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The map label for this gene is gcp

Identifier: 197294235

GI number: 197294235

Start: 101900

End: 102886

Strand: Direct

Name: gcp

Synonym: PAa_0093

Alternate gene names: 197294235

Gene position: 101900-102886 (Clockwise)

Preceding gene: 197294234

Following gene: 197294236

Centisome position: 11.58

GC content: 31.41

Gene sequence:

>987_bases
ATGAATATTTTATCCATCGAAACAAGTTGCGATGAAACAAGTGTTGCCATTACTCAAGACGGTAAAAAAGTTTTATCTAA
TATAGTTTTTTCTCAAATCAAAGACCACCAAATGTTTGGTGGTGTAGTTCCTGAAATAGCTTCTAGAAAACATGTTGAAT
TAATTACTTTAATTTTAGAAAAAGCTTTCCAAAAAGCTTGTCTTACACCCCAAGAAATTGATTTAGTAGCGGTTACTCAA
GGACCTGGTTTAGTGGGATCTTTGTTAGTGGGCATCAATGCAGCTAATGTTTTTGCCTACACTTATCAAAAACCTCTTTT
AGGAATCAACCATCTTTTAGGACATCTTTATGCCGCTCAAATTGAACATCAAATTAAACCAAATGCGTTAATTCTTTTAG
TTTCAGGAGGACATACAGAACTTCTTCATTTTAAAAATCATGATCAAATAGAAGTTTTGGGAACAACTCTAGATGATGCT
TTAGGAGAAGTTTACGATAAAATAGCCAAAGCCCTTCATTTAGGATATCCAGGAGGCCCTTTAATTGATCAATTAGCCCA
AACAGGCAAAGATACTTATCATTTAGTGAGACCTTATTTAAAAAATAATAATTTCAATTTTAGTTTTTCAGGCCTTAAAA
GCCATTTAGTTAATTTATTATTGAAACAAAACATTCAAGATTTAAATATCCCAAACATATGTGCTTCTTTTCAAGCAAGT
GTTATTGATGTTTTATTAACCAAAACTAAAAGAGTTTTAAAAAAATTACCTATTCAACAATTGATTGTAACAGGAGGGGT
TGCCTCTAATTCTGCTTTAAGAAAAAAAATGAAAGAAACTTTCCTTGATTTAGAAGTAATTTTTCCAAGCGTTCAATATT
GCACCGATCAAGCGGCCATGATAGGAATTGCTGCTTTTTATCAAAAAAATATCACCCCCCCTTCATATAAATATGATTTA
ACTGCTTTGCCAAATTTAACTTTTTAA

Upstream 100 bases:

>100_bases
TTATCTTAAAATTTCGCTTTTATTACTTCATCAAATTTTTTTAATCTTTTCAAAAATATAAAATCATTTTTTTACAAATT
AAATTAAAAAGGAAGAGATT

Downstream 100 bases:

>100_bases
AAAAAATGTTTTTTTAATTTTTTTTGCGATAACTTTTTTTTAATCTTAAAAAGATTGCGATAATTACAATTTCTTCGGAT
TCAAAAAATCTTTACTTGAA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNILSIETSCDETSVAITQDGKKVLSNIVFSQIKDHQMFGGVVPEIASRKHVELITLILEKAFQKACLTPQEIDLVAVTQ
GPGLVGSLLVGINAANVFAYTYQKPLLGINHLLGHLYAAQIEHQIKPNALILLVSGGHTELLHFKNHDQIEVLGTTLDDA
LGEVYDKIAKALHLGYPGGPLIDQLAQTGKDTYHLVRPYLKNNNFNFSFSGLKSHLVNLLLKQNIQDLNIPNICASFQAS
VIDVLLTKTKRVLKKLPIQQLIVTGGVASNSALRKKMKETFLDLEVIFPSVQYCTDQAAMIGIAAFYQKNITPPSYKYDL
TALPNLTF

Sequences:

>Translated_328_residues
MNILSIETSCDETSVAITQDGKKVLSNIVFSQIKDHQMFGGVVPEIASRKHVELITLILEKAFQKACLTPQEIDLVAVTQ
GPGLVGSLLVGINAANVFAYTYQKPLLGINHLLGHLYAAQIEHQIKPNALILLVSGGHTELLHFKNHDQIEVLGTTLDDA
LGEVYDKIAKALHLGYPGGPLIDQLAQTGKDTYHLVRPYLKNNNFNFSFSGLKSHLVNLLLKQNIQDLNIPNICASFQAS
VIDVLLTKTKRVLKKLPIQQLIVTGGVASNSALRKKMKETFLDLEVIFPSVQYCTDQAAMIGIAAFYQKNITPPSYKYDL
TALPNLTF
>Mature_328_residues
MNILSIETSCDETSVAITQDGKKVLSNIVFSQIKDHQMFGGVVPEIASRKHVELITLILEKAFQKACLTPQEIDLVAVTQ
GPGLVGSLLVGINAANVFAYTYQKPLLGINHLLGHLYAAQIEHQIKPNALILLVSGGHTELLHFKNHDQIEVLGTTLDDA
LGEVYDKIAKALHLGYPGGPLIDQLAQTGKDTYHLVRPYLKNNNFNFSFSGLKSHLVNLLLKQNIQDLNIPNICASFQAS
VIDVLLTKTKRVLKKLPIQQLIVTGGVASNSALRKKMKETFLDLEVIFPSVQYCTDQAAMIGIAAFYQKNITPPSYKYDL
TALPNLTF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=327, Percent_Identity=29.3577981651376, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI8923380, Length=310, Percent_Identity=29.0322580645161, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1789445, Length=312, Percent_Identity=40.7051282051282, Blast_Score=248, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=29.8461538461538, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71995670, Length=314, Percent_Identity=29.2993630573248, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=339, Percent_Identity=33.6283185840708, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322891, Length=290, Percent_Identity=25.8620689655172, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI20129063, Length=351, Percent_Identity=33.048433048433, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357207, Length=318, Percent_Identity=27.6729559748428, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PHYAS (B1V8Z6)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001798776.1
- ProteinModelPortal:   B1V8Z6
- SMR:   B1V8Z6
- MEROPS:   M22.001
- GeneID:   6799210
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36072; Mature: 36072

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILSIETSCDETSVAITQDGKKVLSNIVFSQIKDHQMFGGVVPEIASRKHVELITLILE
CCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
KAFQKACLTPQEIDLVAVTQGPGLVGSLLVGINAANVFAYTYQKPLLGINHLLGHLYAAQ
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHHH
IEHQIKPNALILLVSGGHTELLHFKNHDQIEVLGTTLDDALGEVYDKIAKALHLGYPGGP
HHHCCCCCEEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCH
LIDQLAQTGKDTYHLVRPYLKNNNFNFSFSGLKSHLVNLLLKQNIQDLNIPNICASFQAS
HHHHHHHCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VIDVLLTKTKRVLKKLPIQQLIVTGGVASNSALRKKMKETFLDLEVIFPSVQYCTDQAAM
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHH
IGIAAFYQKNITPPSYKYDLTALPNLTF
HHHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MNILSIETSCDETSVAITQDGKKVLSNIVFSQIKDHQMFGGVVPEIASRKHVELITLILE
CCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHH
KAFQKACLTPQEIDLVAVTQGPGLVGSLLVGINAANVFAYTYQKPLLGINHLLGHLYAAQ
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHHH
IEHQIKPNALILLVSGGHTELLHFKNHDQIEVLGTTLDDALGEVYDKIAKALHLGYPGGP
HHHCCCCCEEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCH
LIDQLAQTGKDTYHLVRPYLKNNNFNFSFSGLKSHLVNLLLKQNIQDLNIPNICASFQAS
HHHHHHHCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VIDVLLTKTKRVLKKLPIQQLIVTGGVASNSALRKKMKETFLDLEVIFPSVQYCTDQAAM
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHH
IGIAAFYQKNITPPSYKYDLTALPNLTF
HHHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA