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The map label for this gene is znuA [H]

Identifier: 197294526

GI number: 197294526

Start: 476283

End: 477404

Strand: Direct

Name: znuA [H]

Synonym: PAa_0481

Alternate gene names: 197294526

Gene position: 476283-477404 (Clockwise)

Preceding gene: 197294525

Following gene: 197294527

Centisome position: 54.13

GC content: 27.72

Gene sequence:

>1122_bases
ATGATTCCTGAAAAAGAAAAAAAACAAAAATTCATTGTTATTTTTTTAATTTTGATAATAACTTTTTTTATTTTGGTGAT
TCCTGTTAGTGCTTTTTATTCAAAACCAACAAAACAAGATGAAAACACAAAAAAGATAGTAGTAACAACAACTATGTTAC
AAGATTTAGTTAAGCATTTAATCGGTGATGTTGATAAAGAGGAAACTCAAAAATCAGAAACTTATCAAAAAATCGAAGGA
ATTACTTGTGAAACTTTAATGGGAGTAGGAATTGATCCTCATAATTATAAAATTAAATTATCAGATCGTTTAAAACTTAA
AAATGCTGATTTAGTAGTTGTTAGTGGCCTCCATTTAGAAGCCAAAATGCCTGAAGCTTTTCAACGTTTTACCAAACAGG
ATCGCTTTTGGGATGCAGGAAATGCCTTAATTAAAGACTCTGAACTGAAAAATTTATTAAAACAAACAGATTCTTATGAA
TACGACCCTCATATTTGGTTTGAAATTGATTTATGGATCGAAACTTTCAAAAACTTAAAACAAACTCTTTTAGACAAAAA
AATTGTGAAAGAAAAAGATAAAAAGAAATTAGAGGCTAATTTTGGTATTTACAATAAGGCTTTGGAGCAATTAAAAGAGA
AAATAATTAATGAAATGATTGAATTAAAAATAAACCTAAACAACAAACTAATTATAGTTACTGCTCACGATGCTTTTGCT
TATTGGGAATCTTTTTGTCAAAAACAAAAAAAAAATTGTGATTTTGATTTAGAATCAATTCAAGGAATTTCTACTCAAAC
CGAAGCTAGTAATAATAAAATTGTCGCTTTAGCTGAAAAATTAGTCAAAAACGATGTAAAAGCCATTTTTACTGAATCTT
CGATGCCTAAAAATTCTTTACAAAGTTTAAAAGAACAGGTAGATAGCGAAAGAAGACGCAAAGGCCTTCAAGGTGAGATT
CAAATTCCTGAAAACATGGAATTATATTCCGATTCCTTAGGAACAGATAAACAACAAGAAGAATTAGAAAATAACAAATA
TAAACATTCCACCTATATTGGTGCTTTTTTAAACAATATTAAAGTCATCAAAACCTATTTATCGCCAAAAACCATAACAT
AA

Upstream 100 bases:

>100_bases
AAGTGATTTTTAAAGAATAAAGATTATTTAATGATTAATTTTTTCCAAAAAAATAATAATAAAAATTTTTAAGAAAGCTC
ATCCTTAGAAAGAGTTCAAA

Downstream 100 bases:

>100_bases
TAAAAAGACAAAAAATCAATAAAATATAAATATACTTTTTTTACCGTTTGCATTTAACAATTAGAAGTTATTAAAAAATA
TCATAACATAATAAAAAGAA

Product: ABC-type Zn/Mn transport system periplasmic component/surface adhesion

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Tromp-1 [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MIPEKEKKQKFIVIFLILIITFFILVIPVSAFYSKPTKQDENTKKIVVTTTMLQDLVKHLIGDVDKEETQKSETYQKIEG
ITCETLMGVGIDPHNYKIKLSDRLKLKNADLVVVSGLHLEAKMPEAFQRFTKQDRFWDAGNALIKDSELKNLLKQTDSYE
YDPHIWFEIDLWIETFKNLKQTLLDKKIVKEKDKKKLEANFGIYNKALEQLKEKIINEMIELKINLNNKLIIVTAHDAFA
YWESFCQKQKKNCDFDLESIQGISTQTEASNNKIVALAEKLVKNDVKAIFTESSMPKNSLQSLKEQVDSERRRKGLQGEI
QIPENMELYSDSLGTDKQQEELENNKYKHSTYIGAFLNNIKVIKTYLSPKTIT

Sequences:

>Translated_373_residues
MIPEKEKKQKFIVIFLILIITFFILVIPVSAFYSKPTKQDENTKKIVVTTTMLQDLVKHLIGDVDKEETQKSETYQKIEG
ITCETLMGVGIDPHNYKIKLSDRLKLKNADLVVVSGLHLEAKMPEAFQRFTKQDRFWDAGNALIKDSELKNLLKQTDSYE
YDPHIWFEIDLWIETFKNLKQTLLDKKIVKEKDKKKLEANFGIYNKALEQLKEKIINEMIELKINLNNKLIIVTAHDAFA
YWESFCQKQKKNCDFDLESIQGISTQTEASNNKIVALAEKLVKNDVKAIFTESSMPKNSLQSLKEQVDSERRRKGLQGEI
QIPENMELYSDSLGTDKQQEELENNKYKHSTYIGAFLNNIKVIKTYLSPKTIT
>Mature_373_residues
MIPEKEKKQKFIVIFLILIITFFILVIPVSAFYSKPTKQDENTKKIVVTTTMLQDLVKHLIGDVDKEETQKSETYQKIEG
ITCETLMGVGIDPHNYKIKLSDRLKLKNADLVVVSGLHLEAKMPEAFQRFTKQDRFWDAGNALIKDSELKNLLKQTDSYE
YDPHIWFEIDLWIETFKNLKQTLLDKKIVKEKDKKKLEANFGIYNKALEQLKEKIINEMIELKINLNNKLIIVTAHDAFA
YWESFCQKQKKNCDFDLESIQGISTQTEASNNKIVALAEKLVKNDVKAIFTESSMPKNSLQSLKEQVDSERRRKGLQGEI
QIPENMELYSDSLGTDKQQEELENNKYKHSTYIGAFLNNIKVIKTYLSPKTIT

Specific function: Part of an ATP-driven transport system troABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 43224; Mature: 43224

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPEKEKKQKFIVIFLILIITFFILVIPVSAFYSKPTKQDENTKKIVVTTTMLQDLVKHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHH
IGDVDKEETQKSETYQKIEGITCETLMGVGIDPHNYKIKLSDRLKLKNADLVVVSGLHLE
HCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEECCCCC
AKMPEAFQRFTKQDRFWDAGNALIKDSELKNLLKQTDSYEYDPHIWFEIDLWIETFKNLK
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHH
QTLLDKKIVKEKDKKKLEANFGIYNKALEQLKEKIINEMIELKINLNNKLIIVTAHDAFA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHH
YWESFCQKQKKNCDFDLESIQGISTQTEASNNKIVALAEKLVKNDVKAIFTESSMPKNSL
HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
QSLKEQVDSERRRKGLQGEIQIPENMELYSDSLGTDKQQEELENNKYKHSTYIGAFLNNI
HHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
KVIKTYLSPKTIT
HHHHHHCCCCCCC
>Mature Secondary Structure
MIPEKEKKQKFIVIFLILIITFFILVIPVSAFYSKPTKQDENTKKIVVTTTMLQDLVKHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHH
IGDVDKEETQKSETYQKIEGITCETLMGVGIDPHNYKIKLSDRLKLKNADLVVVSGLHLE
HCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCEEECCCCEEEEECCCCC
AKMPEAFQRFTKQDRFWDAGNALIKDSELKNLLKQTDSYEYDPHIWFEIDLWIETFKNLK
CCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHH
QTLLDKKIVKEKDKKKLEANFGIYNKALEQLKEKIINEMIELKINLNNKLIIVTAHDAFA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHH
YWESFCQKQKKNCDFDLESIQGISTQTEASNNKIVALAEKLVKNDVKAIFTESSMPKNSL
HHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
QSLKEQVDSERRRKGLQGEIQIPENMELYSDSLGTDKQQEELENNKYKHSTYIGAFLNNI
HHHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
KVIKTYLSPKTIT
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7768866; 9332349; 9665876; 10400603; 10404217 [H]