGAAAATTATTGGAAAACCTTGATTTAGAAAAAACAATT
AAAATCCTTAGAAAAAACTTATCAGAAGTTTCTAAACAAAAACGAGGTGCTTTGATTAAAAGATTAGAAATTATGGAATC
TTTGTATCAATCTGATAATAATCCTGAGTGGATGGTAATGGACGTTATTCCTGTTTTGCCACCAGGATTAAGACCCATGG
TCCCTTTAGATGGTGGTCGTTTCGCCACTACTGAAATTAATGATTTATATCGTCGTATTTTAAATCGCAACAATCGTTTA
AAAAAACAAATGCTTCAAAAAGCTCCAAGTTTAATTATCCAAAATGAAAAAAGAATGTTGCAAGAAGCAGTTGATTGTTT
GTTTGATGGTGATAGAAACGTTAAGAAAAATGTTAATAATATAGAAAAAAACCGCCCGCTTAAATCTTTATCGGAAATGT
TGCGTGGAAAACAAGGACGCTTTCGTCAAAATCTTTTAGGAAAAAGGGTTGATTATTCTGGCCGTTCAGTAATTATTGTA
GGTCCTGACCTTAAAATGCATCAATGTGGTATTCCTCGAGAAATGGCAATTATCTTATTCAAACCTTTTATTTTGAAAAA
ATTGCAAGAAACTAAGGGAATTGACAAAAAAAATGCCAATTCTATTTATGAAAAAATGAATGAAGAAGTTTGGAACGTTT
TAGAAGAAGTAGTCAAAGAACATCCTGTTCTTCTTAATCGCGCCCCTACTTTGCACCGTTTAGGGATTCAAGCTTTTGAT
CCTAAATTAATCGACGGCAAAGCTATTCGTTTGCATCCTTTAGTAACCCCTGCCTTTAATGCTGATTTCGATGGTGACCA
AATGGCCGTTTATATACCTCTTTCTTTGGAAGCTCAAGCCGAAGCTCGTTTGTTAATGCTTGCTTCTAATAATATTTTAG
ACCCTAAAAATGGTAGTCCCGTTGTTACCCCTTCGCAAGATATGGTTTTAGGAAACTATTATTTAACTATTGAAACTAAA
AAAGATCTTTTCGCTAAAGACCTCAAAGTTTCTCAAGAAGATGCAGCTAATCACCAACAAAAACATCGCAATGAGGGAGC
TTTTTTTGCTGATATCAACGAAGTAAAAATCGCTTATCAAAGCAAAGAAATAGGACTTCATACGCGTATTTTTATCAAAC
CGCGATCAATTAACTTATCTTTTACTGAGGAACAAAAAGAAAAATATTTAATGACTACTTTAGGTAAATTAATTTTTAAT
AACATTTTACCTCCTAATTTTCCTTACATTAATGAACCAACTGAAACTAATTTATACGTTAAAACTCCTGACAGATATTT
TTTAAATCCAGGAGAAAACCCTAAATCATTTTTGAAAAAATTACCCCTCCCAAAACCTTTTAATAAAAAGTTCTTATCGA
TGATTATTGCTTGTTTTTTTAAACAAATGAAAATTACAGAAACTTCGAAAATGTTAGATAAAATTAAAGATTTAGGTTTT
AAATATTCTACTATTGCAGGAATTACTGTTTCTTTTGCTGATATTAATATTTATTCTGAAAAAGACAAATTATTATCTAA
AGTTGAAAAACGCAATAATCAAATTGAAAATTGGTATAAACAAGGATTTTTAACAGATGCAGAACGTCGCCGTTTAGTTA
TTAACGAATGGAAAACAATCCGCGACCAAATTCAAGAAGGATTAATGAAAGAATTCCCAAATGACAACCATATTTTTATG
ATGAGCGAAAGTGGTGCTCGTGGTAGTGTTTCTAACTTTACTCAATTAGCAGGGATGAGGGGATTGATGAATAACCCTAA
AGGGGAAATTATTGAAGTTCCCGTGAAAGCCTCTTTTAGAGAAGGTTTGAAAGTTTCTGAATTTTTCATTTCTACTCACG
GAGCCCGCAAAGGTTCAACCGACACTGCTTTAAAAACTGCTGAATCAGGTTATTTAACACGTCGTTTAGTTGATGTTACT
CAAGATGTTGTGGTTATTAAAGAAGATTGCGGAAGTGATCATAGTTTTTTTGTTGAAGCTATGATGATCGACGGCAAAGA
AATTATTTCTTTAAAAAACCGTATTTTGGGTCGTTGTGCTAGTCGTGATGTTTTGCATCCTAAAACAGGTGATGTTATTG
TATCTTCTAATGAATTAATTAACGAGACAATCGCACAAGAAATCATTGATGCAAAAATTAAAAAAGTTCCTATCCGTAGT
GTTTTGAATTGTAGTTGTGAATACGGTATTTGTGCTAAAGATTATGGTTTTAATTTAGCCACTAATAAACCAGTTGAAGT
CGGTGAAGCCGTTGGAGTTATTGCCGCTCAGTCAATCGGAGAACCAGGAACTCAATTAACTATGAGAACTTTCCATACGG
GTGGTGTTGCCTCAGCATTAGACATTACTCAAGGACTTCCAAGGATTGAAGAATTATTTGAAGCAAGAAAGCCCAAAGGA
AAAGCTTTAATTAGTGAATTTAAAGGAAAAGTTAAAAAAATCAACAAAATCAATTCACCACATCCAGAAATTATTATTAC
TACAACTAACGAAACCGGAGAAAAAGAAAATCTTTATGTTTTAGATCCTAATGTTGACATTTTAGTGAGCAAAAATGATG
ATGTTTATCCAGGACAAAAATTAACTTCAGGATCAATCGATTTAAAAGAACTTTTAAGAGTCGCAGGAACGATTGAAACA
CAAAAATATATTTTAGCAGAAGTGCAAAAAGTTTATCGCGACCAAAACGTTTTTATTAGTGATAAACATATTGAAATCAT
TATTCATCAAATGTTTAAACAAGTTTTTATCATTGATGAAGGTGACACAAAACTTTTACCAGGTACAGAAATTTCTATTA
ATAACTTTAAAAAAGCTAACTTAGAAATGTTAAAAGAAAATAAACGTTTAGCGGTTGGTAGATTAGTTATTTTAGGAATC
ACTCGTGCTTCTTTGAGAAGTGATTCTTTACTTTCTGCTGCATCTTTCCAAGAAACTACAAAAATTTTAATTGATGCTGC
AATCCAAGGGAAATCTGATTATTTATACGGATTAAAAGAAAACGTAATTATCGGCGGTTTAACTCCATCTGGTACAGGCG
TTTTAGAAACTAAAGAATTTGAATATCGTACAAATTCAACTCCTCAAAATGAAAATAAAAATTAA

Upstream 100 bases:

>100_bases
AGCTTTAGGTTTATATGTAGAACTTATTAAAACAGATACTAAGGAAAATGAAGTTAATAAATCTTTAATTGATTACAAAA
AGGAAGGTTATAATTAAAAG

Downstream 100 bases:

>100_bases
ATAAAAATCCAGAAAGGAAATAAAAATATGCCTACAGTCTCTCAATTAATTAAAAAAAGAAGAACTAGCAAAACTACTAA
AACTAAAGCTCCAGCTTTAA

Product: DNA-directed RNA polymerase beta chain

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1354; Mature: 1354

Protein sequence:

>1354_residues
MNDNKLFRSIETLNFSFQTLEKLKLSGINNLEDFNTFSLEELRSLLQETFLEVLPILKQFALPRDLKKLNLNNDIIEKLT
LLGIYDFEQLLKAELPVLTKTFQTDLASWRALNELFELYQHLPPEGLIVSNKKYGSRDYDYFKIRLASPEEIRQWSYGEV
TSYETINYRTYKPEPGGLFCQKIFGPVVDYRCACSKKQISTKSQFCNKCHVEFTETKVRRERMGHIELQAPVVHTWYFNS
SPSRLAVILNIKAKALEEIIYYISYVVIDPGKTDFKEKEIISKSQYSQNLDIFGPNGFVALTGAEAIRKLLENLDLEKTI
KILRKNLSEVSKQKRGALIKRLEIMESLYQSDNNPEWMVMDVIPVLPPGLRPMVPLDGGRFATTEINDLYRRILNRNNRL
KKQMLQKAPSLIIQNEKRMLQEAVDCLFDGDRNVKKNVNNIEKNRPLKSLSEMLRGKQGRFRQNLLGKRVDYSGRSVIIV
GPDLKMHQCGIPREMAIILFKPFILKKLQETKGIDKKNANSIYEKMNEEVWNVLEEVVKEHPVLLNRAPTLHRLGIQAFD
PKLIDGKAIRLHPLVTPAFNADFDGDQMAVYIPLSLEAQAEARLLMLASNNILDPKNGSPVVTPSQDMVLGNYYLTIETK
KDLFAKDLKVSQEDAANHQQKHRNEGAFFADINEVKIAYQSKEIGLHTRIFIKPRSINLSFTEEQKEKYLMTTLGKLIFN
NILPPNFPYINEPTETNLYVKTPDRYFLNPGENPKSFLKKLPLPKPFNKKFLSMIIACFFKQMKITETSKMLDKIKDLGF
KYSTIAGITVSFADINIYSEKDKLLSKVEKRNNQIENWYKQGFLTDAERRRLVINEWKTIRDQIQEGLMKEFPNDNHIFM
MSESGARGSVSNFTQLAGMRGLMNNPKGEIIEVPVKASFREGLKVSEFFISTHGARKGSTDTALKTAESGYLTRRLVDVT
QDVVVIKEDCGSDHSFFVEAMMIDGKEIISLKNRILGRCASRDVLHPKTGDVIVSSNELINETIAQEIIDAKIKKVPIRS
VLNCSCEYGICAKDYGFNLATNKPVEVGEAVGVIAAQSIGEPGTQLTMRTFHTGGVASALDITQGLPRIEELFEARKPKG
KALISEFKGKVKKINKINSPHPEIIITTTNETGEKENLYVLDPNVDILVSKNDDVYPGQKLTSGSIDLKELLRVAGTIET
QKYILAEVQKVYRDQNVFISDKHIEIIIHQMFKQVFIIDEGDTKLLPGTEISINNFKKANLEMLKENKRLAVGRLVILGI
TRASLRSDSLLSAASFQETTKILIDAAIQGKSDYLYGLKENVIIGGLTPSGTGVLETKEFEYRTNSTPQNENKN

Sequences:

>Translated_1354_residues
MNDNKLFRSIETLNFSFQTLEKLKLSGINNLEDFNTFSLEELRSLLQETFLEVLPILKQFALPRDLKKLNLNNDIIEKLT
LLGIYDFEQLLKAELPVLTKTFQTDLASWRALNELFELYQHLPPEGLIVSNKKYGSRDYDYFKIRLASPEEIRQWSYGEV
TSYETINYRTYKPEPGGLFCQKIFGPVVDYRCACSKKQISTKSQFCNKCHVEFTETKVRRERMGHIELQAPVVHTWYFNS
SPSRLAVILNIKAKALEEIIYYISYVVIDPGKTDFKEKEIISKSQYSQNLDIFGPNGFVALTGAEAIRKLLENLDLEKTI
KILRKNLSEVSKQKRGALIKRLEIMESLYQSDNNPEWMVMDVIPVLPPGLRPMVPLDGGRFATTEINDLYRRILNRNNRL
KKQMLQKAPSLIIQNEKRMLQEAVDCLFDGDRNVKKNVNNIEKNRPLKSLSEMLRGKQGRFRQNLLGKRVDYSGRSVIIV
GPDLKMHQCGIPREMAIILFKPFILKKLQETKGIDKKNANSIYEKMNEEVWNVLEEVVKEHPVLLNRAPTLHRLGIQAFD
PKLIDGKAIRLHPLVTPAFNADFDGDQMAVYIPLSLEAQAEARLLMLASNNILDPKNGSPVVTPSQDMVLGNYYLTIETK
KDLFAKDLKVSQEDAANHQQKHRNEGAFFADINEVKIAYQSKEIGLHTRIFIKPRSINLSFTEEQKEKYLMTTLGKLIFN
NILPPNFPYINEPTETNLYVKTPDRYFLNPGENPKSFLKKLPLPKPFNKKFLSMIIACFFKQMKITETSKMLDKIKDLGF
KYSTIAGITVSFADINIYSEKDKLLSKVEKRNNQIENWYKQGFLTDAERRRLVINEWKTIRDQIQEGLMKEFPNDNHIFM
MSESGARGSVSNFTQLAGMRGLMNNPKGEIIEVPVKASFREGLKVSEFFISTHGARKGSTDTALKTAESGYLTRRLVDVT
QDVVVIKEDCGSDHSFFVEAMMIDGKEIISLKNRILGRCASRDVLHPKTGDVIVSSNELINETIAQEIIDAKIKKVPIRS
VLNCSCEYGICAKDYGFNLATNKPVEVGEAVGVIAAQSIGEPGTQLTMRTFHTGGVASALDITQGLPRIEELFEARKPKG
KALISEFKGKVKKINKINSPHPEIIITTTNETGEKENLYVLDPNVDILVSKNDDVYPGQKLTSGSIDLKELLRVAGTIET
QKYILAEVQKVYRDQNVFISDKHIEIIIHQMFKQVFIIDEGDTKLLPGTEISINNFKKANLEMLKENKRLAVGRLVILGI
TRASLRSDSLLSAASFQETTKILIDAAIQGKSDYLYGLKENVIIGGLTPSGTGVLETKEFEYRTNSTPQNENKN
>Mature_1354_residues
MNDNKLFRSIETLNFSFQTLEKLKLSGINNLEDFNTFSLEELRSLLQETFLEVLPILKQFALPRDLKKLNLNNDIIEKLT
LLGIYDFEQLLKAELPVLTKTFQTDLASWRALNELFELYQHLPPEGLIVSNKKYGSRDYDYFKIRLASPEEIRQWSYGEV
TSYETINYRTYKPEPGGLFCQKIFGPVVDYRCACSKKQISTKSQFCNKCHVEFTETKVRRERMGHIELQAPVVHTWYFNS
SPSRLAVILNIKAKALEEIIYYISYVVIDPGKTDFKEKEIISKSQYSQNLDIFGPNGFVALTGAEAIRKLLENLDLEKTI
KILRKNLSEVSKQKRGALIKRLEIMESLYQSDNNPEWMVMDVIPVLPPGLRPMVPLDGGRFATTEINDLYRRILNRNNRL
KKQMLQKAPSLIIQNEKRMLQEAVDCLFDGDRNVKKNVNNIEKNRPLKSLSEMLRGKQGRFRQNLLGKRVDYSGRSVIIV
GPDLKMHQCGIPREMAIILFKPFILKKLQETKGIDKKNANSIYEKMNEEVWNVLEEVVKEHPVLLNRAPTLHRLGIQAFD
PKLIDGKAIRLHPLVTPAFNADFDGDQMAVYIPLSLEAQAEARLLMLASNNILDPKNGSPVVTPSQDMVLGNYYLTIETK
KDLFAKDLKVSQEDAANHQQKHRNEGAFFADINEVKIAYQSKEIGLHTRIFIKPRSINLSFTEEQKEKYLMTTLGKLIFN
NILPPNFPYINEPTETNLYVKTPDRYFLNPGENPKSFLKKLPLPKPFNKKFLSMIIACFFKQMKITETSKMLDKIKDLGF
KYSTIAGITVSFADINIYSEKDKLLSKVEKRNNQIENWYKQGFLTDAERRRLVINEWKTIRDQIQEGLMKEFPNDNHIFM
MSESGARGSVSNFTQLAGMRGLMNNPKGEIIEVPVKASFREGLKVSEFFISTHGARKGSTDTALKTAESGYLTRRLVDVT
QDVVVIKEDCGSDHSFFVEAMMIDGKEIISLKNRILGRCASRDVLHPKTGDVIVSSNELINETIAQEIIDAKIKKVPIRS
VLNCSCEYGICAKDYGFNLATNKPVEVGEAVGVIAAQSIGEPGTQLTMRTFHTGGVASALDITQGLPRIEELFEARKPKG
KALISEFKGKVKKINKINSPHPEIIITTTNETGEKENLYVLDPNVDILVSKNDDVYPGQKLTSGSIDLKELLRVAGTIET
QKYILAEVQKVYRDQNVFISDKHIEIIIHQMFKQVFIIDEGDTKLLPGTEISINNFKKANLEMLKENKRLAVGRLVILGI
TRASLRSDSLLSAASFQETTKILIDAAIQGKSDYLYGLKENVIIGGLTPSGTGVLETKEFEYRTNSTPQNENKN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI39725938, Length=1136, Percent_Identity=25.1760563380282, Blast_Score=217, Evalue=8e-56,
Organism=Homo sapiens, GI4505939, Length=510, Percent_Identity=27.2549019607843, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI103471997, Length=237, Percent_Identity=27.8481012658228, Blast_Score=90, Evalue=1e-17,
Organism=Escherichia coli, GI2367335, Length=981, Percent_Identity=46.8909276248726, Blast_Score=908, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=882, Percent_Identity=24.7165532879819, Blast_Score=195, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71987878, Length=564, Percent_Identity=25.886524822695, Blast_Score=146, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=902, Percent_Identity=24.5011086474501, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320061, Length=537, Percent_Identity=26.4432029795158, Blast_Score=136, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324917, Length=640, Percent_Identity=24.53125, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281360912, Length=1081, Percent_Identity=25.254394079556, Blast_Score=218, Evalue=2e-56,
Organism=Drosophila melanogaster, GI17530899, Length=931, Percent_Identity=24.5972073039742, Blast_Score=191, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17647875, Length=349, Percent_Identity=28.3667621776504, Blast_Score=103, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 153967; Mature: 153967

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNKLFRSIETLNFSFQTLEKLKLSGINNLEDFNTFSLEELRSLLQETFLEVLPILKQF
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALPRDLKKLNLNNDIIEKLTLLGIYDFEQLLKAELPVLTKTFQTDLASWRALNELFELYQ
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HLPPEGLIVSNKKYGSRDYDYFKIRLASPEEIRQWSYGEVTSYETINYRTYKPEPGGLFC
HCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCEEEEEEEEECCCCCCHHH
QKIFGPVVDYRCACSKKQISTKSQFCNKCHVEFTETKVRRERMGHIELQAPVVHTWYFNS
HHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCEEEEEEECC
SPSRLAVILNIKAKALEEIIYYISYVVIDPGKTDFKEKEIISKSQYSQNLDIFGPNGFVA
CCCEEEEEEECHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCEEE
LTGAEAIRKLLENLDLEKTIKILRKNLSEVSKQKRGALIKRLEIMESLYQSDNNPEWMVM
EECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DVIPVLPPGLRPMVPLDGGRFATTEINDLYRRILNRNNRLKKQMLQKAPSLIIQNEKRML
EEHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCHHEEHHHHHHH
QEAVDCLFDGDRNVKKNVNNIEKNRPLKSLSEMLRGKQGRFRQNLLGKRVDYSGRSVIIV
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEE
GPDLKMHQCGIPREMAIILFKPFILKKLQETKGIDKKNANSIYEKMNEEVWNVLEEVVKE
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFDPKLIDGKAIRLHPLVTPAFNADFDGDQMAVYIPLSLEAQA
CCEEECCCCCHHHCCCHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEECCCC
EARLLMLASNNILDPKNGSPVVTPSQDMVLGNYYLTIETKKDLFAKDLKVSQEDAANHQQ
CEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEEEEECCHHHHHHHCCCCHHHHHHHHH
KHRNEGAFFADINEVKIAYQSKEIGLHTRIFIKPRSINLSFTEEQKEKYLMTTLGKLIFN
HHCCCCCEEEECCCEEEEEECCCCCCEEEEEEEECEEEEEECHHHHHHHHHHHHHHHHHH
NILPPNFPYINEPTETNLYVKTPDRYFLNPGENPKSFLKKLPLPKPFNKKFLSMIIACFF
HCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
KQMKITETSKMLDKIKDLGFKYSTIAGITVSFADINIYSEKDKLLSKVEKRNNQIENWYK
HHHHHHHHHHHHHHHHHCCCCEEEEECEEEEEEEEEEECHHHHHHHHHHHHCHHHHHHHH
QGFLTDAERRRLVINEWKTIRDQIQEGLMKEFPNDNHIFMMSESGARGSVSNFTQLAGMR
HCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
GLMNNPKGEIIEVPVKASFREGLKVSEFFISTHGARKGSTDTALKTAESGYLTRRLVDVT
HHCCCCCCCEEEECCCHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHH
QDVVVIKEDCGSDHSFFVEAMMIDGKEIISLKNRILGRCASRDVLHPKTGDVIVSSNELI
HCEEEEECCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHH
NETIAQEIIDAKIKKVPIRSVLNCSCEYGICAKDYGFNLATNKPVEVGEAVGVIAAQSIG
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPGTQLTMRTFHTGGVASALDITQGLPRIEELFEARKPKGKALISEFKGKVKKINKINSP
CCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
HPEIIITTTNETGEKENLYVLDPNVDILVSKNDDVYPGQKLTSGSIDLKELLRVAGTIET
CCCEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCHHH
QKYILAEVQKVYRDQNVFISDKHIEIIIHQMFKQVFIIDEGDTKLLPGTEISINNFKKAN
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHEEEEECCCCEECCCCEEECCCCCHHH
LEMLKENKRLAVGRLVILGITRASLRSDSLLSAASFQETTKILIDAAIQGKSDYLYGLKE
HHHHHCCCCEEEEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NVIIGGLTPSGTGVLETKEFEYRTNSTPQNENKN
CEEEECCCCCCCCEEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNDNKLFRSIETLNFSFQTLEKLKLSGINNLEDFNTFSLEELRSLLQETFLEVLPILKQF
CCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALPRDLKKLNLNNDIIEKLTLLGIYDFEQLLKAELPVLTKTFQTDLASWRALNELFELYQ
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HLPPEGLIVSNKKYGSRDYDYFKIRLASPEEIRQWSYGEVTSYETINYRTYKPEPGGLFC
HCCCCCEEEECCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCEEEEEEEEECCCCCCHHH
QKIFGPVVDYRCACSKKQISTKSQFCNKCHVEFTETKVRRERMGHIELQAPVVHTWYFNS
HHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCEEEEEEECC
SPSRLAVILNIKAKALEEIIYYISYVVIDPGKTDFKEKEIISKSQYSQNLDIFGPNGFVA
CCCEEEEEEECHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCCEEE
LTGAEAIRKLLENLDLEKTIKILRKNLSEVSKQKRGALIKRLEIMESLYQSDNNPEWMVM
EECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DVIPVLPPGLRPMVPLDGGRFATTEINDLYRRILNRNNRLKKQMLQKAPSLIIQNEKRML
EEHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCHHEEHHHHHHH
QEAVDCLFDGDRNVKKNVNNIEKNRPLKSLSEMLRGKQGRFRQNLLGKRVDYSGRSVIIV
HHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEE
GPDLKMHQCGIPREMAIILFKPFILKKLQETKGIDKKNANSIYEKMNEEVWNVLEEVVKE
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFDPKLIDGKAIRLHPLVTPAFNADFDGDQMAVYIPLSLEAQA
CCEEECCCCCHHHCCCHHCCCEEECCCEEEEEEEECCCCCCCCCCCCEEEEEEEEECCCC
EARLLMLASNNILDPKNGSPVVTPSQDMVLGNYYLTIETKKDLFAKDLKVSQEDAANHQQ
CEEEEEEECCCCCCCCCCCEEECCCCCEEEEEEEEEEECCHHHHHHHCCCCHHHHHHHHH
KHRNEGAFFADINEVKIAYQSKEIGLHTRIFIKPRSINLSFTEEQKEKYLMTTLGKLIFN
HHCCCCCEEEECCCEEEEEECCCCCCEEEEEEEECEEEEEECHHHHHHHHHHHHHHHHHH
NILPPNFPYINEPTETNLYVKTPDRYFLNPGENPKSFLKKLPLPKPFNKKFLSMIIACFF
HCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
KQMKITETSKMLDKIKDLGFKYSTIAGITVSFADINIYSEKDKLLSKVEKRNNQIENWYK
HHHHHHHHHHHHHHHHHCCCCEEEEECEEEEEEEEEEECHHHHHHHHHHHHCHHHHHHHH
QGFLTDAERRRLVINEWKTIRDQIQEGLMKEFPNDNHIFMMSESGARGSVSNFTQLAGMR
HCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
GLMNNPKGEIIEVPVKASFREGLKVSEFFISTHGARKGSTDTALKTAESGYLTRRLVDVT
HHCCCCCCCEEEECCCHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHH
QDVVVIKEDCGSDHSFFVEAMMIDGKEIISLKNRILGRCASRDVLHPKTGDVIVSSNELI
HCEEEEECCCCCCHHEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHH
NETIAQEIIDAKIKKVPIRSVLNCSCEYGICAKDYGFNLATNKPVEVGEAVGVIAAQSIG
HHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPGTQLTMRTFHTGGVASALDITQGLPRIEELFEARKPKGKALISEFKGKVKKINKINSP
CCCCEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
HPEIIITTTNETGEKENLYVLDPNVDILVSKNDDVYPGQKLTSGSIDLKELLRVAGTIET
CCCEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCHHH
QKYILAEVQKVYRDQNVFISDKHIEIIIHQMFKQVFIIDEGDTKLLPGTEISINNFKKAN
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHEEEEECCCCEECCCCEEECCCCCHHH
LEMLKENKRLAVGRLVILGITRASLRSDSLLSAASFQETTKILIDAAIQGKSDYLYGLKE
HHHHHCCCCEEEEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
NVIIGGLTPSGTGVLETKEFEYRTNSTPQNENKN
CEEEECCCCCCCCEEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA