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The map label for this gene is holA [H]

Identifier: 197294282

GI number: 197294282

Start: 174078

End: 175040

Strand: Direct

Name: holA [H]

Synonym: PAa_0145

Alternate gene names: 197294282

Gene position: 174078-175040 (Clockwise)

Preceding gene: 197294275

Following gene: 197294290

Centisome position: 19.78

GC content: 23.68

Gene sequence:

>963_bases
ATGTCAAAAAATAACATATATTTAATTTCAGGAAAACAAAGGTTTTTTCTTGAACAAAAAATTAAAAAACTAATCATCAC
TTTTCAAAATCAATCTTTGGATGTCGTTCATTATCGAATGCAAAAAGATGCTGATAGTGATTTAGAAAAAGAACTAAAAG
TTATTCCACTTTTGCATAAAGTAATTATTGTTGATCAAAGCGAAATTTTGTTACAAAAGAAAAAAAAAGAATTAACTTTT
TTAAATTCTTACTTTCAAAACCCATCTCCCAAGATTTCTTTATATTTTTTTGTAGAAAACGGACTTGAAAATAACGAAAA
TTTTCAATTGTTTCAAAAATATTGTTCTTGTGAAACAATTGTGTCTTTGGAAAAAAACGATTTTTTTACTTATGTTGCAG
AATCATTTGAAAAAGAAGGTTTTCAAATAGAAAAAAAAGCTATTTATCATTTATTAAAAGAAACAAATTATAATCTTTTT
TTTCTTCACCAAGAAATCAAAAAATTAAAATTATGTCAACTGGAAGAAAAAACAATCACTTATCCATTAGTTGAAAAATT
AAATTTTTTTCAAACAGAAGACAACCTTTTTCATTTAATTAACCTTTTTTTAAATAATAATCGAATTGGGGCTTATGAAT
TGTATCAAAAATTCAAAAAGCACAAAAACAACGCTTTCCAAATATTATATCAATTAACTAACAAAATTAAAGCTTTATTA
TTAGTAAAAAATATGGTTAAACAAAATTATAATCAAGAAAAAATCTCCCAAATTCTTAAATGTTCTCCTGCAAAAGCGTT
CCTTTTAACTAAGGAAGCCCAAGTTTTTAAAAACACTCAATTTTTACAAGCTTCTTTTTTGACTTTAATAGAATTAGAAT
ATCAATCCAAAATAGGTTCTATCAATCTAGATACCGGTTTGGAATTCTTTTTCTTAGGTAAAAATATTTTGCCATTATCA
TAA

Upstream 100 bases:

>100_bases
AGTAAATTAAATAATTGCATTCGTTGACTCTCTTATTTGATAAAATAATTAATAGTAATAGATTAATGTTTCAAAAAACT
AGAAAAATGAGTTTGAGTAA

Downstream 100 bases:

>100_bases
TTTTGCAATTTTTTTAATTTCTGCTTCACTAATGCTTCCTTGTCTTAAAACAATCAATTTATTAGTGGTTGCATCAACAA
TAGTAGAAGCCACTTTCAAA

Product: DNA polymerase III, delta subunit

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSKNNIYLISGKQRFFLEQKIKKLIITFQNQSLDVVHYRMQKDADSDLEKELKVIPLLHKVIIVDQSEILLQKKKKELTF
LNSYFQNPSPKISLYFFVENGLENNENFQLFQKYCSCETIVSLEKNDFFTYVAESFEKEGFQIEKKAIYHLLKETNYNLF
FLHQEIKKLKLCQLEEKTITYPLVEKLNFFQTEDNLFHLINLFLNNNRIGAYELYQKFKKHKNNAFQILYQLTNKIKALL
LVKNMVKQNYNQEKISQILKCSPAKAFLLTKEAQVFKNTQFLQASFLTLIELEYQSKIGSINLDTGLEFFFLGKNILPLS

Sequences:

>Translated_320_residues
MSKNNIYLISGKQRFFLEQKIKKLIITFQNQSLDVVHYRMQKDADSDLEKELKVIPLLHKVIIVDQSEILLQKKKKELTF
LNSYFQNPSPKISLYFFVENGLENNENFQLFQKYCSCETIVSLEKNDFFTYVAESFEKEGFQIEKKAIYHLLKETNYNLF
FLHQEIKKLKLCQLEEKTITYPLVEKLNFFQTEDNLFHLINLFLNNNRIGAYELYQKFKKHKNNAFQILYQLTNKIKALL
LVKNMVKQNYNQEKISQILKCSPAKAFLLTKEAQVFKNTQFLQASFLTLIELEYQSKIGSINLDTGLEFFFLGKNILPLS
>Mature_319_residues
SKNNIYLISGKQRFFLEQKIKKLIITFQNQSLDVVHYRMQKDADSDLEKELKVIPLLHKVIIVDQSEILLQKKKKELTFL
NSYFQNPSPKISLYFFVENGLENNENFQLFQKYCSCETIVSLEKNDFFTYVAESFEKEGFQIEKKAIYHLLKETNYNLFF
LHQEIKKLKLCQLEEKTITYPLVEKLNFFQTEDNLFHLINLFLNNNRIGAYELYQKFKKHKNNAFQILYQLTNKIKALLL
VKNMVKQNYNQEKISQILKCSPAKAFLLTKEAQVFKNTQFLQASFLTLIELEYQSKIGSINLDTGLEFFFLGKNILPLS

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 37907; Mature: 37775

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNNIYLISGKQRFFLEQKIKKLIITFQNQSLDVVHYRMQKDADSDLEKELKVIPLLHK
CCCCCEEEEECCHHHHHHHHHHHHEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHH
VIIVDQSEILLQKKKKELTFLNSYFQNPSPKISLYFFVENGLENNENFQLFQKYCSCETI
HHEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCHHHE
VSLEKNDFFTYVAESFEKEGFQIEKKAIYHLLKETNYNLFFLHQEIKKLKLCQLEEKTIT
EEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCH
YPLVEKLNFFQTEDNLFHLINLFLNNNRIGAYELYQKFKKHKNNAFQILYQLTNKIKALL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LVKNMVKQNYNQEKISQILKCSPAKAFLLTKEAQVFKNTQFLQASFLTLIELEYQSKIGS
HHHHHHHCCCCHHHHHHHHHCCCCHHEEEEHHHHHHHCHHHHHHHHHHHHEEEHHHCCCC
INLDTGLEFFFLGKNILPLS
EECCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SKNNIYLISGKQRFFLEQKIKKLIITFQNQSLDVVHYRMQKDADSDLEKELKVIPLLHK
CCCCEEEEECCHHHHHHHHHHHHEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHH
VIIVDQSEILLQKKKKELTFLNSYFQNPSPKISLYFFVENGLENNENFQLFQKYCSCETI
HHEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCHHHE
VSLEKNDFFTYVAESFEKEGFQIEKKAIYHLLKETNYNLFFLHQEIKKLKLCQLEEKTIT
EEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCH
YPLVEKLNFFQTEDNLFHLINLFLNNNRIGAYELYQKFKKHKNNAFQILYQLTNKIKALL
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LVKNMVKQNYNQEKISQILKCSPAKAFLLTKEAQVFKNTQFLQASFLTLIELEYQSKIGS
HHHHHHHCCCCHHHHHHHHHCCCCHHEEEEHHHHHHHCHHHHHHHHHHHHEEEHHHCCCC
INLDTGLEFFFLGKNILPLS
EECCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]